adheal plus tablet - Trypsin (48mg) + Bromelain (90mg) medicine

adheal plus tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Indian Drugs & Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is adheal plus tablet used for?

Actiheal-D Tablet (Trypsin + Bromelain) is used to treat PAIN ANALGESICS. It contains Trypsin (48mg) + Bromelain (90mg), which Trypsin and bromelain are proteolytic enzymes that break down proteins involved . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Trypsin + Bromelain
  • Manufacturer: Indian Drugs & Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š adheal plus tablet Uses & Benefits

Reduction of inflammation and edema in conditions like trauma, surgery, sinusitis, and thrombophlebitis.

Off-label uses: Chronic inflammation, Fibrocystic breast disease

๐Ÿ“‹ Drug Information

Generic Name(s)Trypsin + Bromelain
Brand NameActiheal-D Tablet
ManufacturerIndian Drugs & Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassProteolytic Enzymes
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed from gastrointestinal tract after oral administration.
DistributionDistributed throughout the body, with higher concentrations at sites of inflammation.
Protein BindingNot well characterized; likely low.
MetabolismMetabolized by proteolysis.
Half-LifeTrypsin: ~2-3 hours; Bromelain: ~6-9 hours.
ExcretionExcreted primarily in urine as metabolites.
BioavailabilityLow due to first-pass metabolism; enhanced by enteric coating.
Onset of ActionWithin 1-2 hours.
Peak Plasma TimeTrypsin: 2-3 hours; Bromelain: 1-2 hours.
Duration of Action4-6 hours.

How It Works

Trypsin and bromelain are proteolytic enzymes that break down proteins involved in inflammation and edema, reducing swelling and pain.

Mechanism Steps

1Trypsin and bromelain hydrolyze peptide bonds in proteins.
2Degrade pro-inflammatory mediators like bradykinin and fibrin.
3Reduce capillary permeability and edema.

๐Ÿ’ก How to Take adheal plus tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of adheal plus tablet

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Abdominal discomfort

๐Ÿšจ Serious Side Effects

  • Allergic reactions
  • Bleeding

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Major Increased bleeding risk
Clopidogrel Major Increased bleeding risk
Heparin Major Increased bleeding risk

๐Ÿšจ Major Interactions

  • Anticoagulants
  • Antiplatelet agents

โšก Moderate Interactions

  • Antibiotics
  • NSAIDs

โ„น๏ธ Minor Interactions

  • Herbal supplements with anticoagulant properties

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to trypsin or bromelain, severe liver or kidney impairment, bleeding disorders.

๐Ÿ“Š Monitoring Parameters

Monitor for signs of bleeding, allergic reactions.

๐Ÿคฑ Lactation Safety

Excretion in milk unknown; caution advised.

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; no specific antidote.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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