acybronk tablet - Acetylcysteine (200mg) + Ambroxol (30mg) medicine

Acybronk Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 Cascade India Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for mucolytic use in respiratory conditions with thick secretions.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Severe allergic rash or blistering

If experiencing severe symptoms, call emergency services immediately.

What is acybronk tablet used for?

This medicine is a combination of acetylcysteine and ambroxol, used to treat respiratory conditions with thick mucus. It works by thinning mucus and helping you cough it out more easily. It is taken orally, usually twice daily with food. Do not use it for more than 7 days without consulting a doctor.

  • Generic Name: Acetylcysteine (200mg) + Ambroxol (30mg)
  • Manufacturer: Cascade India Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 acybronk tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एसिटाइलसिस्टीन और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग श्वसन संबंधी समस्याओं में गाढ़े बलगम को पतला करने और उसे आसानी से बाहर निकालने के लिए किया जाता है। यह ब्रोंकाइटिस, सीओपीडी और अन्य स्थितियों में लाभकारी है जहां बलगम गाढ़ा और चिपचिपा हो जाता है। यह दवा मुंह से ली जाती है और आमतौर पर भोजन के साथ दिन में दो बार लेने की सलाह दी जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट में असहजता, और जलन शामिल हैं। कुछ लोगों को मुंह सूखना, स्वाद में बदलाव, या नाक बहना भी हो सकता है। दुर्लभ मामलों में एलर्जी प्रतिक्रिया जैसे त्वचा पर चकत्ते, खुजली, या चेहरे, होंठ, या गले में सूजन हो सकती है, जिसके लिए तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। गोली को पानी के साथ पूरा निगलें, चबाएं नहीं। इसे भोजन के साथ लेने से पेट की परेशानी कम होती है। यदि आपको पेप्टिक अल्सर, अस्थमा, या गुर्दे या यकृत की समस्या है, तो डॉक्टर को बताएं। इस दवा के साथ शराब न लें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 acybronk tablet Uses & Benefits

[{"condition":"Acute bronchitis","description":"Helps thin and clear thick mucus, making cough more productive and relieving chest congestion.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Reduces mucus viscosity and improves clearance of secretions in chronic bronchitis.","evidence":"Well-established"},{"condition":"COPD (Chronic Obstructive Pulmonary Disease)","description":"Used as a mucolytic to ease expectoration and improve symptoms in COPD patients with thick secretions.","evidence":"Moderate"},{"condition":"Bronchiectasis","description":"May help in clearing excessive mucus in bronchiectasis, but evidence is limited.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of contrast-induced nephropathy","description":"Acetylcysteine has been studied for preventing kidney damage from contrast dyes, but evidence is conflicting and it is not a standard use for this combination.","evidence":"Limited"},{"condition":"Infertility (cervical mucus thickening)","description":"Acetylcysteine has been used off-label to thin cervical mucus in fertility treatment, but this is not a standard use for this combination product.","evidence":"Limited"}]

Primary treatment for: Respiratory conditions with thick mucus (e.g., bronchitis, COPD)

Also treats: Chronic bronchitis, COPD, Bronchiectasis, Acute bronchitis

📋 Drug Information

Generic Name(s)Acetylcysteine (200mg) + Ambroxol (30mg)
Brand Nameacybronk tablet
ManufacturerCascade India Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep the tablets in their original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day to help thin mucus.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
If you have asthma, use with caution and inform your doctor.
8
Do not combine with cough suppressants unless advised.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not effective for dry cough.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBoth acetylcysteine and ambroxol are rapidly absorbed from the gastrointestinal tract after oral administration. Acetylcysteine undergoes first-pass metabolism, resulting in low oral bioavailability. Ambroxol is well absorbed and undergoes some first-pass metabolism.
DistributionAcetylcysteine is distributed widely in body fluids and tissues. Ambroxol is distributed extensively into tissues, including lung tissue, where it reaches higher concentrations than in plasma.
Protein BindingAcetylcysteine is approximately 50% bound to plasma proteins. Ambroxol is approximately 90% bound to plasma proteins.
MetabolismAcetylcysteine is metabolized in the liver to cysteine, diacetylcysteine, and other metabolites. Ambroxol is metabolized in the liver primarily by glucuronidation and some oxidation.
Half-LifeThe elimination half-life of acetylcysteine is approximately 2-6 hours. The elimination half-life of ambroxol is approximately 7-12 hours.
ExcretionAcetylcysteine and its metabolites are excreted primarily in the urine. Ambroxol and its metabolites are excreted mainly in the urine.
BioavailabilityThe oral bioavailability of acetylcysteine is low (approximately 4-10%) due to extensive first-pass metabolism. The oral bioavailability of ambroxol is approximately 70-80%.
Onset of ActionThe mucolytic effects of this medicine typically begin within 30 minutes to 1 hour after oral administration, but noticeable symptomatic improvement may take 1-2 days of regular use.
Peak Plasma TimePeak plasma concentrations of acetylcysteine are reached approximately 1-2 hours after oral administration. Peak plasma concentrations of ambroxol are reached approximately 1-3 hours after oral administration.
Duration of ActionThe mucolytic effect of a single dose lasts approximately 6-8 hours, but the full therapeutic benefit requires regular dosing as prescribed.

How It Works

This medicine combines two mucoactive agents. Acetylcysteine is a mucolytic that breaks disulfide bonds in mucoproteins, reducing mucus viscosity. Ambroxol is a mucokinetic agent that stimulates serous cell secretion, increases ciliary motility, and promotes surfactant production, thereby enhancing mucus clearance. Together, they thin and mobilize respiratory secretions, making cough more effective.

Mechanism Steps

1
Acetylcysteine breaks disulfide bonds: Acetylcysteine contains a free sulfhydryl group that reduces disulfide bonds in mucin glycoproteins, decreasing mucus viscosity.
2
Ambroxol stimulates serous secretion: Ambroxol increases the production of serous fluid in the airways, which dilutes mucus and makes it less sticky.
3
Ambroxol enhances ciliary motility: Ambroxol increases the beating frequency of cilia, helping to move thinned mucus upward for expulsion.
4
Ambroxol promotes surfactant production: Ambroxol stimulates the production of pulmonary surfactant, which reduces surface tension and aids mucus clearance.
5
Combined effect: improved mucociliary clearance: The combined actions of acetylcysteine and ambroxol result in thinner, less adhesive mucus that is easier to cough up.

💡 How to Take acybronk tablet

Strength: Each immediate-release tablet contains acetylcysteine 200 mg and ambroxol 30 mg.

1Wash your hands before handling the tablet.
2Take the tablet with a full glass of water.
3Swallow the tablet whole; do not crush, chew, or break it.
4Take it with food to reduce stomach upset.
5Follow the dosage schedule prescribed by your doctor.
6Do not take more than the recommended dose.
7If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken two to three times daily, depending on the severity of the condition and your doctor's recommendation. The dose may be adjusted based on your response and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. Take the tablet with a glass of water, preferably with food.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be necessary based on renal and hepatic function. Consult your doctor for appropriate dosing.
Renal ImpairmentIn patients with mild to moderate renal impairment, no dose adjustment is usually necessary. In severe renal impairment, caution is advised and dose reduction may be considered. Consult your doctor.
Hepatic ImpairmentIn patients with mild to moderate hepatic impairment, no dose adjustment is usually necessary. In severe hepatic impairment, caution is advised and dose reduction may be considered. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 2 tablets (i.e., acetylcysteine 400 mg and ambroxol 60 mg) in divided doses, unless otherwise directed by a physician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May increase stomach irritation and nausea.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of acybronk tablet

✅ Common Side Effects

Nausea (Common (1-10%))
Take the tablet with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (1-10%))
Take with a light meal and avoid fatty foods. If vomiting is severe or persistent, contact your doctor.
Stomach discomfort or heartburn (Common (1-10%))
Take with food and avoid lying down immediately after taking the tablet. If symptoms continue, consult your doctor.
Dry mouth (Uncommon (0.1-1%))
Sip water frequently. Chewing sugar-free gum may help.
Altered taste (Uncommon (0.1-1%))
Usually temporary. Rinse your mouth after taking the tablet.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Bronchospasm (Rare (<0.1%))
If you have asthma and experience sudden wheezing or difficulty breathing, stop the medicine and seek emergency care.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek immediate medical attention if you develop a painful rash, blisters, or peeling skin.

⚠️ Rare Side Effects

Headache
Usually resolves on its own. If persistent or severe, consult your doctor.
Dizziness
Avoid driving or operating machinery if you feel dizzy. Consult your doctor if it continues.
Fatigue
Rest and stay hydrated. If fatigue is persistent, consult your doctor.
Runny nose
Usually temporary. Use a tissue and stay hydrated.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Nitroglycerin Major
Codeine Major
Dextromethorphan Major
Amoxicillin Moderate
Cefuroxime Moderate
Tetracycline Moderate
Activated charcoal Minor

🚨 Major Interactions

  • Nitroglycerin
  • Antitussives (e.g., codeine, dextromethorphan)

⚡ Moderate Interactions

  • Antibiotics (e.g., amoxicillin, cefuroxime, tetracycline)
  • Cough suppressants

🍷 Alcohol Interaction

Alcohol may increase the risk of stomach irritation and nausea when taken with this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to acetylcysteine, ambroxol, or any component of the formulation","Active peptic ulcer disease","Children under 12 years of age (unless directed by a physician)","Severe hepatic impairment (relative contraindication)","Severe renal impairment (relative contraindication)"]

⚠️ Warnings & Precautions

["Use with caution in patients with asthma or bronchospasm, as acetylcysteine may rarely cause bronchospasm.","Use with caution in patients with a history of peptic ulcer disease, as acetylcysteine may increase gastric irritation.","Avoid use in patients with phenylketonuria if the formulation contains aspartame (not applicable to this tablet).","Do not use for prolonged periods without medical supervision.","If symptoms persist or worsen after 7 days of treatment, consult a doctor.","The safety and efficacy in children under 12 years have not been established.","Use with caution in elderly patients with renal or hepatic impairment."]

🤱 Lactation Safety

It is not known whether acetylcysteine and ambroxol are excreted in human breast milk. Caution is advised when used by breastfeeding women. Consult your doctor before use.

💊 Overdose Management

Overdose with this medicine may cause nausea, vomiting, and diarrhea. In severe cases, acetylcysteine overdose can lead to bronchospasm, and ambroxol overdose may cause restlessness, tremor, or convulsions. If overdose is suspected, seek immediate medical attention. Treatment is symptomatic and supportive. Activated charcoal may be administered if the patient presents early. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose. Swallow the tablet whole with a glass of water; do not crush or chew it. It is best taken with food to reduce stomach upset. If you have a history of peptic ulcer, asthma, or kidney or liver problems, inform your doctor before taking this medicine. Avoid alcohol while taking this medicine as it may increase stomach irritation. Do not use this medicine for more than the prescribed duration without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to side effects such as dizziness. Dose adjustment may be needed based on renal and hepatic function. Monitor for falls.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Use only if clearly needed.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, especially if you have difficulty coughing or are on other medications.

🦷 Dental Procedures

No specific precautions are known. Inform your dentist if you are taking this medicine.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to add moisture to the air.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Practice deep breathing exercises to help clear lungs.
🧘
Get adequate rest to support recovery.
🌞
Avoid alcohol while taking this medicine.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have difficulty breathing. Gentle activities like walking may help. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Drink plenty of fluids, especially warm water.
Include fruits and vegetables rich in vitamin C.
Avoid dairy products if they seem to thicken mucus.
Reduce intake of processed foods and sugar.
Eat light, easily digestible meals.

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery if you feel dizzy. Otherwise, it usually does not interfere with daily activities.

🛑 When to Stop This Medicine

Stop this medicine and consult your doctor if symptoms worsen or do not improve after 7 days, or if you experience any serious side effects. Do not stop abruptly if you have been on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine beyond the prescribed duration is not recommended without medical supervision. Prolonged use may lead to unnecessary medication exposure. Regular monitoring of symptoms and renal/hepatic function may be needed in patients with underlying conditions.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Can help loosen mucus and ease breathing.

Evidence: Limited
Hydration and humidification

Drinking fluids and using a humidifier can thin mucus.

Evidence: Well-established
Chest physiotherapy

Techniques to help clear secretions from the lungs.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, if you have a respiratory infection, consult your doctor about timing of vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines. Keep enough supply for your trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic bronchitis
Started this medicine as prescribed for chronic bronchitis. Within 2 weeks noticed significant improvement in morning cough and easier expectoration. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old man with COPD
Was prescribed this medicine for thick mucus. After 5 days, he reported easier breathing and less chest congestion. He was advised to continue for 10 days and to avoid alcohol.
💡 Lesson: Regular use and avoiding alcohol can enhance the benefits of this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start to notice thinning of mucus within 30 minutes to 1 hour, but full benefits may take 1-2 days of regular use.

Q: Can I take this medicine with antibiotics?

A: Yes, but ambroxol may increase antibiotic levels in the lungs. This is often beneficial, but inform your doctor.

Q: Is it safe during pregnancy?

A: Consult your doctor. Use only if clearly needed.

Q: Can I take it for a dry cough?

A: No, this medicine is for cough with thick mucus. It is not effective for dry cough.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for acybronk tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is only for cough with thick mucus. It is not effective for dry cough or cough due to allergies.
  • Myth: It is safe to take this medicine for a long time without doctor supervision.
    Fact: Prolonged use without medical supervision is not recommended. Consult your doctor if symptoms persist beyond 7 days.
  • Myth: This medicine can be taken with cough syrups that suppress cough.
    Fact: Combining with cough suppressants may prevent mucus clearance and should be avoided unless directed by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Acetylcysteine + Ambroxol combination tablets from other manufacturers

Brand Alternatives

  • Acybronk Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Acetylcysteine + Ambroxol","composition":"Acetylcysteine 200 mg + Ambroxol 30 mg","key_feature":"Dual-action mucolytic and mucokinetic"},{"medicine":"Acetylcysteine alone","composition":"Acetylcysteine 200 mg or 600 mg","key_feature":"Mucolytic only"},{"medicine":"Ambroxol alone","composition":"Ambroxol 30 mg","key_feature":"Mucokinetic and secretolytic"},{"medicine":"Carbocisteine","composition":"Carbocisteine 375 mg or 500 mg","key_feature":"Mucolytic, reduces mucus viscosity"}]

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