Acupime TZ 250mg/31.25mg Injection: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe or bloody diarrhea
- Seizures or confusion
- Decreased urine output or swelling in the legs
- Severe skin rash with peeling or blisters
- Persistent high fever despite treatment
If experiencing severe symptoms, call emergency services immediately.
What is acupime tz 250mg/31.25mg injection used for?
This medicine is a combination antibiotic injection containing cefepime and tazobactam. It is used to treat serious bacterial infections in hospitals. It works by killing bacteria and is given by a healthcare professional.
- Generic Name: Cefepime (250mg) + Tazobactum (31.25mg)
- Manufacturer: Alive Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acupime tz 250mg/31.25mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा एक संयुक्त एंटीबायोटिक इंजेक्शन है जिसमें सेफेपाइम और टैज़ोबैक्टम शामिल हैं। इसका उपयोग अस्पताल में गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है, जैसे कि मूत्र मार्ग संक्रमण, पेट के संक्रमण, त्वचा संक्रमण और निमोनिया। यह दवा बैक्टीरिया को मारकर काम करती है और इसे डॉक्टर या नर्स द्वारा इंजेक्शन के रूप में दिया जाता है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, लालिमा या सूजन, दस्त, जी मिचलाना, उल्टी, सिरदर्द, दाने और बुखार शामिल हो सकते हैं। गंभीर दुष्प्रभाव कम होते हैं, लेकिन एलर्जी, गंभीर दस्त, दौरे, गुर्दे की समस्या या रक्त विकार हो सकते हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्यकर्मी द्वारा अस्पताल या क्लिनिक में ही दी जानी चाहिए। इससे पहले कि आपको यह दवा दी जाए, अपने डॉक्टर को अपनी सभी एलर्जी, गुर्दे या लीवर की समस्या, दौरे का इतिहास और अन्य दवाओं के बारे में बताएं। इसे स्वयं न लगाएं। कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। गंभीर दस्त, दाने, सूजन या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर को सूचित करें। इलाज के दौरान शराब न पिएं।
💊 acupime tz 250mg/31.25mg injection Uses & Benefits
[{"condition":"Complicated urinary tract infections","description":"Used to treat serious kidney and bladder infections caused by susceptible bacteria when oral therapy is not suitable.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Prescribed for complicated abdominal infections, often in combination with other antibiotics or surgical drainage.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for severe skin infections, including cellulitis and abscesses, when caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Pneumonia","description":"Treats moderate to severe community-acquired or hospital-acquired pneumonia caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"Empirically used in patients with fever and low white blood cell counts to cover a broad range of bacteria.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Bone and joint infections","description":"Occasionally used for osteomyelitis or septic arthritis when susceptible bacteria are identified.","evidence":"Limited"},{"condition":"Meningitis","description":"May be used in some cases of bacterial meningitis, though other agents are often preferred.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Complicated urinary tract infections, Intra-abdominal infections, Skin and soft tissue infections, Pneumonia, Febrile neutropenia
📋 Drug Information
| Generic Name(s) | Cefepime (250mg) + Tazobactum (31.25mg) |
| Brand Name | acupime tz 250mg/31.25mg injection |
| Manufacturer | Alive Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Parenteral (intravenous or intramuscular injection) |
| Storage | Store the unreconstituted powder at room temperature between 20°C and 25°C (68°F to 77°F). Protect from light and moisture. Once reconstituted, the solution should be used within the time specified by the manufacturer, typically within a few hours if stored at room temperature or up to 24 hours if refrigerated. Follow the specific instructions provided with the product. |
| Shelf Life | The shelf life of the unreconstituted product is typically 24 months from the date of manufacture. Check the expiration date on the packaging. Do not use if expired. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefepime, the primary active component, is a fourth-generation cephalosporin that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial cell death. Tazobactam is a beta-lactamase inhibitor that protects cefepime from degradation by certain beta-lactamase enzymes produced by resistant bacteria. Together, they broaden the spectrum of activity against many gram-positive and gram-negative organisms.
Mechanism Steps
💡 How to Take acupime tz 250mg/31.25mg injection
Strength: Injection: Cefepime 250 mg + Tazobactam 31.25 mg per vial.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the type and severity of infection, the patient's kidney function, and other factors. Typical adult doses for cefepime range from 1 gram to 2 grams every 8 to 12 hours, but the specific dose for this 250 mg/31.25 mg presentation will be determined by your doctor. It is given by intravenous or intramuscular injection. Do not self-administer. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific combination and strength. Consult a pediatrician for appropriate dosing. |
| Elderly Dosage | Elderly patients may have reduced kidney function and may require lower doses. Dose adjustment should be based on renal function. Monitor closely for neurological side effects. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. The dose and/or dosing interval should be modified based on creatinine clearance. Consult a healthcare professional for specific guidance. |
| Hepatic Impairment | No specific dose adjustment is typically required for hepatic impairment, as cefepime is primarily renally excreted. However, monitor liver function in patients with pre-existing liver disease. |
| Maximum Daily Dose | The maximum daily dose should not exceed the recommended limits set by a qualified clinician. For cefepime, the usual maximum is 6 grams per day, but this may vary based on the clinical situation and renal function. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acupime tz 250mg/31.25mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aminoglycosides | Major | |
| Loop diuretics | Major | |
| Warfarin | Major | |
| Probenecid | Moderate | |
| Other beta-lactams | Moderate |
🚨 Major Interactions
- Aminoglycosides (e.g., gentamicin)
- Loop diuretics (e.g., furosemide)
- Warfarin
⚡ Moderate Interactions
- Probenecid
- Other beta-lactam antibiotics
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine because it may increase the risk of stomach upset, dizziness, and may worsen the underlying infection. It can also add to liver stress if you are taking other medications.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe hypersensitivity to cefepime, tazobactam, or other beta-lactam antibiotics","Previous anaphylactic reaction to penicillins or cephalosporins","Use in patients with known severe renal impairment without dose adjustment"]
⚠️ Warnings & Precautions
["Serious allergic reactions, including anaphylaxis, can occur. Discontinue immediately if suspected.","Clostridioides difficile-associated diarrhea may develop during or after treatment.","Seizures have been reported, particularly in patients with renal impairment or underlying CNS disorders.","Dose adjustment is required in patients with reduced kidney function.","Prolonged use may lead to superinfection with non-susceptible organisms.","Monitor renal, hepatic, and hematologic function during therapy.","Use with caution in patients with a history of gastrointestinal disease, especially colitis."]
🤱 Lactation Safety
Cefepime and tazobactam are excreted in low amounts in breast milk. Caution is advised; consult your doctor before breastfeeding while on this medicine. Monitoring the infant for diarrhea or thrush may be prudent.
💊 Overdose Management
Overdose with this medicine is unlikely in a clinical setting. If suspected, treatment should be symptomatic and supportive. Cefepime and tazobactam can be removed by hemodialysis. Contact a poison control center or emergency department immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose of this medicine, inform your healthcare provider as soon as possible. Do not attempt to self-administer a double dose. Your doctor will determine the appropriate schedule.
Additional Safety Advice
This medicine must be administered only by a qualified healthcare professional in a clinical setting. Before receiving this medicine, inform your doctor about all your allergies, especially to antibiotics, and about any kidney or liver problems, seizure history, or gastrointestinal conditions. Do not attempt to self-administer this injection. Complete the full course as prescribed, even if you feel better, to reduce the risk of resistance. Report severe diarrhea, rash, swelling, or difficulty breathing immediately. Your doctor may monitor your kidney function, blood counts, and liver enzymes during treatment. Avoid alcohol during therapy as it may worsen side effects. Keep all follow-up appointments and do not share this medicine with anyone else.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function and may require lower doses. They are also at higher risk of neurological side effects like confusion and seizures. Close monitoring of kidney function and neurological status is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before starting this medicine. It is generally considered safe when needed, but the benefits should outweigh the risks. Use effective contraception if advised. If you become pregnant while on this medicine, inform your doctor immediately.
🏥 Post-Surgery Considerations
This medicine is often used to prevent or treat infections after surgery. It is important to complete the prescribed course to prevent surgical site infections. Monitor the surgical wound for redness, swelling, or discharge and report any concerns to your surgeon.
🦷 Dental Procedures
If you are scheduled for dental work, inform your dentist that you are receiving this medicine. It may be used to prevent infection in certain dental procedures, but usually not required. Your dentist may consult with your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While receiving this medicine, you may feel tired or dizzy. Avoid strenuous exercise until you feel fully recovered. Light activity like walking is fine if you feel up to it. Consult your doctor before resuming intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or clinic, so you may need to take time off work or arrange for transportation. You may experience fatigue, dizziness, or diarrhea, which can affect your ability to work. Avoid driving or operating machinery if you feel dizzy. Discuss with your employer about sick leave if needed.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping early can lead to incomplete treatment and resistance. Your doctor will determine when to stop based on your clinical response and test results. If you experience severe side effects, contact your doctor immediately; they will decide whether to stop or change the treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of antibiotic resistance, superinfections, and Clostridioides difficile-associated diarrhea. Prolonged therapy may also affect kidney function and blood counts. Regular monitoring is advised if extended treatment is necessary. Usually, this medicine is used for a short duration, and long-term effects are not common when used appropriately.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For less severe infections, oral antibiotics may be used instead of injections.
Evidence: Well-establishedDepending on the bacteria and sensitivity, other antibiotics like piperacillin-tazobactam or meropenem may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are due for any vaccinations, inform your doctor. Live vaccines should be avoided during acute infection. There is no specific contraindication, but timing should be discussed with your healthcare provider.
📦 Storage Guide
✅ DO
Store the unreconstituted powder at room temperature (20-25°C).
❌ DON'T
Do not freeze the powder.
✅ DO
Protect from light and moisture.
❌ DON'T
Do not store in the bathroom.
✅ DO
Use reconstituted solution within the recommended time.
❌ DON'T
Do not use if the solution is cloudy or contains particles.
✈️ Traveling with This Medicine
If you need to travel while receiving this medicine, it is usually administered in a healthcare setting, so travel may be limited. If you are discharged with a prescription for home infusion, carry the medicine in its original packaging with the prescription label. Keep it at the recommended temperature using a cooler pack if necessary. Carry a copy of your prescription and a letter from your doctor explaining the medical need. Check with airlines and customs about carrying injectable medications. Plan your doses around travel schedules and ensure you have enough supply.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24-48 hours, but it may take a few days for full effect. Complete the full course as prescribed.
A: No, this medicine is given by a healthcare professional in a clinic or hospital setting. It is not for self-administration.
A: If you miss a dose, inform your healthcare provider immediately. Do not try to double the dose.
A: No specific food restrictions, but avoid alcohol during treatment.
🤔 Common Patient Concerns
🔄 Substitutes for acupime tz 250mg/31.25mg injection
View AllAlternative brands with exact same active ingredient:
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atracef t 250mg/31.25mg injectionAshlife Healthcare ₹80.00 19.6% CHEAPER
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Forthcef TZ 250mg/31.25mg InjectionRidhima Biocare ₹80.00 19.6% CHEAPER
-
cefe well t 250mg/31.25mg injectionEverwell Pharma Pvt Ltd ₹82.50 17.1% CHEAPER
-
dxpime tz 250mg/31.25mg injectionDoux Healthcare Pvt Ltd ₹83.44 16.1% CHEAPER
-
genpime 250mg/31.25mg injectionPlus India ₹84.37 15.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and only works against bacterial infections. It is not effective against viruses. - Myth: You can stop the injection once you feel better.
Fact: You must complete the full course as prescribed by your doctor to prevent the infection from returning and to reduce resistance. - Myth: This medicine is safe to self-administer at home.
Fact: This medicine must be given by a trained healthcare professional in a clinical setting. Self-administration is not recommended.
🔄 Alternative Options
Generic Alternatives
- Cefepime + Tazobactam injection (generic versions may be available)
Brand Alternatives
- Acupime TZ 250mg/31.25mg injection