acronicol suspension

4.5 (14 reviews)

Chloramphenicol (125mg)

🏭 Acron Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is acronicol suspension used for?

Andrecin Eye Drop (Chloramphenicol) is used to treat OTOLOGICALS. It contains Chloramphenicol (125mg), which Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, pr. Always consult your doctor before use. Take as prescribed.

Generic Name: Chloramphenicol
Manufacturer: Acron Pharmaceuticals
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 acronicol suspension Uses & Benefits

Treatment of bacterial conjunctivitis, keratitis, and other superficial ocular infections.

Off-label uses: Prophylaxis in ocular surgery; treatment of blepharitis.

📋 Drug Information

Generic Name(s)	Chloramphenicol
Brand Name	Andrecin Eye Drop
Manufacturer	Acron Pharmaceuticals
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	OTOLOGICALS
Action Class	Chloramphenicol
Route of Administration	Topical ophthalmic (eye drops).
Storage	Store at 15-30°C (59-86°F); protect from light; keep bottle tightly closed.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed into the aqueous humor after topical ocular administration.

DistributionDistributes into ocular tissues; systemic absorption minimal with topical use.

Protein BindingApproximately 50-60% bound to plasma proteins.

MetabolismPrimarily hepatic via glucuronidation; active metabolite not significant.

Half-Life1.5-3.5 hours (systemic); topical ocular half-life not well defined.

ExcretionRenal excretion of metabolites and unchanged drug.

BioavailabilityLow systemic bioavailability due to topical administration.

Onset of ActionRapid; within 30 minutes after topical application.

Peak Plasma TimeNot applicable for topical use; minimal systemic levels.

Duration of ActionApproximately 6-8 hours after topical application.

How It Works

Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation.

Mechanism Steps

1Chloramphenicol enters bacterial cell via diffusion.

2Binds reversibly to the 50S ribosomal subunit.

3Inhibits peptidyl transferase activity.

💡 How to Take acronicol suspension

Follow your doctor's prescription exactly.

⚠️ Side Effects of acronicol suspension

✅ Common Side Effects

Transient stinging or burning
Blurred vision
Eye irritation
Redness

🚨 Serious Side Effects

Bone marrow suppression (aplastic anemia)
Gray baby syndrome (systemic use in neonates)
Hypersensitivity reactions

⚠️ Rare Side Effects

Optic neuritis
Peripheral neuropathy
Superinfection with resistant organisms

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk due to inhibition of warfarin metabolism.
Phenytoin	Major	Increased phenytoin levels and toxicity.
Phenobarbital	Major	Decreased chloramphenicol levels.
Rifampin	Major	Decreased chloramphenicol efficacy.
Oral contraceptives	Moderate	Reduced contraceptive efficacy.
Cyclosporine	Moderate	Increased cyclosporine levels.
Tacrolimus	Moderate	Increased tacrolimus levels.
Acetaminophen	Minor	Possible additive hepatotoxicity.
Cimetidine	Minor	Increased chloramphenicol levels.

🚨 Major Interactions

Warfarin
Phenytoin
Phenobarbital
Rifampin

⚡ Moderate Interactions

Oral contraceptives
Cyclosporine
Tacrolimus

ℹ️ Minor Interactions

Acetaminophen
Cimetidine

🍽️ Food Interactions

No significant food interactions reported.

🍷 Alcohol Interaction

Avoid alcohol; may increase risk of hepatotoxicity.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to chloramphenicol; history of bone marrow depression; systemic use in neonates and pregnancy (third trimester).

📊 Monitoring Parameters

Monitor for signs of hypersensitivity, bone marrow suppression (rare with topical use), and superinfection.

🤱 Lactation Safety

Caution; small amounts excreted in breast milk, but topical use unlikely to cause significant exposu

💊 Overdose Management

Topical overdose unlikely; if ingested, induce vomiting or gastric lavage; monitor for bone marrow suppression.

⏰ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for acronicol suspension

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Alternative brands with exact same active ingredient (Chloramphenicol (125mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.