acq xl 100mg/50mg tablet - Aceclofenac (100mg) + Diacerein (50mg) medicine

acq xl 100mg/50mg tablet

4.5 (8 reviews)
๐Ÿญ Globus Labs ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is acq xl 100mg/50mg tablet used for?

Accept-XL Tablet (Aceclofenac + Diacerein) is used to treat PAIN ANALGESICS. It contains Aceclofenac (100mg) + Diacerein (50mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Diacerei. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aceclofenac + Diacerein
  • Manufacturer: Globus Labs
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š acq xl 100mg/50mg tablet Uses & Benefits

Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis

Off-label uses: Acute gout, soft tissue injuries

๐Ÿ“‹ Drug Information

Generic Name(s)Aceclofenac + Diacerein
Brand NameAccept-XL Tablet
ManufacturerGlobus Labs
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Anthraquinone derivative
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture and light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in body tissues
Protein BindingAceclofenac: >99%; Diacerein: ~99%
MetabolismAceclofenac: hepatic via CYP2C9; Diacerein: deacetylated to rhein
Half-LifeAceclofenac: 4-5 hours; Diacerein: 7-8 hours
ExcretionRenal (primarily) and fecal
BioavailabilityAceclofenac: ~100%; Diacerein: ~56%
Onset of ActionAceclofenac: 1-2 hours; Diacerein: 2-4 weeks
Peak Plasma TimeAceclofenac: 1-3 hours; Diacerein: 2-4 hours
Duration of ActionAceclofenac: 12 hours; Diacerein: 24 hours

How It Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Diacerein inhibits IL-1ฮฒ and stimulates TGF-ฮฒ, modulating cartilage metabolism

Mechanism Steps

1Aceclofenac inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing conversion of arachidonic acid to prostaglandins, thromboxanes, and prostacyclin, thereby decreasing inflammation and pain.
2Diacerein inhibits interleukin-1 beta (IL-1ฮฒ) production and activity, reducing cartilage degradation and stimulating transforming growth factor-beta (TGF-ฮฒ) to promote cartilage repair.

๐Ÿ’ก How to Take acq xl 100mg/50mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of acq xl 100mg/50mg tablet

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Abdominal pain
  • Dyspepsia
  • Headache
  • Dizziness

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatotoxicity
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Anaphylaxis
  • Pancreatitis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Lithium Major Increased lithium toxicity
Methotrexate Major Increased methotrexate toxicity
Anticoagulants Major Enhanced anticoagulant effect
Aspirin Major Increased GI ulceration risk
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
Corticosteroids Moderate Increased GI ulceration risk
Cyclosporine Moderate Increased nephrotoxicity
Antacids Minor Reduced absorption of diacerein
Cholestyramine Minor Reduced absorption of diacerein

๐Ÿšจ Major Interactions

  • Warfarin
  • Lithium
  • Methotrexate
  • Anticoagulants
  • Aspirin

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Corticosteroids
  • Cyclosporine

โ„น๏ธ Minor Interactions

  • Antacids
  • Cholestyramine

๐Ÿฝ๏ธ Food Interactions

May be taken with food to reduce GI upset; avoid high-fat meals as may delay absorption

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to components, active peptic ulcer, severe hepatic/renal impairment, pregnancy (third trimester), inflammatory bowel disease

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, blood pressure, signs of GI bleeding

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage if recent; monitor renal and hepatic function

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

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