acnac 200mg tablet sr - Aceclofenac (200mg) medicine

acnac 200mg tablet sr - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Axodin Pharmaceuticals Pvt. Ltd. ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is acnac 200mg tablet sr used for?

Aceclo Tablet (Aceclofenac) is used to treat PAIN ANALGESICS. It contains Aceclofenac (200mg), which Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthe. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aceclofenac
  • Manufacturer: Axodin Pharmaceuticals Pvt. Ltd.
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š acnac 200mg tablet sr Uses & Benefits

Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute musculoskeletal pain, dental pain, dysmenorrhea.

Off-label uses: Fever, gout, migraine, postoperative pain.

๐Ÿ“‹ Drug Information

Generic Name(s)Aceclofenac
Brand NameAceclo Tablet
ManufacturerAxodin Pharmaceuticals Pvt. Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Route of AdministrationOral.
StorageStore at room temperature (15-30ยฐC), protected from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration achieved within 1.25-3 hours.
DistributionWidely distributed; crosses the placenta and enters breast milk.
Protein Binding>99% bound to plasma proteins, primarily albumin.
MetabolismPrimarily hepatic via CYP2C9 to active metabolite 4-hydroxyaceclofenac; also undergoes conjugation.
Half-LifeApproximately 4 hours (range 3-6 hours).
ExcretionApproximately 70% renal (as metabolites) and 30% fecal.
BioavailabilityApproximately 100% (oral).
Onset of ActionWithin 30 minutes to 1 hour.
Peak Plasma Time1.25-3 hours.
Duration of ActionUp to 12 hours.

How It Works

Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis.

Mechanism Steps

1Aceclofenac binds to COX-1 and COX-2 enzymes.
2Inhibits conversion of arachidonic acid to prostaglandin H2.
3Reduces synthesis of prostaglandins (PGE2, PGI2, etc.).

๐Ÿ’ก How to Take acnac 200mg tablet sr

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of acnac 200mg tablet sr

โœ… Common Side Effects

  • Nausea
  • Dyspepsia
  • Abdominal pain
  • Diarrhea
  • Headache
  • Dizziness
  • Rash

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatitis
  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Cardiovascular thrombotic events

โš ๏ธ Rare Side Effects

  • Pancreatitis
  • Aplastic anemia
  • Agranulocytosis
  • Toxic epidermal necrolysis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Major Increased risk of GI ulceration and bleeding
Lithium Major Increased lithium levels and toxicity
Methotrexate Major Increased methotrexate toxicity
Anticoagulants Major Enhanced anticoagulant effect
Corticosteroids Major Increased risk of GI ulceration
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
Cyclosporine Moderate Increased nephrotoxicity
Tacrolimus Moderate Increased nephrotoxicity
SSRIs Moderate Increased bleeding risk
Antacids Minor Slight delay in absorption
Cholestyramine Minor Reduced absorption

๐Ÿšจ Major Interactions

  • Warfarin
  • Aspirin
  • Lithium
  • Methotrexate
  • Anticoagulants
  • Corticosteroids

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Cyclosporine
  • Tacrolimus
  • SSRIs

โ„น๏ธ Minor Interactions

  • Antacids
  • Cholestyramine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not significantly affect overall bioavailability.

๐Ÿท Alcohol Interaction

Increased risk of gastrointestinal bleeding and ulcers.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to aceclofenac or other NSAIDs; active peptic ulcer; history of GI bleeding; severe heart failure; renal failure; third trimester pregnancy.

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, blood pressure, signs of GI bleeding, CBC (for long-term use).

๐Ÿคฑ Lactation Safety

Excreted in breast milk; avoid use or discontinue breastfeeding.

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal; monitor for GI bleeding, renal failure, and CNS depression.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for acnac 200mg tablet sr

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Alternative brands with exact same active ingredient (Aceclofenac (200mg)):

Medical Note: Always consult your doctor before switching medications.

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