Acfast Gel (Serratiopeptidase): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is acfast gel used for?
This medicine contains serratiopeptidase, an enzyme that reduces inflammation and swelling by breaking down fibrin. It is used for post-surgical edema, traumatic swelling, and inflammatory conditions.
- Generic Name: Serratiopeptidase
- Manufacturer: Kim Lab
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acfast gel के बारे में (Hindi Summary)
उपयोग: यह दवा सूजन और दर्द को कम करने के लिए उपयोग की जाती है। यह सर्जरी के बाद की सूजन, चोट के कारण होने वाली सूजन और अन्य सूजन संबंधी स्थितियों में प्रभावी है। यह एंजाइम सूजन पैदा करने वाले प्रोटीन को तोड़कर काम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट में असुविधा और भूख में कमी शामिल हो सकती है। कुछ रोगियों में एलर्जी प्रतिक्रियाएं जैसे त्वचा पर चकत्ते, खुजली या पित्ती हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन गंभीर एलर्जी प्रतिक्रिया, रक्तस्राव या यकृत एंजाइम असामान्यताएं हो सकती हैं।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक या अवधि से अधिक न लें। यदि आपको रक्तस्राव विकार, यकृत रोग या गुर्दा रोग का इतिहास है तो अपने डॉक्टर को सूचित करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर की सलाह के बिना इसका उपयोग न करें।
💊 acfast gel Uses & Benefits
[{"condition":"Post-surgical edema","description":"Reduces inflammation" class="semantic-link" title="Medicines for swelling">swelling and inflammation after surgical procedures, promoting faster recovery.","evidence":"Moderate"},{"condition":"Traumatic swelling","description":"Helps in reducing swelling and pain associated with injuries and trauma.","evidence":"Moderate"},{"condition":"Inflammatory conditions","description":"Used as an adjunct in various inflammatory conditions to reduce edema and pain.","evidence":"Limited"}]
Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used off-label to reduce inflammation and congestion in sinusitis.","evidence":"Limited"},{"condition":"Bronchitis","description":"May be used off-label to help reduce mucus viscosity and inflammation in bronchitis.","evidence":"Limited"}]
Primary treatment for: Inflammation and edema
Also treats: Post-surgical swelling, Traumatic swelling, Sinusitis, Bronchitis
📋 Drug Information
| Generic Name(s) | Serratiopeptidase |
| Brand Name | Ace 15mg Tablet |
| Manufacturer | Kim Lab |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Proteolytic Enzymes |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Serratiopeptidase is a proteolytic enzyme that hydrolyzes peptide bonds in proteins. It breaks down fibrin, a protein involved in blood clotting and inflammation, thereby reducing swelling and edema. It also helps in thinning mucus, making it easier to expel. The enzyme exhibits anti-inflammatory, anti-edematous, and fibrinolytic properties.
Mechanism Steps
💡 How to Take acfast gel
Strength: Oral gel (strength not specified)
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5-10 mg taken orally two to three times daily, depending on the condition being treated. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal and hepatic function. Consult your doctor. |
| Renal Impairment | Dose adjustment may be needed in patients with severe renal impairment. Consult your doctor. |
| Hepatic Impairment | Dose adjustment may be needed in patients with severe hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 30 mg, but this may vary based on clinical judgment. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acfast gel
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Moderate | |
| Clopidogrel | Moderate |
🚨 Major Interactions
- Anticoagulants (e.g., warfarin)
⚡ Moderate Interactions
- Antiplatelet drugs (e.g., aspirin)
🍷 Alcohol Interaction
Alcohol may increase the risk of gastrointestinal side effects. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to serratiopeptidase","Active bleeding disorders","Concurrent use with anticoagulants"]
⚠️ Warnings & Precautions
["Use with caution in patients with bleeding disorders.","Avoid in patients with known hypersensitivity.","Consult doctor before use in pregnancy and lactation.","Do not exceed recommended dose.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether serratiopeptidase is excreted in human milk. Consult your doctor before use.
💊 Overdose Management
Overdose may cause increased side effects. Seek immediate medical attention if you suspect an overdose. Treatment is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Inform your doctor if you have a history of bleeding disorders, liver disease, or kidney disease. Avoid using this medicine if you are pregnant or breastfeeding unless advised by your doctor. Do not take this medicine with other anti-inflammatory drugs without consulting your doctor. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects. Dose adjustment may be needed based on renal and hepatic function.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy while on this medicine. The safety profile in pregnancy is not well-established.
🏥 Post-Surgery Considerations
This medicine is often prescribed post-surgery to reduce swelling and promote healing. Follow your surgeon's instructions carefully.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may affect bleeding during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you have swelling or pain. Gentle stretching and low-impact activities are recommended. Consult your doctor before starting any exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some individuals. Avoid driving or operating heavy machinery if you experience these effects.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects or if your symptoms worsen. Do not stop abruptly without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may require monitoring of liver function and bleeding parameters. It is generally well-tolerated, but prolonged use should be under medical supervision. Regular follow-ups are advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedHelps reduce swelling and pain.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme temperatures. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts working within 30 minutes to 1 hour after oral administration, with peak effects in 1-2 hours.
A: Consult your doctor before combining with other painkillers, as interactions may occur.
🤔 Common Patient Concerns
🔄 Substitutes for acfast gel
View AllAlternative brands with exact same active ingredient:
-
acfast injectionKim Lab ₹7.61 65.8% CHEAPER
-
seretochem forte tabletBiochem Pharmaceutical Industries ₹10.00 55.1% CHEAPER
-
kodanzen forte tabletKopran Ltd ₹11.72 47.4% CHEAPER
-
septidase tabletMMC Healthcare Ltd ₹28.87 29.6% COSTLIER
-
sericon d tabletConcept Pharmaceuticals Ltd ₹44.63 100.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller.
Fact: This medicine is an anti-inflammatory enzyme, not a painkiller. It reduces swelling and inflammation. - Myth: This medicine can be used for any type of pain.
Fact: This medicine is specifically for inflammatory conditions and edema, not for all types of pain.
🔄 Alternative Options
Generic Alternatives
- Serratiopeptidase 5 mg
- Serratiopeptidase 10 mg
Brand Alternatives
- Serratiopeptidase (various brands)