acezon t 37.5mg/325mg tablet - Tramadol (37.5mg) + Paracetamol (325mg) medicine

acezon t 37.5mg/325mg tablet

4.3 (12 reviews)
๐Ÿญ Maxnova Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is acezon t 37.5mg/325mg tablet used for?

Anadol P (Tramadol + Paracetamol) is used to treat PAIN ANALGESICS. It contains Tramadol (37.5mg) + Paracetamol (325mg), which Tramadol: Binds to mu-opioid receptors and inhibits serotonin/norepinephrine reu. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Tramadol + Paracetamol
  • Manufacturer: Maxnova Healthcare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š acezon t 37.5mg/325mg tablet Uses & Benefits

Moderate to severe pain, acute pain, postoperative pain

Off-label uses: Chronic pain, neuropathic pain

๐Ÿ“‹ Drug Information

Generic Name(s)Tramadol + Paracetamol
Brand NameAnadol P
ManufacturerMaxnova Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassOpioid analgesic + Non-opioid analgesic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract
DistributionWidely distributed; crosses placenta and blood-brain barrier
Protein BindingTramadol: ~20%; Paracetamol: ~10-25%
MetabolismTramadol: Hepatic via CYP2D6 and CYP3A4 to active metabolite O-desmethyltramadol; Paracetamol: Hepatic via glucuronidation and sulfation
Half-LifeTramadol: 5-7 hours; Paracetamol: 1.5-2.5 hours
ExcretionRenal (tramadol and metabolites); Renal (paracetamol metabolites)
BioavailabilityTramadol: ~75%; Paracetamol: ~88%
Onset of ActionTramadol: 30-60 minutes; Paracetamol: 30-60 minutes
Peak Plasma TimeTramadol: 1-2 hours; Paracetamol: 0.5-1 hour
Duration of ActionTramadol: 4-6 hours; Paracetamol: 4-6 hours

How It Works

Tramadol: Binds to mu-opioid receptors and inhibits serotonin/norepinephrine reuptake; Paracetamol: Inhibits COX enzymes in the CNS, reducing prostaglandin synthesis

Mechanism Steps

1Tramadol binds to mu-opioid receptors in the CNS, inhibiting pain transmission
2Tramadol inhibits serotonin and norepinephrine reuptake, enhancing descending pain modulation
3Paracetamol inhibits COX enzymes in the CNS, reducing prostaglandin synthesis and pain perception

๐Ÿ’ก How to Take acezon t 37.5mg/325mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of acezon t 37.5mg/325mg tablet

โœ… Common Side Effects

  • Nausea
  • Dizziness
  • Drowsiness
  • Constipation
  • Headache
  • Sweating

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • Seizures
  • Serotonin syndrome
  • Hepatotoxicity
  • Hypotension

โš ๏ธ Rare Side Effects

  • QT prolongation
  • Adrenal insufficiency
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Risk of serotonin syndrome
SSRIs Major Increased serotonin levels, risk of serotonin syndrome
Warfarin Moderate Increased INR and bleeding risk
Alcohol Moderate Enhanced CNS depression and hepatotoxicity

๐Ÿšจ Major Interactions

  • MAOIs
  • SSRIs
  • SNRIs
  • TCAs
  • CNS depressants
  • Carbamazepine
  • Rifampin

โšก Moderate Interactions

  • Warfarin
  • Anticoagulants
  • Alcohol
  • Antiepileptics
  • CYP2D6 inhibitors

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Metoclopramide

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; avoid grapefruit juice (CYP3A4 inhibition)

๐Ÿท Alcohol Interaction

Increased CNS depression and hepatotoxicity risk

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, acute opioid intoxication, severe respiratory depression, MAOI use within 14 days, severe hepatic impairment

๐Ÿ“Š Monitoring Parameters

Pain relief, respiratory rate, liver function, renal function, signs of serotonin syndrome

๐Ÿคฑ Lactation Safety

Use with caution; tramadol excreted in breast milk

๐Ÿ’Š Overdose Management

Naloxone for tramadol; N-acetylcysteine for paracetamol; supportive care

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

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