acetomef oral suspension - Uses, Price, Side Effects & Substitutes
What is acetomef oral suspension used for?
Abmef-DS Oral Suspension (Mefenamic Acid + Paracetamol) is used to treat PAIN ANALGESICS. It contains Mefenamic Acid (50mg) + Paracetamol (125mg), which Mefenamic acid inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin syn. Always consult your doctor before use. Take as prescribed.
- Generic Name: Mefenamic Acid + Paracetamol
- Manufacturer: Adept Biocare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acetomef oral suspension Uses & Benefits
๐ Drug Information
| Generic Name(s) | Mefenamic Acid + Paracetamol |
| Brand Name | Abmef-DS Oral Suspension |
| Manufacturer | Adept Biocare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Nonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Mefenamic acid inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis; Paracetamol inhibits COX in the central nervous system and modulates pain perception.
Mechanism Steps
๐ก How to Take acetomef oral suspension
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of acetomef oral suspension
โ Common Side Effects
- Nausea
- Vomiting
- Dyspepsia
- Diarrhea
- Dizziness
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Hepatotoxicity
- Renal failure
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Thrombocytopenia
- Pancreatitis
- Aplastic anemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels |
| Aspirin | Major | Increased GI ulceration risk |
| Alcohol | Major | Hepatotoxicity and GI bleeding |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic effect |
| Anticoagulants | Moderate | Increased bleeding risk |
| SSRIs | Moderate | Increased bleeding risk |
| Antacids | Minor | Reduced absorption of mefenamic acid |
| Cholestyramine | Minor | Reduced absorption of mefenamic acid |
| Oral contraceptives | Minor | Possible reduced contraceptive efficacy |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Lithium
- Aspirin
- Alcohol
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- SSRIs
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of hepatotoxicity (paracetamol) and GI bleeding (mefenamic acid).
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy.
๐ Monitoring Parameters
Liver function, renal function, CBC, signs of GI bleeding.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for mefenamic acid.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double.