Acethromb 1mg Tablet - Uses, Price, Side Effects
What is acethromb 1mg tablet used for?
Acethromb 1mg Tablet contains Acenocoumarol, an anticoagulant that prevents blood clots by inhibiting vitamin K-dependent clotting factors. It is used to treat and prevent deep vein thrombosis, pulmonary embolism, and stroke in patients with atrial fibrillation or heart valve replacements.
- Generic Name: Acenocoumarol
- Manufacturer: Suvik Hitek Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acethromb 1mg tablet Uses & Benefits
Prophylaxis and treatment of venous thromboembolism, Prevention of thromboembolism in atrial fibrillation, Prophylaxis after heart valve replacement, Treatment of pulmonary embolism
Off-label uses: Prevention of recurrent myocardial infarction, Antiphospholipid syndrome
๐ Drug Information
| Generic Name(s) | Acenocoumarol |
| Brand Name | Acitrom 2 Tablet |
| Manufacturer | Suvik Hitek Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Vitamin K antagonists |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits vitamin K epoxide reductase, preventing activation of vitamin K-dependent clotting factors (II, VII, IX, X) and anticoagulant proteins C and S.
Mechanism Steps
๐ก How to Take acethromb 1mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of acethromb 1mg tablet
โ Common Side Effects
- Bleeding (e.g., epistaxis, bruising, gum bleeding)
- Nausea
- Diarrhea
- Abdominal pain
- Alopecia
๐จ Serious Side Effects
- Major hemorrhage (e.g., intracranial, gastrointestinal)
- Skin necrosis
- Purple toes syndrome
- Hepatic injury
โ ๏ธ Rare Side Effects
- Calciphylaxis
- Tracheobronchial calcification
- Pancreatitis
- Priapism
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Aspirin | Major | Increased bleeding risk |
| NSAIDs | Major | Increased bleeding risk |
| Antibiotics | Moderate | Altered anticoagulant effect |
๐จ Major Interactions
- Warfarin
- Aspirin
- NSAIDs
- Heparin
- Clopidogrel
- Rifampin
- Phenytoin
- Cimetidine
- Metronidazole
- Fluconazole
โก Moderate Interactions
- Amiodarone
- Statins
- SSRIs
- Omeprazole
- Allopurinol
- Oral contraceptives
- Corticosteroids
โน๏ธ Minor Interactions
- Antacids
- Ranitidine
- Vitamin K
- Herbal supplements (e.g., ginkgo, garlic)
๐ฝ๏ธ Food Interactions
Foods high in vitamin K (e.g., leafy greens) may reduce efficacy; consistent intake recommended., Cranberry juice may increase INR.
๐ท Alcohol Interaction
Acute alcohol intake may increase anticoagulant effect; chronic use may decrease effect.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to acenocoumarol, Active bleeding, Hemorrhagic tendencies, Severe liver or kidney disease, Uncontrolled hypertension, Pregnancy, Lactation, Recent surgery with bleeding risk, Bacterial endocarditis
๐ Monitoring Parameters
Prothrombin time (PT) and INR regularly; assess for signs of bleeding or thrombosis.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk in small amounts, but risk of bleeding in infant.
๐ Overdose Management
Administer vitamin K (phytonadione) orally or intravenously; severe bleeding may require fresh frozen plasma or prothrombin complex concentrate.
โฐ Missed Dose
Take as soon as remembered if within 12 hours; skip if >12 hours and resume next scheduled dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for acethromb 1mg tablet
View AllAlternative brands with exact same active ingredient (Acenocoumarol (1mg)):
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nicoz 1mg tabletAjanta Pharma Ltd โน26.92 13.7% CHEAPER
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nistrom 1mg tabletNeiss Labs Pvt Ltd โน27.50 11.9% CHEAPER
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cenorol 1mg tabletEast West Pharma โน29.16 6.5% CHEAPER
-
nicofax 1mg tabletChemo Healthcare Pvt Ltd โน53.44 71.3% COSTLIER
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aceno 1mg tabletZydus Cadila โน55.00 76.3% COSTLIER
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acenomac 1 tabletMacleods Pharmaceuticals Pvt Ltd โน59.40 90.4% COSTLIER
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altrom 1mg tabletIkon Remedies Pvt Ltd โน64.50 106.7% COSTLIER
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cgtrom 1mg tabletCmg Biotech Pvt Ltd โน66.00 111.5% COSTLIER
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nimalin 1mg tabletShinto Organics (P) Limited โน75.00 140.4% COSTLIER
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artiflo 1 tabletZuventus Healthcare Ltd โน99.50 218.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.