acestine 600 tablet

4.5 (15 reviews)

Acetylcysteine (600mg)

🏭 Johnlee Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is acestine 600 tablet used for?

Acyline Tablet (Acetylcysteine) is used to treat PAIN ANALGESICS. It contains Acetylcysteine (600mg), which Reduces mucus viscosity by breaking disulfide bonds; also acts as a precursor to. Always consult your doctor before use. Take as prescribed.

Generic Name: Acetylcysteine
Manufacturer: Johnlee Pharmaceuticals Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 acestine 600 tablet Uses & Benefits

Mucolytic in respiratory conditions (COPD, cystic fibrosis, bronchitis), acetaminophen overdose

Off-label uses: Prevention of contrast-induced nephropathy, treatment of pulmonary fibrosis

📋 Drug Information

Generic Name(s)	Acetylcysteine
Brand Name	Acyline Tablet
Manufacturer	Johnlee Pharmaceuticals Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	Acetylcysteine -Mucolytic
Route of Administration	Oral, intravenous (for overdose), inhalation
Storage	Store at room temperature (20-25°C), protect from moisture
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration

DistributionDistributes widely into body tissues and fluids

Protein Binding50-83%

MetabolismHepatic, primarily deacetylation to cysteine

Half-Life5.6 hours (adults), 11 hours (neonates)

ExcretionRenal (primarily as inactive metabolites)

Bioavailability6-10% (oral, due to extensive first-pass metabolism)

Onset of ActionRapid (within 1 hour for mucolytic effect)

Peak Plasma Time1-3 hours

Duration of Action4-6 hours

How It Works

Reduces mucus viscosity by breaking disulfide bonds; also acts as a precursor to glutathione, providing antioxidant effects

Mechanism Steps

1Acetylcysteine is deacetylated to cysteine in the liver

2Cysteine is a precursor for glutathione synthesis

3Glutathione conjugates with reactive metabolites of acetaminophen, preventing hepatotoxicity

💡 How to Take acestine 600 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of acestine 600 tablet

✅ Common Side Effects

Nausea
Vomiting
Rash
Fever
Drowsiness

🚨 Serious Side Effects

Anaphylactoid reaction
Bronchospasm
Stevens-Johnson syndrome
Seizures

⚠️ Rare Side Effects

Hepatotoxicity
Metabolic acidosis
Hypotension

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Nitroglycerin	Major	Increased hypotension and headache
Carbamazepine	Major	Decreased carbamazepine levels
Warfarin	Moderate	Increased INR and bleeding risk
Chloroquine	Moderate	Decreased chloroquine efficacy
Activated charcoal	Minor	Reduced acetylcysteine absorption
Tetracyclines	Minor	Decreased tetracycline absorption if taken simultaneously

🚨 Major Interactions

Nitroglycerin
Carbamazepine

⚡ Moderate Interactions

Warfarin
Chloroquine

ℹ️ Minor Interactions

Activated charcoal
Tetracyclines

🍽️ Food Interactions

None known

🍷 Alcohol Interaction

May increase risk of hepatotoxicity; avoid concurrent use

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to acetylcysteine, severe asthma (relative), peptic ulcer disease (relative)

📊 Monitoring Parameters

Liver function tests (in overdose), respiratory status, signs of hypersensitivity

🤱 Lactation Safety

Excreted in breast milk in small amounts; considered compatible with breastfeeding

💊 Overdose Management

Supportive care; monitor for anaphylactoid reactions, seizures, and metabolic acidosis

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose and resume regular schedule

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for acestine 600 tablet

View All

Alternative brands with exact same active ingredient (Acetylcysteine (600mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.