Acephin-LM Tablet SR - Uses, Price, Side Effects
What is acephin-lm tablet sr used for?
Acephin-LM Tablet SR is a combination medicine used to treat allergic symptoms such as sneezing, runny nose, and wheezing. It contains Montelukast, which blocks leukotrienes to reduce inflammation, and Levocetirizine, an antihistamine that relieves allergy symptoms. It is commonly prescribed for allergic rhinitis and asthma.
- Generic Name: Montelukast + Levocetirizine
- Manufacturer: Asvins Lifecare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acephin-lm tablet sr Uses & Benefits
Allergic rhinitis, asthma prophylaxis, urticaria
Off-label uses: Exercise-induced bronchoconstriction, Chronic idiopathic urticaria
๐ Drug Information
| Generic Name(s) | Montelukast + Levocetirizine |
| Brand Name | Acebrofact LM Tablet |
| Manufacturer | Asvins Lifecare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Leukotriene Receptor Antagonist + Antihistamine |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Montelukast blocks leukotriene D4 receptors; Levocetirizine blocks histamine H1 receptors
Mechanism Steps
๐ก How to Take acephin-lm tablet sr
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of acephin-lm tablet sr
โ Common Side Effects
- Headache
- Drowsiness
- Dry mouth
- Fatigue
- Pharyngitis
๐จ Serious Side Effects
- Anaphylaxis
- Angioedema
- Churg-Strauss syndrome
- Severe skin reactions
โ ๏ธ Rare Side Effects
- Hepatitis
- Thrombocytopenia
- Seizures
- Tinnitus
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Theophylline | Moderate | Increased risk of theophylline toxicity |
| Warfarin | Moderate | Increased risk of bleeding |
| Erythromycin | Minor | Decreased metabolism of montelukast |
๐จ Major Interactions
- Warfarin
- Phenytoin
- Rifampin
- CYP3A4 inducers
โก Moderate Interactions
- Aspirin
- NSAIDs
- Theophylline
- Erythromycin
โน๏ธ Minor Interactions
- Zafirlukast
- Gemfibrozil
๐ฝ๏ธ Food Interactions
No significant food interactions; avoid grapefruit juice (may increase montelukast levels)
๐ท Alcohol Interaction
Alcohol may increase CNS depression; avoid concurrent use
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to montelukast or levocetirizine; severe renal impairment (CrCl <10 mL/min)
๐ Monitoring Parameters
Liver function tests, renal function, asthma symptoms, allergic symptoms
๐คฑ Lactation Safety
Excreted in breast milk; use with caution
๐ Overdose Management
Symptomatic and supportive; no specific antidote
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double