ace plus 100mg tablet - Diclofenac (100mg) medicine

Ace Plus 100mg Tablet - Uses, Price, Side Effects

4.5 (11 reviews)
Diclofenac (100mg)
๐Ÿญ Gold Line ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is ace plus 100mg tablet used for?

Ace Plus 100mg Tablet contains Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation in conditions like arthritis, muscle aches, and dental pain. It works by blocking the production of prostaglandins, chemicals that cause pain and swelling.

  • Generic Name: Diclofenac
  • Manufacturer: Gold Line
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š ace plus 100mg tablet Uses & Benefits

Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, dysmenorrhea, musculoskeletal pain, postoperative pain, fever.

Off-label uses: Migraine, renal colic, pericarditis, patent ductus arteriosus closure in neonates.

๐Ÿ“‹ Drug Information

Generic Name(s)Diclofenac
Brand NameAdiflam 50mg Tablet
ManufacturerGold Line
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract.
DistributionWidely distributed throughout the body; crosses the placenta and enters breast milk.
Protein BindingMore than 99% bound to plasma proteins, primarily albumin.
MetabolismPrimarily hepatic via CYP2C9 and CYP3A4; undergoes first-pass metabolism.
Half-LifeApproximately 2 hours
ExcretionApproximately 65% renal and 35% biliary as metabolites.
BioavailabilityAbout 50% due to first-pass metabolism.
Onset of Action30 minutes to 1 hour
Peak Plasma Time1 to 2 hours
Duration of Action4 to 6 hours

How It Works

Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis.

Mechanism Steps

1Diclofenac inhibits cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2.
2COX-1 is constitutively expressed and produces prostaglandins involved in gastric protection, platelet aggregation, and renal function.
3COX-2 is induced by inflammation and produces prostaglandins that mediate pain, fever, and inflammation.

๐Ÿ’ก How to Take ace plus 100mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of ace plus 100mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Dyspepsia
  • Abdominal pain
  • Flatulence
  • Headache
  • Dizziness
  • Rash

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Perforation
  • Renal failure
  • Hepatic failure
  • Myocardial infarction
  • Stroke
  • Anaphylaxis
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Pancreatitis
  • Aseptic meningitis
  • Hematologic disorders (agranulocytosis, aplastic anemia)
  • Hepatitis
  • Nephrotic syndrome
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Aspirin Major Increased risk of gastrointestinal ulcers
Methotrexate Major Increased methotrexate toxicity
Lithium Moderate Increased lithium levels
ACE Inhibitors Moderate Reduced antihypertensive effect

๐Ÿšจ Major Interactions

  • Warfarin
  • Lithium
  • Methotrexate
  • Aspirin
  • Other NSAIDs
  • Anticoagulants
  • Corticosteroids

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Cyclosporine
  • Tacrolimus
  • Quinolone antibiotics

โ„น๏ธ Minor Interactions

  • Antacids
  • Cholestyramine
  • Digoxin
  • Phenytoin

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not significantly affect overall bioavailability.

๐Ÿท Alcohol Interaction

Increased risk of gastrointestinal bleeding and ulcers.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Moderate
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to diclofenac or any NSAID; history of asthma, urticaria, or allergic-type reactions after aspirin/NSAIDs; active peptic ulcer or GI bleeding; severe heart failure; severe renal or hepatic impairment; perioperative pain in CABG surgery.

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, blood pressure, signs of GI bleeding, CBC.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Symptomatic and supportive; no specific antidote; consider activated charcoal if recent ingestion.

โฐ Missed Dose

Take as soon as remembered unless almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for ace plus 100mg tablet

View All

Alternative brands with exact same active ingredient (Diclofenac (100mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

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