accunac 0.1% eye drop - Uses, Price, Side Effects & Substitutes
What is accunac 0.1% eye drop used for?
Amplinak Ophthalmic Suspension (Nepafenac) is used to treat OPHTHAL. It contains Nepafenac (0.1% w/v), which Nepafenac is a prodrug that is converted to amfenac, a nonsteroidal anti-inflamm. Always consult your doctor before use. Take as prescribed.
- Generic Name: Nepafenac
- Manufacturer: His Eyeness Ophthalmics Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ accunac 0.1% eye drop Uses & Benefits
Treatment of pain and inflammation associated with cataract surgery; reduction of macular edema.
Off-label uses: Treatment of diabetic macular edema, Prevention of cystoid macular edema
๐ Drug Information
| Generic Name(s) | Nepafenac |
| Brand Name | Amplinak Ophthalmic Suspension |
| Manufacturer | His Eyeness Ophthalmics Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (Topical) |
| Route of Administration | Ophthalmic (topical to the eye). |
| Storage | Store at 15ยฐC to 25ยฐC (59ยฐF to 77ยฐF); protect from light; keep bottle tightly closed. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Nepafenac is a prodrug that is converted to amfenac, a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis.
Mechanism Steps
๐ก How to Take accunac 0.1% eye drop
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of accunac 0.1% eye drop
โ Common Side Effects
- Eye pain
- Conjunctival hyperemia
- Blurred vision
- Foreign body sensation
- Headache
๐จ Serious Side Effects
- Corneal perforation
- Corneal thinning
- Increased intraocular pressure
- Delayed wound healing
โ ๏ธ Rare Side Effects
- Allergic reactions
- Stevens-Johnson syndrome
- Renal impairment (with systemic absorption)
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Other NSAIDs | Major | Additive gastrointestinal and renal toxicity |
| Anticoagulants | Major | Enhanced anticoagulant effect |
| Corticosteroids | Major | Increased risk of gastrointestinal ulceration |
| Aspirin | Moderate | Increased risk of bleeding |
| Clopidogrel | Moderate | Increased bleeding risk |
| SSRIs | Moderate | Increased bleeding risk |
| Diuretics | Moderate | Reduced diuretic efficacy |
| ACE inhibitors | Minor | Reduced antihypertensive effect |
| ARBs | Minor | Reduced antihypertensive effect |
| Beta-blockers | Minor | Reduced antihypertensive effect |
๐จ Major Interactions
- Warfarin
- Other NSAIDs
- Anticoagulants
- Corticosteroids
โก Moderate Interactions
- Aspirin
- Clopidogrel
- Selective serotonin reuptake inhibitors (SSRIs)
- Diuretics
โน๏ธ Minor Interactions
- ACE inhibitors
- Angiotensin receptor blockers (ARBs)
- Beta-blockers
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to nepafenac or any component; history of asthma, urticaria, or allergic-type reactions after aspirin or other NSAIDs.
๐ Monitoring Parameters
Monitor for signs of ocular irritation, bleeding, or infection; assess intraocular pressure if used with corticosteroids.
๐คฑ Lactation Safety
Not recommended; unknown if excreted in human milk.
๐ Overdose Management
Not expected with topical use; if ingested, symptomatic and supportive care.
โฐ Missed Dose
Apply the missed dose as soon as remembered; if near next dose, skip missed dose and resume regular schedule.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for accunac 0.1% eye drop
View AllAlternative brands with exact same active ingredient (Nepafenac (0.1% w/v)):
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nepaclub 0.1% eye dropOlamic Healthcare โน51.56 79.3% CHEAPER
-
nepanova 0.1% eye dropRenascent โน83.44 66.5% CHEAPER
-
choroid nepa eye dropIris Pharmaceuticals Pvt Ltd โน84.38 66.2% CHEAPER
-
ocunepa eye dropCalix Health Care โน93.75 62.4% CHEAPER
-
nepative eye dropQrative Care โน98.44 60.5% CHEAPER
-
i nac eye dropAppasamy Ocular Device Pvt Ltd โน102.09 59% CHEAPER
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Nepeye Opthalmic SuspensionEyekare Kilitch Limited โน103.00 58.7% CHEAPER
-
becanac 0.1% eye dropAcambis (india) Pharmaceuticals Private Limited โน103.13 58.6% CHEAPER
-
zetafenac eye dropBioquest Pharmaceuticals Pvt Ltd โน109.69 56% CHEAPER
-
nepagen eye dropRenova Life sciences Pvt Ltd โน110.00 55.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.