accuglim m 2mg/500mg tablet
What is accuglim m 2mg/500mg tablet used for?
Amaryl M 1mg Tablet PR (Glimepiride + Metformin) is used to treat ANTI DIABETIC. It contains Glimepiride (2mg) + Metformin (500mg), which Glimepiride: Stimulates insulin release from pancreatic beta cells; Metformin: D. Always consult your doctor before use. Take as prescribed.
- Generic Name: Glimepiride + Metformin
- Manufacturer: Cadell Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ accuglim m 2mg/500mg tablet Uses & Benefits
Type 2 diabetes mellitus when diet and exercise alone are inadequate
Off-label uses: Polycystic ovary syndrome (metformin component)
๐ Drug Information
| Generic Name(s) | Glimepiride + Metformin |
| Brand Name | Amaryl M 1mg Tablet PR |
| Manufacturer | Cadell Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Sulfonylurea + Biguanide |
| Route of Administration | Oral |
| Storage | Store at 25ยฐC (77ยฐF); excursions permitted to 15-30ยฐC (59-86ยฐF); protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Glimepiride: Stimulates insulin release from pancreatic beta cells; Metformin: Decreases hepatic glucose production, increases insulin sensitivity
Mechanism Steps
๐ก How to Take accuglim m 2mg/500mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of accuglim m 2mg/500mg tablet
โ Common Side Effects
- Hypoglycemia
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
๐จ Serious Side Effects
- Lactic acidosis
- Severe hypoglycemia
- Hepatic injury
- Pancreatitis
โ ๏ธ Rare Side Effects
- Megaloblastic anemia
- Photosensitivity
- Disulfiram-like reaction
- Cholestatic jaundice
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | Increased risk of hypoglycemia |
| Miconazole | Major | Enhanced hypoglycemic effect |
| Alcohol | Major | Increased risk of lactic acidosis and hypoglycemia |
| ACE inhibitors | Moderate | Enhanced hypoglycemic effect |
| Beta-blockers | Moderate | Mask hypoglycemia symptoms |
| Corticosteroids | Moderate | Hyperglycemia |
| Diuretics | Moderate | Hyperglycemia |
| NSAIDs | Moderate | Enhanced hypoglycemic effect |
| Cimetidine | Minor | Increased metformin levels |
| Nifedipine | Minor | Increased metformin absorption |
๐จ Major Interactions
- Insulin
- Other sulfonylureas
- Miconazole
- Phenylbutazone
- Alcohol
โก Moderate Interactions
- ACE inhibitors
- Beta-blockers
- Clarithromycin
- Corticosteroids
- Diuretics
- NSAIDs
โน๏ธ Minor Interactions
- Cimetidine
- Ranitidine
- Nifedipine
๐ฝ๏ธ Food Interactions
Food delays absorption of glimepiride; metformin absorption reduced by food
๐ท Alcohol Interaction
Increased risk of hypoglycemia and lactic acidosis
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Type 1 diabetes, diabetic ketoacidosis, severe renal impairment (eGFR <30), hepatic impairment, hypersensitivity, acute conditions with risk of hypoxia
๐ Monitoring Parameters
Blood glucose, HbA1c, renal function (serum creatinine, eGFR), hepatic function, signs of lactic acidosis
๐คฑ Lactation Safety
Contraindicated; glimepiride excreted in milk, metformin excreted in milk
๐ Overdose Management
Monitor blood glucose; treat hypoglycemia with oral glucose or IV dextrose; for metformin overdose, consider hemodialysis
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.
Found this to be a helpful product. Good results.