acarjohn m tablet - Uses, Price, Side Effects & Substitutes
What is acarjohn m tablet used for?
Acarjohn M Tablet (Acarbose + Metformin) is used to treat ANTI DIABETIC. It contains Acarbose (25mg) + Metformin (500mg), which Acarbose inhibits alpha-glucosidase, delaying carbohydrate digestion; Metformin . Always consult your doctor before use. Take as prescribed.
- Generic Name: Acarbose + Metformin
- Manufacturer: Johnlee Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acarjohn m tablet Uses & Benefits
Type 2 diabetes mellitus
Off-label uses: Polycystic ovary syndrome (Metformin), prediabetes
๐ Drug Information
| Generic Name(s) | Acarbose + Metformin |
| Brand Name | Acarjohn M Tablet |
| Manufacturer | Johnlee Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Alpha-glucosidase inhibitor + Biguanide |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Acarbose inhibits alpha-glucosidase, delaying carbohydrate digestion; Metformin decreases hepatic glucose production and increases insulin sensitivity
Mechanism Steps
๐ก How to Take acarjohn m tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of acarjohn m tablet
โ Common Side Effects
- Flatulence
- Diarrhea
- Abdominal pain
- Nausea
- Vomiting
๐จ Serious Side Effects
- Lactic acidosis
- Hypoglycemia
- Hepatotoxicity
- Pancreatitis
โ ๏ธ Rare Side Effects
- Pneumatosis cystoides intestinalis
- Subacute cutaneous lupus erythematosus
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | Increased hypoglycemia risk |
| Sulfonylureas | Major | Additive hypoglycemia |
| Alcohol | Major | Increased lactic acidosis risk |
| Cimetidine | Moderate | Reduced Metformin clearance |
| Furosemide | Moderate | Increased Metformin levels |
| Corticosteroids | Moderate | Hyperglycemic effect |
๐จ Major Interactions
- Insulin
- Sulfonylureas
- Meglitinides
- Alcohol
โก Moderate Interactions
- Cimetidine
- Furosemide
- Nifedipine
- Corticosteroids
โน๏ธ Minor Interactions
- Thiazide diuretics
- Oral contraceptives
- Phenytoin
๐ฝ๏ธ Food Interactions
Acarbose: taken with first bite of meal; Metformin: take with meals to reduce GI upset
๐ท Alcohol Interaction
Increased risk of lactic acidosis with Metformin; avoid excessive alcohol
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Renal impairment (CrCl <30), metabolic acidosis, diabetic ketoacidosis, hypersensitivity, hepatic impairment, GI obstruction
๐ Monitoring Parameters
Blood glucose, HbA1c, renal function, liver function, lactic acid levels
๐คฑ Lactation Safety
Acarbose: not excreted; Metformin: excreted in milk, caution
๐ Overdose Management
Supportive care; Metformin overdose may cause lactic acidosis, treat with hemodialysis
โฐ Missed Dose
Skip if missed; do not double dose