abzorb syndet bar - Clotrimazole (1% w/w) medicine

Abzorb Syndet Bar - Uses, Price, Side Effects

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๐Ÿญ Sun Pharmaceutical Industries Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is abzorb syndet bar used for?

Abzorb Syndet Bar is an antifungal soap containing Clotrimazole 1% w/w. It is used to treat and prevent fungal skin infections such as ringworm, jock itch, athlete's foot, and candidiasis. Clotrimazole works by inhibiting the growth of fungi, providing relief from itching, redness, and irritation.

  • Generic Name: Clotrimazole
  • Manufacturer: Sun Pharmaceutical Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š abzorb syndet bar Uses & Benefits

Treatment of fungal skin infections such as athlete's foot, ringworm, jock itch, and candidal diaper rash.

Off-label uses: Pityriasis versicolor, Seborrheic dermatitis

๐Ÿ“‹ Drug Information

Generic Name(s)Clotrimazole
Brand NameAf -c dusting powder
ManufacturerSun Pharmaceutical Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationTopical (dusting powder).
StorageStore at room temperature (20-25ยฐC); keep container tightly closed.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after topical application; absorption through intact skin is less than 0.5%.
DistributionNot well characterized; primarily remains in the stratum corneum after topical application.
Protein BindingNot applicable for topical use; systemic protein binding is approximately 90% if absorbed.
MetabolismHepatic metabolism via CYP450 enzymes to inactive metabolites.
Half-LifeNot applicable for topical use; systemic half-life is approximately 3-6 hours.
ExcretionPrimarily via feces (biliary excretion) and urine as metabolites.
BioavailabilityNegligible systemic bioavailability after topical application.
Onset of ActionWithin 24-48 hours of application.
Peak Plasma TimeNot applicable for topical use.
Duration of ActionUp to 24 hours after single application.

How It Works

Inhibits fungal cytochrome P450 14ฮฑ-demethylase, disrupting ergosterol synthesis and fungal cell membrane integrity.

Mechanism Steps

1Clotrimazole binds to fungal CYP51 (lanosterol 14ฮฑ-demethylase).
2Inhibits the conversion of lanosterol to ergosterol.
3Depletes ergosterol in fungal cell membrane.

๐Ÿ’ก How to Take abzorb syndet bar

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of abzorb syndet bar

โœ… Common Side Effects

  • Skin irritation
  • Burning
  • Stinging
  • Redness

๐Ÿšจ Serious Side Effects

  • Allergic contact dermatitis
  • Angioedema (rare)

โš ๏ธ Rare Side Effects

  • Urticaria
  • Blistering
  • Exfoliation

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Moderate Increased anticoagulant effect
Cyclosporine Moderate Increased cyclosporine levels
Tacrolimus Moderate Increased tacrolimus levels

๐Ÿšจ Major Interactions

  • Warfarin
  • CYP3A4 substrates

โšก Moderate Interactions

  • Oral hypoglycemics
  • Phenytoin

โ„น๏ธ Minor Interactions

  • Antacids
  • H2 antagonists

๐Ÿฝ๏ธ Food Interactions

No significant food interactions for topical use.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to clotrimazole or any component.

๐Ÿ“Š Monitoring Parameters

Clinical improvement of skin lesions; signs of irritation or allergic reaction.

๐Ÿคฑ Lactation Safety

Likely safe; minimal systemic absorption. Avoid application to breast area.

๐Ÿ’Š Overdose Management

Unlikely with topical use; if ingested, symptomatic and supportive care.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for abzorb syndet bar

View All

Alternative brands with exact same active ingredient (Clotrimazole (1% w/w)):

Medical Note: Always consult your doctor before switching medications.

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