Abmef-DS 500mg/325mg Tablet - Uses, Price, Side Effects
What is abmef-ds 500mg/325mg tablet used for?
Abmef-DS 500mg/325mg Tablet is a combination of Mefenamic Acid (500mg) and Paracetamol (325mg) used to relieve pain and reduce fever. Mefenamic Acid is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of prostaglandins, while Paracetamol acts on the brain to reduce fever and pain. It is commonly used for headaches, dental pain, menstrual cramps, and musculoskeletal pain.
- Generic Name: Mefenamic Acid + Paracetamol
- Manufacturer: Aamorb Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ abmef-ds 500mg/325mg tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Mefenamic Acid + Paracetamol |
| Brand Name | Abmef-DS Oral Suspension |
| Manufacturer | Aamorb Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Nonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Mefenamic acid inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis; Paracetamol inhibits COX in the central nervous system and modulates pain perception.
Mechanism Steps
๐ก How to Take abmef-ds 500mg/325mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of abmef-ds 500mg/325mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Dyspepsia
- Diarrhea
- Dizziness
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Hepatotoxicity
- Renal failure
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Thrombocytopenia
- Pancreatitis
- Aplastic anemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Aspirin | Moderate | Increased risk of gastrointestinal bleeding |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Lithium
- Aspirin
- Alcohol
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- SSRIs
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of hepatotoxicity (paracetamol) and GI bleeding (mefenamic acid).
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy.
๐ Monitoring Parameters
Liver function, renal function, CBC, signs of GI bleeding.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for mefenamic acid.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
Found this to be a helpful product. Good results.