abiflu 150 tablet - Fluconazole (150mg) medicine

Abiflu 150 Tablet - Uses, Price, Side Effects

4.8 (16 reviews)

Fluconazole (150mg)

🏭 Abigail Care Pharmaceutical 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is abiflu 150 tablet used for?

Abiflu 150 Tablet contains Fluconazole 150mg, an antifungal medication used to treat vaginal candidiasis (yeast infection), oral thrush, and other systemic fungal infections. It works by inhibiting the growth of fungi by interfering with their cell membrane synthesis. Take one tablet as a single dose for vaginal candidiasis, or as directed by your doctor for other infections.

Generic Name: Fluconazole
Manufacturer: Abigail Care Pharmaceutical
Form: Allopathy
Pregnancy Category: D
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 abiflu 150 tablet Uses & Benefits

Vaginal candidiasis, oropharyngeal candidiasis, esophageal candidiasis, systemic candidiasis, cryptococcal meningitis, prophylaxis in immunocompromised patients

Off-label uses: Coccidioidomycosis, histoplasmosis, blastomycosis, dermatophytosis, onychomycosis

📋 Drug Information

Generic Name(s)	Fluconazole
Brand Name	AF 150 Tablet DT
Manufacturer	Abigail Care Pharmaceutical
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Fungal ergosterol synthesis inhibitor
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from light and moisture
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; bioavailability >90%

DistributionWidely distributed into body tissues and fluids, including CSF

Protein Binding11-12%

MetabolismHepatic metabolism via CYP2C9 and CYP3A4

Half-Life30 hours (range 20-50 hours)

ExcretionPrimarily renal (80% unchanged)

Bioavailability>90%

Onset of ActionRapid; therapeutic levels achieved within 1-2 hours

Peak Plasma Time1-2 hours

Duration of Action24 hours

How It Works

Inhibits fungal cytochrome P450 14α-demethylase, preventing conversion of lanosterol to ergosterol, disrupting fungal cell membrane synthesis

Mechanism Steps

1Fluconazole enters fungal cell via diffusion

2Binds to fungal cytochrome P450 14α-demethylase (CYP51)

3Inhibits demethylation of lanosterol to ergosterol

💡 How to Take abiflu 150 tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⚠️ Side Effects of abiflu 150 tablet

✅ Common Side Effects

Headache
Nausea
Abdominal pain
Diarrhea
Dizziness
Rash

🚨 Serious Side Effects

Hepatotoxicity
QT prolongation
Torsades de pointes
Stevens-Johnson syndrome
Anaphylaxis
Exfoliative dermatitis

⚠️ Rare Side Effects

Alopecia
Seizures
Thrombocytopenia
Leukopenia
Agranulocytosis
Hypertriglyceridemia
Hypokalemia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Cisapride	Major	Risk of cardiac arrhythmias
Sulfonylureas	Moderate	Increased hypoglycemic effect

🚨 Major Interactions

Warfarin
Phenytoin
Sulfonylureas
Cisapride
Terfenadine
Astemizole
Rifampin
Rifabutin
Tacrolimus
Sirolimus
Alfentanil
Benzodiazepines (midazolam, triazolam)
Calcium channel blockers (nifedipine, verapamil)
HMG-CoA reductase inhibitors (atorvastatin, simvastatin)
Losartan
Methadone
NSAIDs (celecoxib, flurbiprofen, naproxen, ibuprofen)
Oral contraceptives
Pimozide
Quinidine
Tolbutamide
Warfarin
Zidovudine

⚡ Moderate Interactions

Cyclosporine
Theophylline
Hydrochlorothiazide
Phenytoin
Rifampin
Rifabutin
Tacrolimus
Sirolimus
Alfentanil
Benzodiazepines (midazolam, triazolam)
Calcium channel blockers (nifedipine, verapamil)
HMG-CoA reductase inhibitors (atorvastatin, simvastatin)
Losartan
Methadone
NSAIDs (celecoxib, flurbiprofen, naproxen, ibuprofen)
Oral contraceptives
Pimozide
Quinidine
Tolbutamide
Warfarin
Zidovudine

ℹ️ Minor Interactions

Cimetidine
Antacids
Sucralfate
Didanosine
Ritonavir
Saquinavir
Zidovudine

🍽️ Food Interactions

No significant food interactions; absorption not affected by food

🍷 Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Low

Heart

Low

Pregnancy

Category D

🚫 Contraindications

Hypersensitivity to fluconazole or azoles; concomitant use with terfenadine, astemizole, cisapride, pimozide, quinidine

📊 Monitoring Parameters

Liver function tests, renal function, signs of hepatotoxicity, QT interval if risk factors

🤱 Lactation Safety

Excreted in breast milk; use with caution

💊 Overdose Management

Symptomatic and supportive; hemodialysis may enhance elimination

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for abiflu 150 tablet

View All

Alternative brands with exact same active ingredient (Fluconazole (150mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.