Abalam Tablet - Uses, Price, Side Effects, and Dosage
What is abalam tablet used for?
Abalam Tablet is a combination of Abacavir (600mg) and Lamivudine (300mg), used to treat HIV infection. It works by reducing the amount of HIV in the body and improving immune function. It is taken twice daily with or without food. Common side effects include nausea, headache, and fatigue.
- Generic Name: Abacavir + Lamivudine
- Manufacturer: Genix Lifescience Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ abalam tablet Uses & Benefits
HIV-1 infection in combination with other antiretroviral agents.
Off-label uses: HIV post-exposure prophylaxis (PEP) in combination with other agents.
๐ Drug Information
| Generic Name(s) | Abacavir + Lamivudine |
| Brand Name | Abamune L |
| Manufacturer | Genix Lifescience Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Nucleoside Reverse Transcriptase Inhibitors (NRTIs) |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Abacavir and lamivudine are nucleoside analogs that inhibit HIV reverse transcriptase by competing with natural substrates and causing chain termination.
Mechanism Steps
๐ก How to Take abalam tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of abalam tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Headache
- Fatigue
- Insomnia
- Rash
๐จ Serious Side Effects
- Hypersensitivity reaction (fever, rash, GI symptoms, respiratory symptoms)
- Lactic acidosis
- Severe hepatomegaly with steatosis
- Pancreatitis
- Immune reconstitution syndrome
โ ๏ธ Rare Side Effects
- Myocardial infarction
- Stevens-Johnson syndrome
- Peripheral neuropathy
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Moderate | Increased liver toxicity |
| Methadone | Moderate | Reduced methadone levels |
| Ribavirin | Moderate | Increased risk of anemia |
๐จ Major Interactions
- Methadone
- Ribavirin
- Interferon alfa
- Orlistat
โก Moderate Interactions
- Trimethoprim/sulfamethoxazole
- Valganciclovir
- Ganciclovir
- Mycophenolate
โน๏ธ Minor Interactions
- Ethanol
- Acetaminophen
- Oral contraceptives
๐ฝ๏ธ Food Interactions
May be taken with or without food; high-fat meal may slightly delay absorption but not clinically significant.
๐ท Alcohol Interaction
Alcohol may increase abacavir levels; avoid excessive alcohol consumption.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to abacavir (especially HLA-B*5701 positive), severe hepatic impairment, end-stage renal disease (CrCl <30 mL/min).
๐ Monitoring Parameters
HIV viral load, CD4 count, hypersensitivity symptoms (fever, rash), hepatic function, renal function, lactic acidosis symptoms.
๐คฑ Lactation Safety
Not recommended; HIV-infected mothers should not breastfeed to avoid transmission.
๐ Overdose Management
Supportive care; hemodialysis may remove lamivudine but not abacavir.
โฐ Missed Dose
If missed within 12 hours, take as soon as possible; if >12 hours, skip and resume next dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.