aacef 1000mg injection - Uses, Price, Side Effects & Substitutes
What is aacef 1000mg injection used for?
Accuzon 1g Injection (Ceftriaxone) is used to treat ANTI INFECTIVES. It contains Ceftriaxone (1000mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ceftriaxone
- Manufacturer: Alpic Biotech Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ aacef 1000mg injection Uses & Benefits
Lower respiratory tract infections, skin and soft tissue infections, urinary tract infections, pelvic inflammatory disease, bacterial septicemia, bone and joint infections, intra-abdominal infections, meningitis, surgical prophylaxis
Off-label uses: Lyme disease, Syphilis, Gonococcal infections
๐ Drug Information
| Generic Name(s) | Ceftriaxone |
| Brand Name | Accuzon 1g Injection |
| Manufacturer | Alpic Biotech Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Intramuscular or intravenous |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light; reconstituted solution stable for 24 hours at room temperature or 3 days refrigerated |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase activity, and activating autolytic enzymes
Mechanism Steps
๐ก How to Take aacef 1000mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of aacef 1000mg injection
โ Common Side Effects
- Diarrhea
- Injection site reactions (pain, induration)
- Rash
- Eosinophilia
- Thrombocytosis
๐จ Serious Side Effects
- Severe allergic reactions (anaphylaxis)
- Stevens-Johnson syndrome
- Clostridioides difficile-associated diarrhea
- Hemolytic anemia
- Seizures
โ ๏ธ Rare Side Effects
- Pseudomembranous colitis
- Biliary sludge or pseudolithiasis
- Agranulocytosis
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Alcohol | Major | Disulfiram-like reaction |
| Calcium-containing solutions | Major | Precipitation risk, especially in neonates |
| Aminoglycosides | Moderate | Increased nephrotoxicity risk |
| Loop diuretics | Moderate | Increased nephrotoxicity risk |
| Probenecid | Moderate | Decreased ceftriaxone excretion |
| Oral contraceptives | Minor | Reduced contraceptive efficacy |
| BCG vaccine | Minor | Reduced vaccine efficacy |
| Typhoid vaccine | Minor | Reduced vaccine efficacy |
๐จ Major Interactions
- Warfarin
- Alcohol
- Calcium-containing solutions
โก Moderate Interactions
- Aminoglycosides
- Loop diuretics
- Probenecid
โน๏ธ Minor Interactions
- Oral contraceptives
- BCG vaccine
- Typhoid vaccine
๐ฝ๏ธ Food Interactions
None known
๐ท Alcohol Interaction
Disulfiram-like reaction (flushing, headache, nausea, vomiting) possible
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to ceftriaxone or any cephalosporin; hyperbilirubinemic neonates (especially premature); concomitant use with calcium-containing IV solutions in neonates
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of superinfection, bleeding tendencies
๐คฑ Lactation Safety
Excreted in breast milk in low concentrations; generally considered compatible with breastfeeding
๐ Overdose Management
Supportive care; hemodialysis may reduce serum levels
โฐ Missed Dose
Administer as soon as remembered; if near next dose, skip missed dose and resume regular schedule
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for aacef 1000mg injection
View AllAlternative brands with exact same active ingredient (Ceftriaxone (1000mg)):
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wyceft 1000mg injectionVostok & Wilcure Remedies โน8.90 90.7% CHEAPER
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cefaxon 1000mg injectionRuan Life Sciences Pvt Ltd โน13.00 86.5% CHEAPER
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ceftrisone 1000mg injectionShreya Life Sciences Pvt Ltd โน21.25 77.9% CHEAPER
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eldocef 1000mg injectionElder Pharmaceuticals Ltd โน23.75 75.3% CHEAPER
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kocef 1000mg injectionKopran Ltd โน25.00 74% CHEAPER
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ivitax 1000mg injectionVhb Life Sciences Inc โน25.50 73.4% CHEAPER
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controx 1000mg injectionConcept Pharmaceuticals Ltd โน28.75 70.1% CHEAPER
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xone hospital 1000mg injectionAlkem Laboratories Ltd โน28.75 70.1% CHEAPER
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cafzone 1000mg injectionInd Swift Laboratories Ltd โน29.30 69.5% CHEAPER
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axone 1000mg injectionCadila Pharmaceuticals Ltd โน30.00 68.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.