a2b h 40 mg/12.5 mg tablet - Uses, Price, Side Effects & Substitutes
What is a2b h 40 mg/12.5 mg tablet used for?
Arbitel-H Tablet (Telmisartan + Hydrochlorothiazide) is used to treat CARDIAC. It contains Telmisartan (40mg) + Hydrochlorothiazide (12.5mg), which Telmisartan blocks angiotensin II AT1 receptors; Hydrochlorothiazide inhibits so. Always consult your doctor before use. Take as prescribed.
- Generic Name: Telmisartan + Hydrochlorothiazide
- Manufacturer: Fidelity Lifesciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ a2b h 40 mg/12.5 mg tablet Uses & Benefits
Hypertension (first-line or add-on therapy)
Off-label uses: Heart failure, diabetic nephropathy (limited evidence)
๐ Drug Information
| Generic Name(s) | Telmisartan + Hydrochlorothiazide |
| Brand Name | Arbitel-H Tablet |
| Manufacturer | Fidelity Lifesciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Angiotensin II Receptor Blocker + Thiazide Diuretic |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Telmisartan blocks angiotensin II AT1 receptors; Hydrochlorothiazide inhibits sodium reabsorption in distal tubules
Mechanism Steps
๐ก How to Take a2b h 40 mg/12.5 mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of a2b h 40 mg/12.5 mg tablet
โ Common Side Effects
- Dizziness
- Headache
- Fatigue
- Hypokalemia
- Hyperuricemia
- Increased creatinine
๐จ Serious Side Effects
- Angioedema
- Acute renal failure
- Severe hypotension
- Hyperkalemia
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Pancreatitis
- Hepatic dysfunction
- Photosensitivity
- Blood dyscrasias
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Lithium | Major | Increased lithium toxicity risk |
| ACE inhibitors | Major | Increased risk of hypotension and renal impairment |
| Aliskiren | Major | Increased risk of hyperkalemia and hypotension |
| NSAIDs | Major | Reduced antihypertensive effect and increased renal risk |
| Potassium-sparing diuretics | Major | Hyperkalemia risk |
| Digoxin | Moderate | Hypokalemia may increase digoxin toxicity |
| Warfarin | Moderate | No significant interaction, but monitor INR |
| Antidiabetic agents | Moderate | Hydrochlorothiazide may increase blood glucose |
| Corticosteroids | Moderate | Increased hypokalemia risk |
| Cholestyramine | Minor | Reduced absorption of hydrochlorothiazide |
| Colestipol | Minor | Reduced absorption of hydrochlorothiazide |
| Barbiturates | Minor | Increased orthostatic hypotension risk |
๐จ Major Interactions
- Lithium
- ACE inhibitors
- Aliskiren
- NSAIDs
- Potassium-sparing diuretics
โก Moderate Interactions
- Digoxin
- Warfarin
- Antidiabetic agents
- Corticosteroids
โน๏ธ Minor Interactions
- Cholestyramine
- Colestipol
- Barbiturates
๐ฝ๏ธ Food Interactions
Avoid potassium-rich foods; take with or without food
๐ท Alcohol Interaction
May potentiate orthostatic hypotension
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Anuria, hypersensitivity, pregnancy (2nd/3rd trimester), severe hepatic impairment, refractory hypokalemia
๐ Monitoring Parameters
Blood pressure, serum electrolytes (K+, Na+), renal function, blood glucose, uric acid
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; monitor electrolytes, renal function; consider gastric lavage
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose