a1a 10mg/75mg capsule - Uses, Price, Side Effects & Substitutes
What is a1a 10mg/75mg capsule used for?
Aztor Asp 75 Capsule (Atorvastatin + Aspirin) is used to treat CARDIAC. It contains Atorvastatin (10mg) + Aspirin (75mg), which Atorvastatin: Inhibits HMG-CoA reductase, reducing cholesterol synthesis; Aspiri. Always consult your doctor before use. Take as prescribed.
- Generic Name: Atorvastatin + Aspirin
- Manufacturer: Strides shasun Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ a1a 10mg/75mg capsule Uses & Benefits
Primary and secondary prevention of cardiovascular events in patients with hyperlipidemia and at risk of thrombotic events.
Off-label uses: Not applicable.
๐ Drug Information
| Generic Name(s) | Atorvastatin + Aspirin |
| Brand Name | Aztor Asp 75 Capsule |
| Manufacturer | Strides shasun Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG-CoA Reductase Inhibitor + Antiplatelet Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Atorvastatin: Inhibits HMG-CoA reductase, reducing cholesterol synthesis; Aspirin: Irreversibly inhibits cyclooxygenase (COX-1), reducing thromboxane A2 production and platelet aggregation.
Mechanism Steps
๐ก How to Take a1a 10mg/75mg capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of a1a 10mg/75mg capsule
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Diarrhea
- Muscle pain
- Dyspepsia
- Increased liver enzymes
๐จ Serious Side Effects
- Rhabdomyolysis
- Hepatotoxicity
- Gastrointestinal bleeding
- Hemorrhagic stroke
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Myopathy
- Pancreatitis
- Thrombocytopenia
- Interstitial lung disease
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Ciclosporin | Major | Increased atorvastatin levels and risk of myopathy |
| Clarithromycin | Major | Increased atorvastatin levels and risk of myopathy |
| Itraconazole | Major | Increased atorvastatin levels and risk of myopathy |
| HIV protease inhibitors | Major | Increased atorvastatin levels and risk of myopathy |
| Methotrexate | Major | Increased methotrexate toxicity |
| Digoxin | Moderate | Increased digoxin levels |
| Oral contraceptives | Moderate | Increased contraceptive levels |
| Colchicine | Moderate | Increased risk of myopathy |
| Antacids | Moderate | Reduced atorvastatin absorption |
| Fibrates | Moderate | Increased risk of myopathy |
| Niacin | Moderate | Increased risk of myopathy |
| Grapefruit juice | Minor | Increased atorvastatin levels |
| Vitamin K antagonists (low dose) | Minor | Minor INR changes |
| Spironolactone | Minor | Reduced diuretic effect |
๐จ Major Interactions
- Warfarin
- Ciclosporin
- Clarithromycin
- Itraconazole
- HIV protease inhibitors
- Methotrexate
โก Moderate Interactions
- Digoxin
- Oral contraceptives
- Colchicine
- Antacids
- Fibrates
- Niacin
โน๏ธ Minor Interactions
- Grapefruit juice
- Vitamin K antagonists (low dose)
- Spironolactone
๐ฝ๏ธ Food Interactions
Grapefruit juice increases atorvastatin levels; avoid high-fat meals with aspirin.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding with aspirin; alcohol may affect atorvastatin metabolism.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active liver disease, unexplained persistent liver enzyme elevations, pregnancy, breastfeeding, active peptic ulcer, bleeding disorders, hypersensitivity to any component.
๐ Monitoring Parameters
Liver function tests, lipid profile, renal function, signs of bleeding, INR if on warfarin.
๐คฑ Lactation Safety
Atorvastatin: Not recommended; Aspirin: Excreted in breast milk, avoid high doses.
๐ Overdose Management
Symptomatic and supportive care; for aspirin overdose, consider gastric lavage, activated charcoal, and hemodialysis in severe cases.
โฐ Missed Dose
Take as soon as remembered unless close to next dose; do not double dose.