zyquin 400mg infusion - Gatifloxacin (400mg) medicine

Algat Eye Drop: Complete Guide to Uses, Side Effects, and Safety

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🏭 Zydus Cadila 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for bacterial eye infections.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe eye pain or swelling
  • Sudden vision loss or severe blurred vision
  • Swelling of the face, lips, or throat
  • Difficulty breathing or swallowing
  • New or worsening eye redness, discharge, or pain
  • Signs of an allergic reaction such as rash, itching, or hives

If experiencing severe symptoms, call emergency services immediately.

What is zyquin 400mg infusion used for?

This medicine is an antibiotic eye drop used to treat bacterial eye infections such as conjunctivitis and keratitis. It works by killing bacteria that cause the infection. Use it exactly as prescribed by your eye doctor.

  • Generic Name: Gatifloxacin (400mg)
  • Manufacturer: Zydus Cadila
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 zyquin 400mg infusion के बारे में (Hindi Summary)

उपयोग: यह दवा गैटीफ्लोक्सासिन नामक एंटीबायोटिक की आई ड्रॉप है, जिसका उपयोग बैक्टीरियल आंखों के संक्रमण जैसे कंजंक्टिवाइटिस (आंख आना) और कॉर्नियल अल्सर के इलाज के लिए किया जाता है। यह आंखों में होने वाले बैक्टीरिया को मारकर संक्रमण को ठीक करती है। इसे डॉक्टर के बताए अनुसार ही उपयोग करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में आंखों में जलन, लालिमा, धुंधला दिखना, और मुंह में कड़वा स्वाद शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ मिनटों में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको आंखों में तेज दर्द, सूजन, या एलर्जी के लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग केवल आंखों में करें। उपयोग से पहले और बाद में हाथ धोएं। ड्रॉपर की नोक को आंख या किसी सतह से न छुएं। यदि आप कॉन्टैक्ट लेंस पहनते हैं, तो दवा डालने से पहले उन्हें निकाल दें और 15 मिनट बाद ही वापस पहनें। दवा को बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 zyquin 400mg infusion Uses & Benefits

[{"condition":"Bacterial conjunctivitis","description":"Treats bacterial infection of the conjunctiva, the clear membrane covering the white part of the eye and inner eyelids, reducing redness, discharge, and irritation.","evidence":"Well-established"},{"condition":"Bacterial keratitis","description":"Used to treat bacterial infection of the cornea, which can cause pain, blurred vision, and sensitivity to light.","evidence":"Well-established"},{"condition":"Corneal ulcers","description":"Helps heal bacterial corneal ulcers by killing the bacteria that cause the infection.","evidence":"Well-established"},{"condition":"Perioperative prophylaxis","description":"Used before and after certain eye surgeries to prevent bacterial infection.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Trachoma","description":"Sometimes used off-label for trachoma, a bacterial eye infection caused by Chlamydia trachomatis, but other antibiotics are usually preferred.","evidence":"Limited"}]

Primary treatment for: Bacterial conjunctivitis

Also treats: Bacterial keratitis, Corneal ulcers

📋 Drug Information

Generic Name(s)Gatifloxacin (400mg)
Brand Namezyquin 400mg infusion
ManufacturerZydus Cadila
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassQuinolones/ Fluroquinolones
Route of AdministrationOphthalmic
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and excessive heat. Do not freeze. Keep the bottle tightly closed when not in use.
Shelf Life24 months from the date of manufacture. Discard 30 days after opening the bottle.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always wash your hands before and after applying this medicine to prevent contamination.
2
Do not touch the dropper tip to your eye or any surface, as this can introduce new bacteria.
3
If you wear contact lenses, remove them before using this medicine and wait at least 15 minutes before reinserting them.
4
Complete the full course of treatment even if your symptoms improve, to prevent the infection from returning.
5
If your symptoms do not improve within 7 days, contact your eye doctor for further evaluation.
6
Do not share your eye drops with anyone else, as this can spread infection.
7
Store the bottle tightly closed and away from direct sunlight.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Redness and discharge from the eye
This medicine is commonly prescribed for bacterial conjunctivitis.
Likely Use
Eye pain and blurred vision
This medicine may be used for bacterial keratitis or corneal ulcers.
Likely Use
Itchy, watery eyes without discharge
This medicine is not for allergic conjunctivitis.
Not Primary
Dry eyes
This medicine is not a lubricant and should not be used for dry eyes.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAfter topical application to the eye, gatifloxacin is absorbed into the aqueous humor and corneal tissues. Systemic absorption is minimal but can occur, especially if the eye is inflamed or if the drops are swallowed through the nasolacrimal duct.
DistributionGatifloxacin distributes well into eye tissues, including the cornea, aqueous humor, and conjunctiva. It also distributes into tears. Systemic distribution is limited after topical eye use.
Protein BindingApproximately 20% of gatifloxacin is bound to plasma proteins.
MetabolismGatifloxacin undergoes limited metabolism in the liver. Most of the drug is excreted unchanged.
Half-LifeThe elimination half-life of gatifloxacin is approximately 7 to 8 hours after systemic administration. After topical eye use, the half-life in eye tissues may differ.
ExcretionGatifloxacin is primarily excreted unchanged in the urine. A small amount is excreted in the feces.
BioavailabilitySystemic bioavailability after topical eye administration is low, but it can be increased if the eye is inflamed or if the drops are swallowed.
Onset of ActionImprovement in symptoms may begin within 1 to 2 days of starting treatment, but complete healing may take several days.
Peak Plasma TimePeak plasma concentrations after topical eye use are very low and are usually reached within 1 to 2 hours.
Duration of ActionThe antibacterial effect lasts for several hours after each dose. The recommended dosing schedule maintains effective concentrations in the eye.

How It Works

This medicine works by inhibiting two enzymes in bacteria: DNA gyrase and topoisomerase IV. These enzymes are essential for bacterial DNA replication, transcription, repair, and recombination. By blocking them, this medicine stops bacteria from multiplying and causes them to die. This action is specific to bacterial cells and does not affect human cells.

Mechanism Steps

1
Entry into bacterial cell: This medicine penetrates the bacterial cell wall and enters the cytoplasm.
2
Binding to DNA gyrase: It binds to the DNA gyrase enzyme and blocks its ability to supercoil DNA, which is necessary for replication.
3
Binding to topoisomerase IV: It also binds to topoisomerase IV, preventing the separation of replicated DNA strands.
4
Inhibition of DNA replication: With both enzymes blocked, the bacterial DNA cannot be copied or repaired.
5
Bacterial cell death: The bacteria cannot multiply and eventually die, clearing the infection.

💡 How to Take zyquin 400mg infusion

Strength: Ophthalmic solution containing gatifloxacin 0.3% w/v (3 mg/mL).

1Wash your hands thoroughly with soap and water.
2Shake the bottle gently before use.
3Tilt your head back and pull down your lower eyelid to form a small pocket.
4Hold the dropper above your eye and squeeze one drop into the pocket. Do not touch the dropper to your eye.
5Close your eye gently for 1 to 2 minutes. Do not blink or rub your eye.
6Press your finger gently on the inner corner of your eye for 1 minute to prevent the medicine from draining into your throat.
7Wipe away any excess liquid with a clean tissue.
8Replace the cap on the bottle and wash your hands again.

Dosage Information

Adult DosageThe usual adult dose for bacterial conjunctivitis is 1 drop in the affected eye every 2 hours while awake, up to 8 times a day, for the first 2 days, then 1 drop 4 times a day for the next 5 days. For corneal ulcers, the dose is 1 drop every 30 minutes to 2 hours while awake, then 1 drop 4 to 6 times a day. The dose must be individualized by a qualified clinician based on the indication, severity of infection, and patient response.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are required for elderly patients. However, elderly patients may be more susceptible to side effects and should be monitored closely.
Renal ImpairmentNo dosage adjustment is required for topical ophthalmic use in patients with renal impairment, as systemic absorption is minimal.
Hepatic ImpairmentNo dosage adjustment is required for topical ophthalmic use in patients with hepatic impairment, as systemic absorption is minimal.
Maximum Daily DoseThe maximum daily dose for ophthalmic use depends on the indication and is determined by the prescribing doctor. Do not exceed the prescribed frequency.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of zyquin 400mg infusion

✅ Common Side Effects

Eye irritation or burning (Common (5-10%))
This usually goes away within a few minutes. If it persists or is severe, contact your doctor.
Blurred vision (Common (5-10%))
Wait until your vision clears before driving or operating machinery. If blurring continues, consult your doctor.
Bad taste in mouth (Common (5-10%))
This happens when drops drain into the throat. It is harmless and goes away on its own.
Eye redness or discharge (Common (5-10%))
This may be part of the infection or a mild reaction. If it worsens, contact your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you have swelling of the face, lips, throat, difficulty breathing, or a severe rash.
Severe eye pain or swelling (Rare (<0.1%))
Stop using the medicine and contact your eye doctor immediately.
New eye infection (superinfection) (Rare (<0.1%))
If you notice new or worsening symptoms such as increased redness, pain, or discharge, consult your doctor.

⚠️ Rare Side Effects

Corneal deposits
Report any changes in vision to your doctor.
Uveitis
Seek medical attention if you have eye pain, redness, or sensitivity to light.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to gatifloxacin or other fluoroquinolone antibiotics","Viral or fungal eye infections","Use in children under 1 year of age (safety not established)"]

⚠️ Warnings & Precautions

["Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi. If superinfection occurs, discontinue use and consult a doctor.","Do not touch the dropper tip to any surface to avoid contamination.","If you experience an allergic reaction, stop using this medicine and seek medical help.","Contact lenses should not be worn during treatment of eye infections.","This medicine is for ophthalmic use only. Do not swallow.","If symptoms do not improve within 7 days, consult your doctor."]

🤱 Lactation Safety

It is not known whether gatifloxacin is excreted in human breast milk after topical eye use. Systemically administered gatifloxacin is excreted in breast milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is used by a nursing woman. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to its topical nature. If accidental ingestion occurs, drink plenty of water and contact a poison control center or doctor immediately. If excessive drops are applied to the eye, rinse with warm water.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Use this medicine only in the eye, as directed by your doctor. Wash your hands before and after using the drops. Do not touch the dropper tip to your eye, eyelid, or any surface, because this can contaminate the bottle. If you wear contact lenses, remove them before using this medicine and wait at least 15 minutes before putting them back in, unless your doctor tells you otherwise. Do not use this medicine for longer than prescribed, because prolonged use can lead to a secondary fungal or resistant bacterial infection. If your symptoms do not improve within a few days or if they get worse, contact your eye doctor. Keep this medicine out of reach of children. Do not use this medicine after the expiry date printed on the bottle.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to the side effects of this medicine. They should use it with caution and report any unusual symptoms to their doctor.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Gatifloxacin is classified as Pregnancy Category C, and its safety during pregnancy has not been fully established.

🏥 Post-Surgery Considerations

This medicine may be prescribed before and after eye surgery to prevent infection. Follow your surgeon's instructions carefully regarding dosing and duration.

🦷 Dental Procedures

There are no specific considerations for dental procedures while using this medicine. However, inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Avoid touching or rubbing your eyes to prevent spreading the infection.
🥗
Wash your hands frequently, especially before and after applying eye drops.
😴
Do not share towels, pillows, or eye makeup with others.
💧
Replace your eye makeup and contact lenses after the infection clears.
🧘
Follow good hygiene practices to prevent reinfection.

🏋️ Exercise Considerations

There are no specific exercise restrictions while using this medicine. However, if you have blurred vision after applying the drops, avoid activities that require clear vision, such as swimming or contact sports, until your vision clears.

🥗 Diet Recommendations

Stay well hydrated to support overall eye health.
Include foods rich in vitamin A and omega-3 fatty acids, such as carrots, spinach, and fish.
Avoid excessive caffeine and alcohol, which can contribute to dehydration.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision after application. Wait until your vision is clear before driving or operating heavy machinery. You can continue your normal daily activities, but avoid touching your eyes and maintain good hand hygiene to prevent spreading the infection.

🛑 When to Stop This Medicine

Stop using this medicine only after completing the full course prescribed by your doctor, even if your symptoms improve. If you experience a serious allergic reaction or severe eye pain, stop using it and seek immediate medical attention. Do not stop or change the dose without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless directed by a doctor. Prolonged use can lead to overgrowth of non-susceptible organisms, including fungi, and may increase the risk of antibiotic resistance. If you need to use this medicine for an extended period, your doctor will monitor you for signs of superinfection.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Warm compresses

Applying a warm compress to the affected eye can help relieve discomfort and reduce swelling.

Evidence: Well-established
Good hygiene

Frequent hand washing and avoiding touching the eyes can help prevent the spread of infection.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations while using this medicine, but consult your doctor if you have any concerns.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, keep it in your carry-on luggage in its original packaging. Carry a copy of your prescription to show at customs if needed. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, continue your dosing schedule as prescribed, but consult your doctor if you need to adjust the timing. Do not leave the bottle in a hot car or in direct sunlight.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with bacterial conjunctivitis
She noticed redness, itching, and a sticky discharge in her right eye. Her doctor prescribed this medicine, and she used it as directed. Within two days, the redness and discharge reduced significantly. She completed the full 7-day course and the infection cleared completely.
💡 Lesson: Using the medicine exactly as prescribed and completing the full course helps clear the infection and prevents recurrence.
👤 A 60-year-old man with a corneal ulcer
He experienced severe eye pain and blurred vision after an eye injury. He was diagnosed with a corneal ulcer and started on this medicine with frequent dosing. He followed the schedule strictly and attended follow-up visits. The ulcer healed over two weeks without complications.
💡 Lesson: For serious eye infections like corneal ulcers, strict adherence to the dosing schedule and regular follow-up with an eye doctor are crucial for recovery.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start to feel better within 1 to 2 days, but it is important to complete the full course as prescribed.

Q: Can I use this medicine for viral eye infection?

A: No, this medicine is only effective against bacterial infections. It will not treat viral or fungal eye infections.

Q: Is this medicine safe for children?

A: The safety and effectiveness of this medicine in children under 1 year of age have not been established. Consult a pediatrician.

Q: Can I wear contact lenses while using this medicine?

A: You should remove contact lenses before using this medicine and wait at least 15 minutes before reinserting them, unless your doctor advises otherwise.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine for viral eye infection?
  • How long should I use this medicine?
  • Can I wear contact lenses while using this medicine?
  • Is this medicine safe for children?
  • What should I do if I miss a dose?
  • Can I use this medicine if I am pregnant?

🔄 Substitutes for zyquin 400mg infusion

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any eye infection.
    Fact: This medicine is only effective against bacterial eye infections. It does not treat viral or fungal infections.
  • Myth: You can stop using this medicine as soon as your symptoms improve.
    Fact: You should complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: This medicine is safe to use for dry eyes.
    Fact: This medicine is not a lubricant and should not be used for dry eyes. It is an antibiotic and should only be used for bacterial infections.

🔄 Alternative Options

Generic Alternatives

  • Gatifloxacin ophthalmic solution 0.3%

Brand Alternatives

  • Algat eye drop

📊 Comparison with Similar Medicines

[{"medicine":"Gatifloxacin eye drops","class":"Fluoroquinolone antibiotic","spectrum":"Broad-spectrum","dosing":"Every 2 hours initially, then 4 times daily"},{"medicine":"Ciprofloxacin eye drops","class":"Fluoroquinolone antibiotic","spectrum":"Broad-spectrum","dosing":"Every 2 hours initially, then 4 times daily"},{"medicine":"Ofloxacin eye drops","class":"Fluoroquinolone antibiotic","spectrum":"Broad-spectrum","dosing":"Every 2-4 hours initially, then 4 times daily"}]

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