Doltan H 12.5mg/20mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Decreased urine output or swelling in legs
- Irregular heartbeat or palpitations
- Severe abdominal pain or vomiting
- Signs of allergic reaction: rash, itching, swelling of face or throat
- Yellowing of skin or eyes
- Persistent muscle cramps or weakness
If experiencing severe symptoms, call emergency services immediately.
What is xirtam h tablet used for?
This medicine is a combination of hydrochlorothiazide and olmesartan medoxomil used to treat high blood pressure. It works by reducing fluid volume and relaxing blood vessels.
- Generic Name: Hydrochlorothiazide (12.5mg) + Olmesartan Medoxomil (20mg)
- Manufacturer: Bayer Zydus Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 xirtam h tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। यह हाइड्रोक्लोरोथियाजाइड और ओल्मेसार्टन मेडोक्सोमिल का संयोजन है। यह शरीर से अतिरिक्त नमक और पानी को बाहर निकालने में मदद करती है और रक्त वाहिकाओं को आराम देती है, जिससे रक्तचाप कम होता है। यह दवा स्ट्रोक और दिल के दौरे के खतरे को कम करने में भी मदद करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी, गुर्दे की समस्या, इलेक्ट्रोलाइट असंतुलन और बहुत कम रक्तचाप शामिल हो सकते हैं। यदि आपको मांसपेशियों में कमजोरी, भ्रम, पेशाब कम आना या सूजन हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार सही समय पर लें, आमतौर पर दिन में एक बार। बिना डॉक्टर की सलाह के इसे अचानक बंद न करें। शराब से बचें क्योंकि इससे चक्कर बढ़ सकते हैं। पर्याप्त पानी पिएं। नियमित रूप से रक्तचाप, गुर्दे की कार्यप्रणाली और इलेक्ट्रोलाइट्स की जांच कराएं। गर्भवती होने या गर्भधारण की योजना बनाने पर डॉक्टर को सूचित करें।
💊 xirtam h tablet Uses & Benefits
[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults, reducing the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Hypertension
Also treats: Heart failure, Diabetic nephropathy
📋 Drug Information
| Generic Name(s) | Hydrochlorothiazide (12.5mg) + Olmesartan Medoxomil (20mg) |
| Brand Name | xirtam h tablet |
| Manufacturer | Bayer Zydus Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antihypertensive agents with complementary mechanisms. Hydrochlorothiazide inhibits the sodium-chloride symporter in the distal convoluted tubule of the kidney, increasing excretion of sodium, chloride, and water, which reduces plasma volume and cardiac output. Olmesartan medoxomil is a prodrug that is hydrolyzed to olmesartan, which selectively blocks angiotensin II type 1 (AT1) receptors, preventing angiotensin II-mediated vasoconstriction and aldosterone secretion. Together, they lower blood pressure more effectively than either agent alone.
Mechanism Steps
💡 How to Take xirtam h tablet
Strength: Tablet containing 12.5 mg hydrochlorothiazide and 20 mg olmesartan medoxomil.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet once daily, with or without food. The dose may be adjusted by your doctor based on your blood pressure response and tolerability. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor closely for dizziness and electrolyte imbalances. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose adjustment may be needed. Not recommended if eGFR <30 mL/min. |
| Hepatic Impairment | Use with caution in patients with mild to moderate liver impairment. Not recommended in severe liver disease. |
| Maximum Daily Dose | One tablet daily (12.5 mg hydrochlorothiazide + 20 mg olmesartan medoxomil). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of xirtam h tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Lithium | Major | |
| NSAIDs | Major | |
| Potassium-sparing diuretics | Major | |
| Corticosteroids | Moderate | |
| Digoxin | Moderate |
🚨 Major Interactions
- Lithium
- Potassium-sparing diuretics
- NSAIDs
⚡ Moderate Interactions
- Corticosteroids
- Digoxin
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect and increase dizziness. Avoid or limit alcohol consumption.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy","Anuria","Hypersensitivity to hydrochlorothiazide, olmesartan, or sulfonamide-derived drugs","Severe liver disease","Severe kidney disease (eGFR
⚠️ Warnings & Precautions
["May cause dizziness; avoid driving until you know how it affects you.","Monitor for signs of electrolyte imbalance.","Avoid potassium supplements without medical advice.","Use with caution in patients with gout or lupus.","May worsen kidney function in dehydrated patients."]
🤱 Lactation Safety
Hydrochlorothiazide passes into breast milk and may affect milk production. Olmesartan is present in breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe hypotension, electrolyte imbalances, and dehydration. Seek emergency medical attention. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed, usually once daily with or without food. Do not stop suddenly without consulting your doctor. Avoid alcohol as it can worsen dizziness. Stay hydrated, especially in hot weather or during exercise. Regular monitoring of blood pressure, kidney function, and electrolytes is essential. Inform your doctor if you become pregnant or plan to become pregnant. Do not use potassium supplements without medical advice.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects and electrolyte imbalances. Start with a lower dose and monitor closely.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative before conception.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist about this medicine before surgery. It may need to be temporarily stopped to prevent blood pressure fluctuations during surgery.
🦷 Dental Procedures
Inform your dentist about this medicine. It may cause dry mouth or dizziness during dental procedures. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is beneficial but avoid strenuous activity in hot weather to prevent dehydration and dizziness. Stay hydrated and rise slowly from sitting or lying positions.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, especially when starting treatment. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their daily activities with caution.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Your doctor may adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use may require regular monitoring of kidney function, electrolytes, and blood pressure. Electrolyte imbalances and kidney problems can occur. Periodic blood tests are recommended. Do not stop the medicine without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight loss can help lower blood pressure and complement medicine.
Evidence: Well-establishedACE inhibitors, calcium channel blockers, or beta-blockers may be alternatives.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip and carry it in your hand luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 1-2 weeks, with maximum effect in about 4 weeks.
A: Yes, it can be taken with or without food. Taking it at the same time daily is important.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for xirtam h tablet
View AllAlternative brands with exact same active ingredient:
-
ol h 12.5mg/20mg tabletDavaindia Generic Pharmacy ₹27.00 72.3% CHEAPER
-
olmezem 20 h tabletZeelab Pharmacy Pvt Ltd ₹32.00 67.2% CHEAPER
-
Rasotan H 12.5mg/20mg TabletEmcure Pharmaceuticals Ltd ₹35.00 64.1% CHEAPER
-
StayHappi Hydrochlorothiazide+Olmesartan Medoxomil 12.5mg/20mg TabletSarvagunaushdhi Pvt Ltd ₹37.50 61.5% CHEAPER
-
ezisartan-oh tabletDR Best pharmaceuticals Pvt Ltd ₹48.00 50.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often requires long-term treatment. Do not stop without consulting your doctor. - Myth: This medicine causes kidney damage in everyone.
Fact: Kidney problems are rare and usually occur in patients with pre-existing kidney disease or those taking certain other medicines.
🔄 Alternative Options
Generic Alternatives
- Hydrochlorothiazide + Olmesartan Medoxomil