vzith a 500mg/30mg tablet - Azithromycin (500mg) + Ambroxol (30mg) medicine

Aedizith A 500mg/30mg Tablet: Complete Medicine Guide

No reviews yet
🏭 Vatican Life Sciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for the individual components in their respective indications.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or wheezing
  • Severe skin rash with blisters or peeling
  • Yellowing of the skin or eyes
  • Severe or bloody diarrhea
  • Irregular or very fast heartbeat
  • Sudden fainting or severe dizziness
  • Decreased urine output or swelling in the legs

If experiencing severe symptoms, call emergency services immediately.

What is vzith a 500mg/30mg tablet used for?

This medicine is a combination of azithromycin, an antibiotic, and ambroxol, a mucus thinner. It is used to treat bacterial respiratory infections with thick mucus. The usual adult dose is one tablet once daily for 3 to 5 days, as prescribed by a doctor.

  • Generic Name: Azithromycin (500mg) + Ambroxol (30mg)
  • Manufacturer: Vatican Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 vzith a 500mg/30mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एज़िथ्रोमाइसिन और एम्ब्रोक्सोल का संयोजन है। एज़िथ्रोमाइसिन एक एंटीबायोटिक है जो बैक्टीरिया को मारता है, और एम्ब्रोक्सोल बलगम को पतला करता है ताकि उसे खांसकर बाहर निकालना आसान हो। इसका उपयोग बैक्टीरियल श्वसन संक्रमण जैसे ब्रोंकाइटिस, निमोनिया और साइनसाइटिस के इलाज के लिए किया जाता है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में पेट खराब होना, जी मिचलाना, दस्त, पेट दर्द, सिरदर्द और स्वाद में बदलाव शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, लीवर की समस्या, अनियमित दिल की धड़कन और त्वचा पर गंभीर दाने हो सकते हैं। अगर कोई भी दुष्प्रभाव गंभीर लगे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। एंटासिड के साथ इस दवा को न लें, कम से कम 2 घंटे का अंतर रखें। शराब न पिएं क्योंकि इससे पेट की परेशानी और चक्कर बढ़ सकते हैं। अगर आपको लीवर या किडनी की समस्या है तो डॉक्टर को बताएं। चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई या गंभीर दाने होने पर तुरंत मेडिकल हेल्प लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 vzith a 500mg/30mg tablet Uses & Benefits

[{"condition":"Acute bacterial bronchitis","description":"This medicine helps clear bacterial infection and thins mucus, making it easier to cough out.","evidence":"Well-established"},{"condition":"Bacterial pneumonia","description":"Used for community-acquired pneumonia when azithromycin-sensitive bacteria are suspected, with ambroxol aiding mucus clearance.","evidence":"Well-established"},{"condition":"Acute bacterial sinusitis","description":"Treats bacterial sinus infection and helps relieve thick nasal discharge.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD) exacerbation","description":"May be used when a bacterial infection triggers a flare-up, with ambroxol helping to loosen mucus.","evidence":"Moderate"},{"condition":"Productive cough with thick mucus","description":"Ambroxol component helps thin and clear thick mucus, while azithromycin treats any underlying bacterial infection.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Bronchiectasis with recurrent infection","description":"Sometimes prescribed to reduce exacerbations and improve mucus clearance.","evidence":"Limited"},{"condition":"Cystic fibrosis airway clearance","description":"Ambroxol may be used off-label as a mucolytic, but azithromycin use requires specialist oversight.","evidence":"Limited"}]

Primary treatment for: Bacterial respiratory tract infections

Also treats: Acute bronchitis, Bacterial pneumonia, Acute sinusitis, COPD exacerbation

📋 Drug Information

Generic Name(s)Azithromycin (500mg) + Ambroxol (30mg)
Brand Namevzith a 500mg/30mg tablet
ManufacturerVatican Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep the tablets in their original blister pack or container.
Shelf Life24 months from the date of manufacture, or as printed on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food if it causes stomach upset.
2
Complete the full course even if you feel better after a few days.
3
Avoid taking antacids within 2 hours of this medicine.
4
Do not drink alcohol while taking this medicine.
5
Stay well hydrated to help thin mucus and flush out the infection.
6
Report any signs of liver problems like yellowing of eyes or dark urine immediately.
7
Do not share this medicine with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
Fever with chest congestion
May be used if bacterial infection is suspected.
Likely Use
Runny nose without fever
This medicine is not for viral colds.
Not Primary
Sore throat without bacterial signs
Not a primary treatment for viral sore throat.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAzithromycin is absorbed from the gastrointestinal tract after oral administration, with a bioavailability of approximately 37%. Ambroxol is rapidly absorbed from the gastrointestinal tract after oral administration. Food may slightly delay absorption but does not significantly reduce the total amount absorbed.
DistributionAzithromycin distributes widely into body tissues, with high concentrations in the lungs, tonsils, and prostate. It accumulates inside cells, which helps it target intracellular bacteria. Ambroxol also distributes into lung tissue and airway secretions, where it exerts its mucolytic effect.
Protein BindingAzithromycin is about 7% to 50% bound to plasma proteins, depending on concentration. Ambroxol is approximately 90% bound to plasma proteins.
MetabolismAzithromycin is metabolized in the liver, mainly by CYP3A4, into inactive metabolites. Ambroxol is metabolized in the liver by glucuronidation and some oxidation.
Half-LifeAzithromycin has a long terminal elimination half-life of about 68 hours, which allows for once-daily dosing and a short treatment course. Ambroxol has a shorter half-life of approximately 7 to 12 hours.
ExcretionAzithromycin is excreted mainly in bile as unchanged drug and metabolites, with a small amount excreted in urine. Ambroxol is excreted mainly in urine as metabolites.
BioavailabilityAzithromycin oral bioavailability is approximately 37%. Ambroxol oral bioavailability is approximately 70% to 80%.
Onset of ActionAzithromycin begins to reduce bacterial growth within a few hours, but noticeable symptom improvement usually takes 24 to 48 hours. Ambroxol starts thinning mucus within 30 to 60 minutes of taking a dose.
Peak Plasma TimeAzithromycin reaches peak plasma concentration about 2 to 3 hours after oral administration. Ambroxol reaches peak plasma concentration about 1 to 2 hours after oral administration.
Duration of ActionAzithromycin has a long tissue half-life, so its antibacterial effect lasts for several days after the last dose. Ambroxol's mucolytic effect lasts about 6 to 8 hours per dose.

How It Works

Azithromycin works by binding to the 50S ribosomal subunit of susceptible bacteria, blocking the translocation step of protein synthesis and stopping bacterial growth. Ambroxol increases the production of surfactant in the lungs, which reduces mucus viscosity and helps cilia move mucus out of the airways. It also has mild local anesthetic and antioxidant properties that soothe irritated airways.

Mechanism Steps

1
Azithromycin binds to bacterial ribosome: Azithromycin attaches to the 50S subunit of the bacterial ribosome, preventing the bacteria from making essential proteins.
2
Bacterial protein synthesis stops: Without new proteins, the bacteria cannot grow or multiply, and the immune system can clear the infection.
3
Ambroxol increases surfactant: Ambroxol stimulates surfactant production in the lungs, which lowers mucus stickiness.
4
Mucus becomes thinner: Thinner mucus is easier for the cilia to move upward and for the patient to cough out.
5
Airway clearance improves: Better mucus clearance reduces coughing fits and helps the patient breathe more comfortably.

💡 How to Take vzith a 500mg/30mg tablet

Strength: Each immediate-release tablet contains azithromycin 500 mg and ambroxol 30 mg.

1Take the tablet by mouth with a full glass of water.
2You may take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole; do not crush, chew, or break it.
4Take it at the same time each day to maintain steady levels.
5Do not take antacids within 2 hours of this medicine.
6Complete the full course prescribed by your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken once daily by mouth, with or without food, for a duration determined by your doctor based on the type and severity of infection. The typical course for respiratory infections is 3 to 5 days, but your doctor may prescribe a different duration. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate or adjust the dose without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially heart rhythm changes and hearing problems. Your doctor may start with a lower dose or monitor you more closely. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentNo dose adjustment is usually needed for mild to moderate kidney impairment. In severe kidney disease (creatinine clearance less than 10 mL/min), azithromycin should be used with caution and the dose may need to be adjusted by your doctor. Ambroxol does not require dose adjustment in kidney disease.
Hepatic ImpairmentAzithromycin should be used with caution in patients with liver disease. Your doctor may reduce the dose or avoid this medicine if you have severe liver impairment. Ambroxol is generally safe but should be used cautiously in severe liver disease.
Maximum Daily DoseThe maximum recommended daily dose is one tablet containing azithromycin 500 mg and ambroxol 30 mg. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Antacids
Avoid within 2 hours
Antacids can reduce absorption of azithromycin.
Alcohol
Avoid
May worsen dizziness and stomach upset.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of vzith a 500mg/30mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take the tablet with food or milk to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated with oral rehydration fluids. Avoid fatty or spicy foods. Consult a doctor if diarrhea is severe or bloody.
Abdominal pain (Common (5-10%))
Take with food and avoid alcohol. If pain is severe or persistent, seek medical advice.
Headache (Common (5-10%))
Rest and stay hydrated. Consult a doctor if the headache is severe or does not go away.
Altered taste (Uncommon (1-5%))
This usually resolves after finishing the course. Chewing sugar-free gum may help.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe skin rash.
Liver injury (Rare (<0.1%))
Stop the medicine and contact your doctor right away if you notice yellowing of the skin or eyes, dark urine, or severe abdominal pain.
Irregular heartbeat (QT prolongation) (Rare (<0.1%))
Seek immediate medical attention if you feel palpitations, dizziness, or fainting.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Go to the emergency room if you develop a painful rash with blisters, peeling skin, or sores in the mouth or eyes.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Contact your doctor if you have severe, persistent diarrhea, especially with blood or mucus, even weeks after finishing the antibiotic.

⚠️ Rare Side Effects

Torsades de pointes
Seek emergency care for sudden fainting or irregular heartbeat.
Pancreatitis
Go to the hospital if you have severe upper abdominal pain that radiates to your back.
Interstitial nephritis
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Hearing loss (reversible)
Inform your doctor if you notice ringing in the ears or reduced hearing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Amiodarone Major
Digoxin Major
Ergotamine Major
Antacids Moderate
Carbamazepine Moderate
Phenytoin Moderate
Cyclosporine Moderate
Cimetidine Minor
Theophylline Minor

🚨 Major Interactions

  • Warfarin
  • Amiodarone
  • Digoxin
  • Ergotamine

⚡ Moderate Interactions

  • Antacids (aluminium/magnesium)
  • Carbamazepine
  • Phenytoin
  • Cyclosporine

🍷 Alcohol Interaction

Alcohol may worsen stomach upset, dizziness, and drowsiness caused by this medicine. It is best to avoid alcohol while taking this medicine and for at least 48 hours after finishing the course.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to azithromycin, ambroxol, or other macrolide antibiotics","History of cholestatic jaundice or liver problems caused by azithromycin","Severe liver disease","Myasthenia gravis (azithromycin can worsen muscle weakness)","Use with caution in patients with QT prolongation or a history of torsades de pointes"]

⚠️ Warnings & Precautions

["Do not use this medicine for viral infections like the common cold or flu; it will not help and may cause harm.","Complete the full course prescribed by your doctor, even if you feel better early.","Tell your doctor if you have liver, kidney, or heart problems before taking this medicine.","Avoid taking antacids within 2 hours of this medicine.","Do not drink alcohol while taking this medicine.","Stop the medicine and seek immediate medical help if you develop signs of a severe allergic reaction.","If you develop severe or bloody diarrhea, contact your doctor; this may be a sign of a serious bowel infection.","This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you."]

🤱 Lactation Safety

Azithromycin passes into breast milk in small amounts and is generally considered compatible with breastfeeding. Ambroxol also passes into breast milk in small amounts. Monitor the baby for diarrhea, vomiting, or rash, and consult your doctor if you notice any changes.

💊 Overdose Management

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe nausea, vomiting, diarrhea, stomach pain, and hearing loss. Treatment is supportive and symptomatic. There is no specific antidote. Contact your local poison control center or go to the nearest emergency room.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not share it with others or save leftover tablets for later use. Complete the full course even if symptoms improve early. Avoid taking antacids containing aluminium or magnesium within two hours of this medicine, as they can reduce absorption. Tell your doctor about all other medicines you take, especially blood thinners, heart rhythm medicines, and other antibiotics. Do not drink alcohol while taking this medicine because it can worsen stomach upset and dizziness. If you have liver or kidney problems, your doctor may need to adjust the dose or monitor you more closely. Stop the medicine and seek immediate medical help if you develop swelling of the face or throat, difficulty breathing, or a severe skin rash.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more likely to experience side effects such as heart rhythm changes, hearing problems, and liver issues. Your doctor may monitor you more closely and adjust the dose based on kidney and liver function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. Azithromycin and ambroxol are generally considered safe when clearly needed, but the decision should be made by your doctor.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medications used during surgery. Your doctor will decide if you can continue it.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with antibiotics or other medicines prescribed by the dentist. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier or take steam inhalation to ease breathing.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get plenty of rest to help your body fight the infection.
🧘
Wash your hands frequently to prevent spreading infection.
🌞
Eat a balanced diet rich in fruits and vegetables.

🏋️ Exercise Considerations

You may feel tired or dizzy while taking this medicine. Avoid strenuous exercise until you feel better. Light activities like walking are fine if you feel up to it. Consult your doctor before resuming intense workouts.

🥗 Diet Recommendations

Drink warm fluids like soups and herbal teas.
Include vitamin C rich foods like oranges and amla.
Avoid cold drinks and ice cream.
Eat light, easily digestible meals.
Include turmeric and ginger for their anti-inflammatory properties.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tiredness in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue desk work, but take breaks and stay hydrated.

🛑 When to Stop This Medicine

Stop this medicine and contact your doctor immediately if you experience signs of a severe allergic reaction, liver problems, irregular heartbeat, or severe diarrhea. Do not stop the medicine early just because you feel better, as this can lead to recurrence of infection and antibiotic resistance.

📅 Long-Term Use Effects

This medicine is usually prescribed for a short course of 3 to 5 days. Long-term use is not recommended because it can increase the risk of antibiotic resistance, liver problems, and heart rhythm changes. If you need treatment for more than a few days, your doctor will monitor your liver and heart function.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and ease breathing.

Evidence: Well-established
Saline nasal irrigation

Can help clear nasal congestion in sinusitis.

Evidence: Moderate
Chest physiotherapy

Helps clear mucus in chronic respiratory conditions.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are due for a vaccine, inform your doctor. Antibiotics do not affect vaccine efficacy, but your doctor may prefer to wait until you recover from the acute infection.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid extreme temperatures. If traveling across time zones, continue taking it at the same time each day or as advised by your doctor. Check customs regulations for carrying prescription medicines in your destination country. Store away from direct sunlight and moisture during travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis and thick mucus
He was prescribed this medicine for 5 days. He took it with breakfast every morning. By day 3, his cough became more productive and his chest felt less congested. He completed the full course and recovered fully.
💡 Lesson: Taking the medicine with food and completing the course led to a smooth recovery.
👤 A 60-year-old woman with COPD exacerbation
She started this medicine along with her regular inhalers. She noticed less breathlessness and easier coughing within 2 days. She reported mild nausea, which improved when she took the tablet after meals.
💡 Lesson: Taking the tablet after meals can reduce nausea, and combining with inhalers helps overall breathing.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course prescribed by your doctor.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is this medicine safe during pregnancy?

A: Azithromycin and ambroxol are generally considered safe during pregnancy when clearly needed, but you must consult your doctor before taking any medicine.

Q: Can I drink alcohol while taking this medicine?

A: It is best to avoid alcohol because it can worsen side effects like dizziness and stomach upset.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe to take with other antibiotics?
  • Does it cause drowsiness?

🔄 Substitutes for vzith a 500mg/30mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine is an antibiotic and does not work against viruses. It should only be used for bacterial infections.
  • Myth: You can stop taking this medicine as soon as you feel better.
    Fact: You must complete the full course to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This is a prescription medicine. Self-medication can lead to incorrect use, side effects, and antibiotic resistance.
  • Myth: Taking this medicine with alcohol is safe.
    Fact: Alcohol can worsen side effects like stomach upset and dizziness. It is best to avoid alcohol while taking this medicine.

🔄 Alternative Options

Generic Alternatives

  • Azithromycin 500 mg + Ambroxol 30 mg tablet (generic)

Brand Alternatives

  • Aedizith A 500mg/30mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Azithromycin 500 mg alone","difference":"Lacks ambroxol; does not thin mucus."},{"medicine":"Ambroxol 30 mg alone","difference":"Lacks azithromycin; does not treat bacterial infection."},{"medicine":"Azithromycin 250 mg + Ambroxol 30 mg","difference":"Lower azithromycin strength; may be used for milder infections."}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory