Azedim 250mg Injection (Ceftazidime): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe or persistent diarrhea, abdominal cramps, or fever
- Seizures or convulsions
- Decreased urine output or swelling in the legs
- Severe rash with blistering or peeling skin
- Yellowing of the skin or eyes
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is vizidime 250mg injection used for?
This medicine is a cephalosporin antibiotic injection containing Ceftazidime 250mg. It is used to treat serious bacterial infections by killing the bacteria that cause them. It is given by a healthcare professional and is not for viral infections.
- Generic Name: Ceftazidime (250mg)
- Manufacturer: Biovista Lifesciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 vizidime 250mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफ्टाजिडाइम 250mg इंजेक्शन है, जिसका उपयोग गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह तीसरी पीढ़ी का सेफलोस्पोरिन एंटीबायोटिक है। यह निमोनिया, मूत्र मार्ग संक्रमण, त्वचा संक्रमण, रक्त संक्रमण, मस्तिष्क ज्वर और बुखार के साथ कम श्वेत रक्त कोशिका वाले रोगियों में उपयोग किया जाता है। यह दवा बैक्टीरिया को मारकर काम करती है और इसे डॉक्टर द्वारा इंजेक्शन के रूप में दिया जाता है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, लालिमा या सूजन, दस्त, मतली, उल्टी, पेट दर्द, सिरदर्द और चक्कर आना शामिल हैं। कुछ लोगों को हल्के दाने या खुजली हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज बुखार, गंभीर दस्त, दौरे, गुर्दे की समस्या, और गंभीर एलर्जी प्रतिक्रियाएं जैसे सांस लेने में कठिनाई, चेहरे या गले में सूजन शामिल हो सकती हैं। यदि आपको कोई भी गंभीर लक्षण महसूस हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं कि आपको सेफलोस्पोरिन, पेनिसिलिन या किसी अन्य एंटीबायोटिक से एलर्जी है या नहीं। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर रक्त पतला करने वाली दवाएं, मूत्रवर्धक और अन्य एंटीबायोटिक्स। यदि आपको गुर्दे की बीमारी है, तो आपके डॉक्टर को खुराक समायोजित करने की आवश्यकता हो सकती है। यह दवा इंजेक्शन द्वारा दी जाती है, इसलिए इसे स्वयं न लें। यदि आप गर्भवती या स्तनपान करा रही हैं, तो अपने डॉक्टर से जोखिम और लाभ पर चर्चा करें। इस दवा को लेते समय शराब से बचें। किसी भी नए लक्षण जैसे गंभीर दस्त, दाने, या सांस लेने में कठिनाई की तुरंत रिपोर्ट करें। संक्रमण को फिर से होने से रोकने के लिए अपने डॉक्टर द्वारा बताई गई पूरी खुराक लें।
💊 vizidime 250mg injection Uses & Benefits
[{"condition":"Lower respiratory tract infections","description":"Used to treat pneumonia and bronchitis caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against complicated and uncomplicated urinary tract infections.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats infections such as cellulitis, abscesses, and wound infections.","evidence":"Well-established"},{"condition":"Bacteremia","description":"Used for bloodstream infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Meningitis","description":"Effective in treating bacterial meningitis, often in combination with other antibiotics.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"Used as empirical therapy in patients with low white blood cell counts and fever.","evidence":"Well-established"},{"condition":"Bone and joint infections","description":"Used to treat osteomyelitis and septic arthritis.","evidence":"Well-established"},{"condition":"Gynecological infections","description":"Effective against pelvic inflammatory disease and endometritis.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Melioidosis","description":"Sometimes used off-label for melioidosis, a bacterial infection common in tropical regions.","evidence":"Limited"},{"condition":"Cystic fibrosis exacerbations","description":"May be used off-label for pulmonary exacerbations in cystic fibrosis patients.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Pneumonia, Urinary tract infections, Skin infections, Bacteremia, Meningitis, Febrile neutropenia
📋 Drug Information
| Generic Name(s) | Ceftazidime (250mg) |
| Brand Name | vizidime 250mg injection |
| Manufacturer | Biovista Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Parenteral (intravenous or intramuscular injection) |
| Storage | Store this medicine in its original packaging at room temperature, between 15°C and 30°C. Protect it from light and moisture. Do not freeze. Once reconstituted, the solution should be used within the time specified by the manufacturer, typically within 24 hours if stored at room temperature or 7 days if refrigerated. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture. Check the expiry date on the packaging before use. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to specific proteins called penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final step of cell wall synthesis, leading to a weakened cell wall and ultimately causing the bacteria to die. It is bactericidal, meaning it kills bacteria directly. Ceftazidime is stable against many beta-lactamases, enzymes that bacteria produce to resist antibiotics, but it can be hydrolyzed by extended-spectrum beta-lactamases (ESBLs).
Mechanism Steps
💡 How to Take vizidime 250mg injection
Strength: This medicine is available as a sterile powder for injection in a 250mg strength. It must be reconstituted before use.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 250mg to 2 grams administered every 8 to 12 hours, depending on the type and severity of the infection. For uncomplicated urinary tract infections, a dose of 250mg every 12 hours may be sufficient. For more serious infections, higher doses such as 1 to 2 grams every 8 hours may be used. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may have reduced kidney function, which can affect the elimination of this medicine. Dose adjustment may be necessary based on kidney function. Your doctor will determine the appropriate dose. |
| Renal Impairment | In patients with renal impairment, the dose of this medicine should be adjusted based on creatinine clearance. For patients with a creatinine clearance of 31-50 mL/min, the usual dose may be given every 12 hours. For creatinine clearance of 16-30 mL/min, the dose may be given every 24 hours. For creatinine clearance of 6-15 mL/min, the dose may be given every 24 hours, and for patients on dialysis, a loading dose followed by maintenance doses after dialysis is recommended. Always consult your doctor for precise dosing. |
| Hepatic Impairment | No specific dosage adjustment is required for patients with hepatic impairment alone. However, if both hepatic and renal impairment are present, dose adjustment may be needed based on renal function. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 6 grams per day for adults with normal kidney function. Doses higher than this are not recommended. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of vizidime 250mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aminoglycosides | Major | |
| Loop diuretics | Major | |
| Warfarin | Major | |
| Chloramphenicol | Moderate | |
| Probenecid | Moderate | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Aminoglycosides (e.g., gentamicin)
- Loop diuretics (e.g., furosemide)
- Warfarin
⚡ Moderate Interactions
- Chloramphenicol
- Probenecid
🍷 Alcohol Interaction
Alcohol may increase the risk of certain side effects such as nausea, dizziness, and stomach upset. It is advisable to avoid alcohol while receiving this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to ceftazidime or other cephalosporins","History of severe allergic reaction to penicillins or other beta-lactam antibiotics","Use in patients with a history of anaphylaxis to any beta-lactam antibiotic"]
⚠️ Warnings & Precautions
["Before starting this medicine, inform your doctor about any allergies, especially to antibiotics.","Use with caution in patients with kidney disease. Dose adjustment may be required.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","This medicine may cause false-positive results in certain urine glucose tests.","It may also interfere with certain blood tests for creatinine.","Do not use this medicine for viral infections as it is ineffective.","If you develop severe diarrhea, contact your doctor immediately as it may be a sign of a serious intestinal infection."]
🤱 Lactation Safety
This medicine is excreted in human breast milk in low concentrations. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose of this medicine can cause symptoms such as seizures, encephalopathy, and neuromuscular excitability. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases, especially in patients with renal impairment.
⏰ Missed Dose
Since this medicine is usually given by a healthcare professional in a hospital or clinic setting, missed doses are unlikely. If you miss a scheduled dose, contact your healthcare provider as soon as possible. Do not attempt to self-administer a double dose.
Additional Safety Advice
Before receiving this medicine, tell your doctor if you are allergic to cephalosporins, penicillins, or any other antibiotics. Inform your doctor about all other medicines you are taking, especially blood thinners, diuretics, and other antibiotics. If you have kidney disease, your doctor may need to adjust your dose. This medicine is given by injection, so it must be administered by a healthcare professional. Do not attempt to self-administer. If you are pregnant or breastfeeding, discuss the risks and benefits with your doctor. Avoid alcohol while receiving this medicine as it may increase the risk of side effects. Report any new symptoms such as severe diarrhea, rash, or difficulty breathing immediately. Complete the full course as prescribed by your doctor, even if you feel better, to prevent the infection from returning.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can affect the elimination of this medicine. Dose adjustment based on kidney function is often necessary. Elderly patients may also be more susceptible to side effects such as confusion, seizures, and kidney problems. Close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before starting this medicine. This medicine is classified as Pregnancy Category B, meaning animal studies have not shown a risk to the fetus, but there are no adequate studies in pregnant women. It should be used during pregnancy only if clearly needed. If you become pregnant while taking this medicine, inform your doctor immediately.
🏥 Post-Surgery Considerations
This medicine is often used to prevent or treat infections after surgery. It is important to follow your surgeon's instructions regarding the duration and dose. Inform your surgeon if you have any allergies or kidney problems. Monitor for signs of infection at the surgical site and report any redness, swelling, or discharge.
🦷 Dental Procedures
If you are scheduled for a dental procedure, inform your dentist that you are receiving this medicine. This medicine may interact with certain antibiotics used in dentistry. Your dentist may need to adjust your treatment plan. Good oral hygiene is important to prevent infections.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While receiving this medicine, you may feel tired or dizzy. Avoid strenuous exercise until you feel fully recovered. Light activities like walking are generally safe, but listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery if you experience these effects. You may need to take time off work or school while receiving treatment, especially if you are hospitalized. Consult your doctor about when you can resume normal activities.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Even if you feel better, you must complete the full course as prescribed to prevent the infection from returning and to reduce the risk of antibiotic resistance. If you experience severe side effects, contact your doctor immediately; they will decide whether to stop the medicine or change the treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to overgrowth of non-susceptible organisms, including fungi, and may increase the risk of antibiotic resistance. Prolonged use may also affect kidney function and blood counts. Regular monitoring of kidney function, liver function, and blood counts may be required if used for an extended period. It is important to use this medicine only for the prescribed duration and not to self-medicate.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the infection and susceptibility, other antibiotics such as ceftriaxone, cefepime, or aminoglycosides may be used.
Evidence: Well-establishedRest, hydration, and fever control can complement antibiotic therapy.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines such as the typhoid vaccine. Avoid receiving live vaccines during treatment and for a short period after. Inactivated vaccines are generally safe to receive. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
If you need to travel while receiving this medicine, carry it in its original packaging with the prescription label. Keep a copy of your prescription with you. Since this medicine is given by injection, you will need to arrange for administration by a healthcare professional at your destination. Store it at room temperature and protect it from light. Check with the airline and customs about carrying injectable medicines. If traveling across time zones, consult your doctor about adjusting the dosing schedule.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 minutes to 1 hour after administration. You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.
A: No, this medicine is given by injection and must be administered by a healthcare professional in a hospital or clinic setting.
A: This medicine can affect kidney function, especially if you have pre-existing kidney disease or are taking other medicines that affect the kidneys. Your doctor will monitor your kidney function and adjust the dose if needed.
A: This medicine passes into breast milk in small amounts. It is generally considered safe, but consult your doctor to weigh the benefits and risks.
🤔 Common Patient Concerns
🔄 Substitutes for vizidime 250mg injection
View AllAlternative brands with exact same active ingredient:
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otax 250mg injectionDivine Lifecare Pvt Ltd ₹15.07 80.2% CHEAPER
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cefta 250mg injectionBeulah Biomedics Ltd ₹33.48 55.9% CHEAPER
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ceffguard 250mg injectionLeeMed Pharmaceuticals ₹44.00 42.1% CHEAPER
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nanocef 250mg injectionHauz Pharma Pvt Ltd ₹45.00 40.8% CHEAPER
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ozid 250mg injectionSwiss Pharma Pvt Ltd ₹46.88 38.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not work against viruses. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course as prescribed by your doctor to prevent the infection from returning and to avoid antibiotic resistance. - Myth: This medicine is safe for everyone.
Fact: This medicine is not safe for people with a known allergy to cephalosporins or penicillins. Always inform your doctor about your allergies.
🔄 Alternative Options
Generic Alternatives
- Ceftazidime injection
Brand Alternatives
- Azedim 250mg injection