Vitamin A (1000mg) + Thiamine(Vitamin B1) (5mg) + Vitamin B2 (1.4mg) + Vitamin D3 (10mg) + Pantothenic Acid (Vitamin B5) (2.5mg) (Medical Monograph)

Overview

A fixed-dose combination (FDC) of essential fat-soluble and water-soluble vitamins (A, D3, B1, B2, B5) formulated for the prevention and treatment of multiple vitamin deficiencies, particularly relevant in the Indian context where nutritional deficiencies are prevalent due to dietary habits, socioeconomic factors, and limited sun exposure. It supports immune function, energy metabolism, vision, bone health, and skin integrity.

Uses

  • Prevention and treatment of combined vitamin A, B-complex, and D deficiencies.
  • Nutritional support in individuals with inadequate dietary intake (e.g., restrictive diets, elderly).
  • Supplementation in conditions of increased demand (convalescence, post-illness, mild fatigue).

Side Effects

  • Nausea
  • Mild gastrointestinal discomfort
  • Headache (rare at these doses)

Detailed Pharmacology

This combination acts by replenishing essential cofactors and signaling molecules for fundamental biochemical pathways. Vitamin A (as Retinol) is critical for phototransduction (rhodopsin), epithelial cell differentiation, and immune function. Thiamine (B1) is a coenzyme (TPP) for carbohydrate metabolism (pyruvate dehydrogenase, transketolase). Riboflavin (B2) is a precursor for FMN and FAD, coenzymes for redox reactions. Vitamin D3 regulates calcium/phosphate homeostasis, promotes bone mineralization, and modulates immune response via the Vitamin D Receptor (VDR). Pantothenic Acid (B5) is a component of Coenzyme A, essential for fatty acid oxidation and synthesis.

Available Brands in India

BrandManufacturerPrice
Becozym Forte Roche Pharmaceuticals (now under license to various Indian companies) ₹80 - ₹150 for 30 tablets
Folvite Multivitamin Samarth Life Sciences Pvt. Ltd. ₹60 - ₹120 for 30 tablets
Becosules Capsules Pfizer Limited (Earlier), now manufactured by various Indian companies ₹70 - ₹140 for 30 capsules
Supradyn Multivitamin (Certain variants) Bayer India Limited ₹150 - ₹300 for 30 tablets
B-Vit Forte Cipla Ltd. ₹50 - ₹100 for 30 tablets