Imdur 60mg Tablet PR: Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe chest pain that does not go away with rest or usual medication
- Fainting or loss of consciousness
- Bluish discoloration of lips, skin, or nails
- Severe dizziness or lightheadedness
- Sudden swelling of face, lips, or throat
- Rapid or irregular heartbeat
- Shortness of breath
If experiencing severe symptoms, call emergency services immediately.
What is vasotrate od 60mg tablet used for?
This medicine is a nitrate used to prevent angina attacks. It works by relaxing blood vessels to improve blood flow to the heart. It is not for immediate relief of an acute attack.
- Generic Name: Isosorbide Mononitrate (60mg)
- Manufacturer: Torrent Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 vasotrate od 60mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एंजाइना (सीने में दर्द) के हमलों को रोकने के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को फैलाकर हृदय तक रक्त का प्रवाह बढ़ाती है और हृदय पर दबाव कम करती है। यह दवा तीव्र एंजाइना हमले के तत्काल उपचार के लिए नहीं है।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर लालिमा और मतली शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर निम्न रक्तचाप, बेहोशी और मेथेमोग्लोबिनेमिया शामिल हो सकते हैं। यदि आपको असामान्य लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अचानक बंद न करें। शराब से बचें। सिल्डेनाफिल जैसी दवाओं के साथ इसका सेवन न करें। उठते-बैठते समय धीरे-धीरे उठें ताकि चक्कर न आएं।
💊 vasotrate od 60mg tablet Uses & Benefits
[{"condition":"Prevention of angina pectoris","description":"This medicine is used for long-term prevention of angina attacks in patients with coronary artery disease.","evidence":"Well-established"},{"condition":"Chronic stable angina","description":"It helps reduce the frequency and severity of angina episodes when used regularly.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Heart failure with preserved ejection fraction","description":"Sometimes used off-label to reduce symptoms, but evidence is limited.","evidence":"Limited"},{"condition":"Esophageal spasm","description":"Occasionally used off-label to relieve esophageal spasm, but this is not a standard use.","evidence":"Limited"}]
Primary treatment for: Angina pectoris
Also treats: Coronary artery disease, Chronic stable angina
📋 Drug Information
| Generic Name(s) | Isosorbide Mononitrate (60mg) |
| Brand Name | vasotrate od 60mg tablet |
| Manufacturer | Torrent Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | NO Donors |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. |
| Shelf Life | Not established from the available information. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by releasing nitric oxide in the body. Nitric oxide activates an enzyme called guanylate cyclase, which increases cyclic GMP levels in smooth muscle cells. This leads to relaxation of vascular smooth muscle, especially in veins. The result is dilation of blood vessels, reduced preload and afterload on the heart, and improved blood flow to the heart muscle. This helps prevent angina attacks.
Mechanism Steps
💡 How to Take vasotrate od 60mg tablet
Strength: This medicine is available as a 60 mg extended-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 30 mg to 60 mg once daily, but the exact dose depends on the indication and patient response. Your doctor will individualize the dose based on your condition, age, and other factors. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely. |
| Renal Impairment | No specific dose adjustment is established for renal impairment. Use with caution and monitor. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution and monitor. |
| Maximum Daily Dose | The maximum recommended daily dose is 120 mg, but this should be determined by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of vasotrate od 60mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Tadalafil | Major | |
| Vardenafil | Major | |
| Riociguat | Major | |
| Alcohol | Moderate | |
| Beta-blockers | Moderate | |
| Calcium channel blockers | Moderate | |
| Diuretics | Moderate | |
| NSAIDs | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)
- Riociguat
⚡ Moderate Interactions
- Alcohol
- Antihypertensives (e.g., beta-blockers, calcium channel blockers)
- Diuretics
🍷 Alcohol Interaction
Alcohol can increase the blood pressure-lowering effect of this medicine and lead to severe dizziness, fainting, and low blood pressure. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to isosorbide mononitrate or other nitrates","Concomitant use with phosphodiesterase-5 inhibitors","Severe hypotension","Increased intracranial pressure","Severe anemia","Constrictive pericarditis","Hypertrophic obstructive cardiomyopathy"]
⚠️ Warnings & Precautions
["Do not use for acute angina attacks; use a fast-acting nitrate for immediate relief.","Tolerance to the effects can develop with continuous use; a nitrate-free interval is often recommended.","Avoid abrupt discontinuation as it may worsen angina.","Use with caution in patients with low blood pressure or dehydration.","May cause dizziness; avoid driving or operating machinery until you know how it affects you."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose can cause severe hypotension, headache, dizziness, and methemoglobinemia. Seek emergency medical attention immediately. Treatment is supportive and may include intravenous fluids, vasopressors, and methylene blue for methemoglobinemia.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly because this can worsen angina. Avoid alcohol because it can increase dizziness and low blood pressure. Do not take erectile dysfunction medicines such as sildenafil, tadalafil, or vardenafil while using this medicine. Rise slowly from sitting or lying positions to prevent dizziness. Keep a record of your angina attacks and inform your doctor if they become more frequent or severe. Store this medicine at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. They should start with a lower dose and be monitored closely for dizziness and falls.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with medications used during surgery and affect blood pressure. Your doctor may advise temporary discontinuation.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dizziness or low blood pressure during dental procedures. Your dentist may take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is beneficial for heart health, but avoid strenuous activities that trigger angina. Consult your doctor before starting any new exercise program. If you experience chest pain during exercise, stop immediately and rest.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or lightheadedness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities, but take precautions when rising from sitting or lying positions.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Abrupt discontinuation can worsen angina. Your doctor may adjust or stop the medicine based on your condition and response to treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance, where the medicine becomes less effective. To prevent this, doctors often recommend a nitrate-free interval of 10 to 12 hours each day. Regular monitoring of blood pressure and angina symptoms is important. Do not stop the medicine without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Heart-healthy diet, exercise, and stress management can complement medicine.
Evidence: Well-establishedBeta-blockers, calcium channel blockers, or ranolazine may be alternatives or add-ons.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Keep enough supply for your trip and carry it in your hand luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 to 60 minutes, but its full preventive effect may take a few days to develop.
A: Yes, but inform your doctor about all your medicines and conditions. Your doctor will decide if it is safe for you.
A: Headache is common when starting this medicine. It often improves with continued use. If it is severe or persistent, consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for vasotrate od 60mg tablet
View AllAlternative brands with exact same active ingredient:
-
davaindia isosorbide mononitrate 60mg tablet erDavaindia Generic Pharmacy ₹20.00 63.1% CHEAPER
-
angitab 60mg tablet srAbbott ₹35.85 33.8% CHEAPER
-
nican 60mg tablet crRaptakos Brett & Co Ltd ₹39.38 27.3% CHEAPER
-
isonit 60mg tablet srJohnlee Pharmaceuticals Pvt Ltd ₹42.53 21.4% CHEAPER
-
ihd 60mg tablet srStadmed Pvt Ltd ₹47.03 13.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for immediate relief of an angina attack.
Fact: This medicine is for prevention only. For immediate relief, use a fast-acting nitrate as prescribed. - Myth: It is safe to take erectile dysfunction medicines with this medicine.
Fact: Combining this medicine with erectile dysfunction medicines can cause dangerous low blood pressure and is contraindicated.
🔄 Alternative Options
Generic Alternatives
- Isosorbide mononitrate 60 mg extended-release tablets
Brand Alternatives
- Imdur 60 mg tablet PR