vagimycin vaginal capsule - Clindamycin (100mg) + Clotrimazole (200mg) medicine

anich 100mg/200mg Tablet VT: Complete Medicine Guide

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🏭 Medreich Lifecare Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for mixed infections; limited for some off-label uses.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe, persistent diarrhea or bloody stools
  • Severe abdominal pain or cramps
  • Signs of allergic reaction: rash, itching, swelling of face, lips, or throat, difficulty breathing
  • Yellowing of skin or eyes, dark urine
  • Unusual bleeding or bruising
  • Fever with chills
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is vagimycin vaginal capsule used for?

This medicine is a combination of clindamycin (an antibiotic) and clotrimazole (an antifungal) used to treat mixed bacterial and fungal skin infections. It works by stopping bacterial growth and killing fungi. It is available as a tablet and is taken orally, usually twice daily with food. It requires a prescription and should be taken exactly as directed.

  • Generic Name: Clindamycin (100mg) + Clotrimazole (200mg)
  • Manufacturer: Medreich Lifecare Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 vagimycin vaginal capsule के बारे में (Hindi Summary)

उपयोग: यह दवा क्लिंडामाइसिन और क्लोट्रिमाज़ोल का संयोजन है, जिसका उपयोग बैक्टीरियल और फंगल संक्रमणों के इलाज के लिए किया जाता है। यह त्वचा के मिश्रित संक्रमणों, जैसे कि संक्रमित दाद, और कुछ स्त्री रोग संबंधी संक्रमणों में प्रभावी है। यह दवा बैक्टीरिया के विकास को रोकती है और फंगस को मारती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, पेट दर्द, त्वचा पर चकत्ते, और धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभावों में गंभीर दस्त, एलर्जी प्रतिक्रिया, और यकृत की समस्या शामिल हो सकती है। यदि आपको गंभीर दस्त, पेट में तेज दर्द, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग डॉक्टर के निर्देशानुसार ही करें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। पूरा कोर्स पूरा करें, भले ही लक्षण ठीक हो गए हों। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। शराब का सेवन न करें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 vagimycin vaginal capsule Uses & Benefits

[{"condition":"Mixed bacterial and fungal skin infections","description":"Effective against infections caused by both bacteria and fungi, such as infected eczema or dermatitis.","evidence":"Well-established"},{"condition":"Infected dermatophytosis","description":"Treats fungal skin infections like ringworm that have become secondarily infected with bacteria.","evidence":"Well-established"},{"condition":"Candidiasis with secondary bacterial infection","description":"Used for skin or mucosal candidiasis complicated by bacterial infection.","evidence":"Moderate"},{"condition":"Bacterial vaginosis with fungal infection","description":"Sometimes used in gynecological practice for mixed infections.","evidence":"Limited"}]

Off-label uses: [{"condition":"Acne vulgaris with fungal component","description":"Occasionally prescribed off-label for acne with suspected fungal involvement.","evidence":"Limited"}]

Primary treatment for: Mixed bacterial and fungal skin infections

Also treats: Infected dermatophytosis, Candidiasis with secondary bacterial infection, Bacterial vaginosis with fungal infection

📋 Drug Information

Generic Name(s)Clindamycin (100mg) + Clotrimazole (200mg)
Brand Namevagimycin vaginal capsule
ManufacturerMedreich Lifecare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full prescribed course even if symptoms improve.
3
Stay well hydrated throughout the day.
4
Avoid alcohol while taking this medicine.
5
Do not share this medicine with others.
6
Report any unusual bleeding, bruising, or severe diarrhea immediately.
7
Store in a cool, dry place away from direct sunlight.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Skin rash with itching and redness
This medicine is commonly prescribed for mixed skin infections.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Cough
This medicine is not used for respiratory infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionClindamycin is absorbed from the gastrointestinal tract when taken orally; however, this medicine is a tablet for oral use. Clotrimazole is poorly absorbed from the gastrointestinal tract after oral administration, but when applied topically, it penetrates the outer skin layers. For this oral tablet, systemic absorption of clotrimazole is minimal.
DistributionClindamycin is widely distributed in body fluids and tissues, including bone. It crosses the placenta and is excreted in breast milk. Clotrimazole, when absorbed, is distributed to various tissues, but systemic distribution is limited due to poor oral absorption.
Protein BindingClindamycin is approximately 90% bound to plasma proteins. Clotrimazole is highly protein-bound (approximately 90-95%).
MetabolismClindamycin is metabolized in the liver, primarily by CYP3A4, to active and inactive metabolites. Clotrimazole is metabolized in the liver by CYP3A4 and other enzymes.
Half-LifeThe elimination half-life of clindamycin is approximately 2-3 hours. The half-life of clotrimazole is not well established for oral administration but is estimated to be around 2-5 hours for absorbed drug.
ExcretionClindamycin and its metabolites are excreted primarily in urine and feces. Clotrimazole metabolites are excreted mainly in feces via bile, with a small amount in urine.
BioavailabilityThe oral bioavailability of clindamycin is approximately 90%. Clotrimazole has very low oral bioavailability (less than 10%) due to poor absorption.
Onset of ActionThe onset of action for clindamycin is within 1-2 hours after oral administration. For clotrimazole, the onset of antifungal action is typically within 24-48 hours after starting therapy.
Peak Plasma TimeClindamycin reaches peak plasma concentrations in about 1 hour after oral administration. Clotrimazole peak plasma levels are low and variable.
Duration of ActionThe duration of action for clindamycin is about 6-8 hours per dose. For clotrimazole, the effect lasts as long as the drug is present at the site of infection, typically requiring multiple doses.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Clindamycin binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby stopping bacterial growth. Clotrimazole inhibits the synthesis of ergosterol, a vital component of fungal cell membranes, leading to increased membrane permeability and leakage of cellular contents, which results in fungal cell death.

Mechanism Steps

1
Clindamycin binding: Clindamycin binds to the 50S ribosomal subunit of bacteria, preventing peptide bond formation and inhibiting protein synthesis.
2
Clotrimazole action: Clotrimazole inhibits the fungal enzyme 14α-demethylase, blocking ergosterol synthesis and disrupting the fungal cell membrane.
3
Combined effect: The combined action leads to inhibition of bacterial growth and fungal cell death, resolving mixed infections.

💡 How to Take vagimycin vaginal capsule

Strength: Each tablet contains Clindamycin 100 mg and Clotrimazole 200 mg.

1Take this medicine orally with a full glass of water.
2Take it with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Complete the full course of therapy even if you feel better.
6Do not share this medicine with others.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally twice daily, or as directed by your physician. The dose may vary depending on the type and severity of the infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be necessary based on renal and hepatic function. Consult your doctor for appropriate dosing.
Renal ImpairmentIn patients with renal impairment, dose adjustment may be required. Clindamycin is excreted by the kidneys, and accumulation may occur. Consult your doctor for dose modification.
Hepatic ImpairmentIn patients with hepatic impairment, dose adjustment may be required. Clindamycin is metabolized in the liver. Monitor liver function closely. Consult your doctor for dose modification.
Maximum Daily DoseThe maximum recommended daily dose is 200 mg of clindamycin and 400 mg of clotrimazole (two tablets per day). Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of vagimycin vaginal capsule

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If persistent, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or bloody, seek medical attention immediately.
Abdominal pain (Common (5-10%))
Take with meals. If pain is severe or persistent, contact your doctor.
Skin rash (Uncommon (1-5%))
Discontinue use and consult your doctor if rash develops.
Metallic taste (Uncommon (1-5%))
Usually resolves on its own. Chewing sugar-free gum may help.

🚨 Serious Side Effects

Pseudomembranous colitis (Rare (<0.1%))
Seek immediate medical attention if you develop severe, persistent diarrhea, abdominal cramps, or fever.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Blood dyscrasias (Rare (<0.1%))
Inform your doctor if you notice unusual bleeding, bruising, or signs of infection.

⚠️ Rare Side Effects

Esophageal ulceration
Take with a full glass of water and remain upright for 30 minutes. Report chest pain or difficulty swallowing.
Polyarthritis
Consult a rheumatologist if joint pain and swelling occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Erythromycin Major
Neuromuscular blockers Major
Ketoconazole Moderate
Rifampin Moderate
Antacids Minor
Kaolin-pectin Minor
Grapefruit juice Moderate
Alcohol Moderate
Cyclosporine Moderate

🚨 Major Interactions

  • Warfarin
  • Neuromuscular blocking agents
  • Erythromycin

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)

🍷 Alcohol Interaction

Alcohol may increase the risk of gastrointestinal side effects such as nausea, vomiting, and abdominal pain. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to clindamycin, clotrimazole, or any component of the formulation","History of antibiotic-associated colitis","Severe liver disease","Severe kidney disease (requires dose adjustment)","Use in patients with a history of regional enteritis or ulcerative colitis"]

⚠️ Warnings & Precautions

["Use with caution in patients with a history of gastrointestinal disease, especially colitis.","May cause overgrowth of non-susceptible organisms, including fungi.","Prolonged use may result in superinfection.","Avoid use in patients with a history of asthma or allergic disorders.","Use with caution in elderly patients due to increased risk of adverse effects.","Do not use for viral infections.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Clindamycin is excreted in breast milk and may cause diarrhea or bloody stools in the nursing infant. Clotrimazole is unlikely to be excreted in significant amounts. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to low systemic absorption of clotrimazole. However, if overdose is suspected, seek immediate medical attention. Treatment is symptomatic and supportive. Gastric lavage may be considered if ingestion is recent. Monitor for signs of toxicity and manage accordingly.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Use this medicine exactly as prescribed by your doctor. Do not use it for longer than recommended or for other conditions. Wash your hands before and after applying the medicine. Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not cover the treated area with airtight dressings unless directed. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before using this medicine. Do not use this medicine without a prescription. Keep out of reach of children. If your symptoms do not improve within a few days or worsen, consult your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects such as diarrhea and electrolyte imbalances. Dose adjustment may be needed based on renal and hepatic function. Monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon about this medicine. It may interact with neuromuscular blocking agents used during anesthesia.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may increase the risk of bleeding during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hygiene to prevent reinfection.
🥗
Keep the affected area clean and dry.
😴
Avoid sharing personal items like towels or clothing.
💧
Wear loose-fitting cotton clothes to allow skin to breathe.
🧘
Follow a balanced diet to support immune function.
🌞
Get adequate rest to aid recovery.

🏋️ Exercise Considerations

If you experience dizziness or fatigue, avoid strenuous exercise until you feel better. Consult your doctor before resuming intense physical activity.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to maintain gut health.
Stay well hydrated.
Avoid spicy and oily foods if you have stomach upset.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. If affected, avoid driving or operating heavy machinery. Otherwise, it usually does not significantly impact daily activities.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early may lead to recurrence of infection and resistance. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to bacterial resistance and superinfections. Prolonged use of clindamycin can increase the risk of pseudomembranous colitis. Regular monitoring of liver and kidney function may be required. Use only for the prescribed duration and do not self-medicate.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical antifungal and antibacterial creams

May be used for localized skin infections.

Evidence: Well-established
Good hygiene practices

Helps prevent and manage skin infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your doctor about your vaccination status before starting this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust dosing times gradually under medical guidance. Check customs regulations for carrying prescription medicines. Always keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a mixed skin infection on her leg
She was prescribed this medicine for an infected fungal rash. After taking it with food twice daily for a week, her itching and redness significantly reduced. She completed the 14-day course and the infection cleared completely.
💡 Lesson: Taking the medicine with food and completing the full course led to successful treatment.
👤 A 50-year-old man with diabetes and a foot infection
He developed a bacterial and fungal infection on his foot. His doctor prescribed this medicine along with proper wound care. He noticed improvement within 5 days but continued the full course as advised. His infection resolved without complications.
💡 Lesson: Adhering to the prescribed duration and combining with good wound care is essential for healing.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start noticing improvement in symptoms within 2-3 days, but the full effect may take up to a week. Complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, it is recommended to take this medicine with food to reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe during pregnancy?

A: Consult your doctor before using this medicine during pregnancy. It should be used only if clearly needed.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol as it may increase the risk of gastrointestinal side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for vagimycin vaginal capsule

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any skin infection.
    Fact: It is only effective against specific bacterial and fungal infections. It does not treat viral or parasitic infections.
  • Myth: You can stop taking this medicine once symptoms improve.
    Fact: You must complete the full prescribed course to prevent recurrence and resistance.
  • Myth: This medicine is safe to use without a prescription.
    Fact: It is a prescription medicine and should only be used under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Clindamycin 100 mg + Clotrimazole 200 mg tablet

Brand Alternatives

  • anich 100mg/200mg tablet vt

📊 Comparison with Similar Medicines

[{"medicine":"anich 100mg/200mg tablet vt","composition":"Clindamycin 100 mg + Clotrimazole 200 mg","route":"Oral","primary_use":"Mixed bacterial and fungal infections"},{"medicine":"Clindamycin + Ketoconazole","composition":"Clindamycin + Ketoconazole","route":"Topical","primary_use":"Skin infections"},{"medicine":"Metronidazole + Clotrimazole","composition":"Metronidazole + Clotrimazole","route":"Vaginal","primary_use":"Vaginal infections"}]

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