Azigrand LB 500 Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe or bloody diarrhoea
- Swelling of face, lips, or throat
- Difficulty breathing or swallowing
- Yellowing of skin or eyes
- Dark urine or severe abdominal pain
- Irregular heartbeat or palpitations
- Severe skin rash with blisters or peeling
If experiencing severe symptoms, call emergency services immediately.
What is uzal lb 500mg tablet used for?
This medicine is a combination of azithromycin 500 mg, a macrolide antibiotic, and lactic acid bacillus 60 million spores, a probiotic. It is used to treat bacterial infections such as pneumonia, sinusitis, and skin infections. The probiotic helps prevent antibiotic-associated diarrhoea. It is taken orally once daily for 3–5 days as prescribed.
- Generic Name: Azithromycin (500mg) + Lactic acid bacillus (60Million spores)
- Manufacturer: Pluzine Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 uzal lb 500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एज़िथ्रोमाइसिन 500 मिलीग्राम और लैक्टिक एसिड बैसिलस 60 मिलियन स्पोर्स का संयोजन है। यह बैक्टीरियल संक्रमण जैसे निमोनिया, साइनसाइटिस, गले में संक्रमण, त्वचा संक्रमण और क्लैमाइडिया के इलाज के लिए इस्तेमाल की जाती है। इसमें मौजूद प्रोबायोटिक आंतों के अच्छे बैक्टीरिया को बनाए रखने में मदद करता है और एंटीबायोटिक से होने वाले दस्त को कम कर सकता है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द, सिरदर्द और स्वाद में बदलाव शामिल हैं। ये आमतौर पर हल्के होते हैं और दवा बंद करने पर ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे या गले में सूजन, सांस लेने में कठिनाई, पीलिया, या खूनी दस्त हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। टैबलेट को पानी के साथ पूरा निगलें, चबाएं नहीं। खाने के साथ या बिना खाने के ले सकते हैं, लेकिन पेट खराब हो तो हल्के भोजन के साथ लें। शराब न लें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। कोर्स पूरा करें, बीच में न छोड़ें।
💊 uzal lb 500mg tablet Uses & Benefits
[{"condition":"Community-acquired pneumonia","description":"Used to treat mild to moderate pneumonia caused by susceptible bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and Mycoplasma pneumoniae.","evidence":"Well-established"},{"condition":"Acute bacterial sinusitis","description":"Prescribed when sinusitis is confirmed or strongly suspected to be bacterial, helping to clear infection and reduce facial pain and congestion.","evidence":"Well-established"},{"condition":"Acute bacterial pharyngitis or tonsillitis","description":"Used as an alternative in patients allergic to penicillin, targeting Streptococcus pyogenes to prevent rheumatic fever complications.","evidence":"Well-established"},{"condition":"Uncomplicated skin and soft tissue infections","description":"Effective against many skin pathogens including Staphylococcus aureus and Streptococcus species when the infection is not severe.","evidence":"Well-established"},{"condition":"Urethritis and cervicitis due to Chlamydia trachomatis","description":"A single 1 g dose of azithromycin is a standard treatment for uncomplicated chlamydial infection, often combined with other therapy for gonorrhoea.","evidence":"Well-established"},{"condition":"Acute otitis media","description":"Used in patients allergic to penicillin or when first-line antibiotics are not suitable, for middle ear infections caused by susceptible bacteria.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Bronchiolitis obliterans syndrome after lung transplant","description":"Azithromycin has been used off-label for its immunomodulatory and anti-inflammatory effects in chronic lung allograft dysfunction.","evidence":"Limited"},{"condition":"Cystic fibrosis lung disease","description":"Long-term azithromycin may be prescribed to reduce exacerbations and improve lung function in selected patients with cystic fibrosis.","evidence":"Moderate"},{"condition":"Severe acne vulgaris","description":"Sometimes used off-label for its anti-inflammatory and antibacterial effects in acne that has not responded to standard treatments.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Community-acquired pneumonia, Acute bacterial sinusitis, Pharyngitis/tonsillitis, Skin and soft tissue infections, Chlamydial urethritis/cervicitis, Acute otitis media
📋 Drug Information
| Generic Name(s) | Azithromycin (500mg) + Lactic acid bacillus (60Million spores) |
| Brand Name | uzal lb 500mg tablet |
| Manufacturer | Pluzine Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | Typically 24 months from the date of manufacture, but refer to the packaging for the exact expiry date. |
| WHO Guideline | Azithromycin is included in the WHO Model List of Essential Medicines for the treatment of several bacterial infections, including sexually transmitted infections and respiratory tract infections. It is recommended as part of syndromic management of urethral discharge and for trachoma elimination programs. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) includes azithromycin in its treatment guidelines for community-acquired pneumonia, acute pharyngitis, and certain sexually transmitted infections. It is recommended as an alternative for patients allergic to penicillin. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Azithromycin binds to the 50S ribosomal subunit of susceptible bacteria and inhibits bacterial protein synthesis by blocking the translocation step of peptide chain elongation. This stops bacteria from making essential proteins, which prevents their growth and multiplication. The lactic acid bacillus is a live probiotic that helps restore and maintain beneficial gut flora, which can be disrupted by antibiotic therapy.
Mechanism Steps
💡 How to Take uzal lb 500mg tablet
Strength: Immediate-release oral tablet containing azithromycin 500 mg and lactic acid bacillus 60 million spores.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one 500 mg tablet taken once daily for 3 to 5 days, depending on the type and severity of infection. For uncomplicated chlamydial urethritis or cervicitis, a single 1 g dose (two 500 mg tablets) may be prescribed. For community-acquired pneumonia, a common regimen is 500 mg once daily for at least 3 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific 500 mg tablet formulation. Azithromycin is available in pediatric-friendly formulations, and dosing is based on body weight. Consult a pediatrician for appropriate dosing. |
| Elderly Dosage | Elderly patients may be more susceptible to QT prolongation and cardiac arrhythmias. No specific dose adjustment is required based on age alone, but caution is advised, and renal and hepatic function should be considered. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No dose adjustment is generally needed for mild to moderate renal impairment. In severe renal impairment (eGFR <10 mL/min), azithromycin should be used with caution; however, specific dose adjustments are not well established. Consult a nephrologist or clinical pharmacist. |
| Hepatic Impairment | No specific dose adjustment is established for mild to moderate hepatic impairment. Azithromycin is contraindicated in patients with a history of cholestatic jaundice or hepatic dysfunction associated with prior azithromycin use. Use with caution in severe liver disease. |
| Maximum Daily Dose | The maximum recommended daily dose is 500 mg for most indications, except for a single 1 g dose for chlamydial infection. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of uzal lb 500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ergotamine | Major | |
| Amiodarone | Major | |
| Antacids (Al/Mg) | Moderate | |
| Digoxin | Moderate | |
| Cyclosporine | Moderate | |
| Theophylline | Minor | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Warfarin
- Ergot alkaloids (e.g., ergotamine)
- Other QT-prolonging drugs (e.g., amiodarone, sotalol)
⚡ Moderate Interactions
- Antacids containing aluminium or magnesium
- Digoxin
- Cyclosporine
🍷 Alcohol Interaction
Alcohol may worsen stomach upset, nausea, and liver stress while taking this medicine. It is best to avoid alcohol until you finish the course and feel fully recovered.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to azithromycin, erythromycin, or any macrolide antibiotic","History of cholestatic jaundice or hepatic dysfunction associated with prior azithromycin use","Concurrent use with ergot alkaloids","Severe hepatic impairment"]
⚠️ Warnings & Precautions
["Use with caution in patients with prolonged QT interval or risk factors for arrhythmias.","Avoid in patients with myasthenia gravis as it may worsen muscle weakness.","May cause severe diarrhoea due to C. difficile; do not treat with anti-motility drugs without medical advice.","Monitor for signs of allergic reactions, including severe skin reactions.","Use with caution in patients with liver disease; discontinue if signs of hepatitis occur.","Probiotic component should be avoided in severely immunocompromised patients due to risk of infection."]
🤱 Lactation Safety
Azithromycin passes into breast milk in small amounts and is generally considered compatible with breastfeeding. Monitor the infant for diarrhoea, thrush, or rash. Consult your doctor before use.
💊 Overdose Management
Overdose may cause severe nausea, diarrhoea, and hearing loss. There is no specific antidote. Treatment is supportive and symptomatic. Contact a poison control centre or emergency department immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water; do not crush or chew it. You may take it with or without food, but if it upsets your stomach, take it with a light meal. Do not share this medicine with others, even if they have similar symptoms. Inform your doctor about all other medicines you take, especially antacids, warfarin, digoxin, and other antibiotics. Avoid alcohol while taking this medicine because it can worsen stomach upset and liver stress. If you are pregnant, planning pregnancy, or breastfeeding, tell your doctor before starting this medicine. Do not stop the course early unless your doctor advises you to. Store the tablet at room temperature away from moisture and direct sunlight. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of QT prolongation and cardiac arrhythmias. They should be monitored for signs of irregular heartbeat. Renal and hepatic function should be assessed before prescribing.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Azithromycin is generally considered safe when needed, but the decision should be made with your healthcare provider.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with certain anesthetic agents, and your doctor may advise stopping it before surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with certain antibiotics used in dentistry, and your dentist may need to adjust your treatment plan.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Mild exercise like walking is generally fine if you feel up to it, but avoid strenuous activity while you are recovering from an infection. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or visual disturbances in some people. If affected, avoid driving or operating heavy machinery. Most people can continue their normal daily activities, but rest is important for recovery.
🛑 When to Stop This Medicine
Stop taking this medicine only after completing the full prescribed course or if your doctor advises you to stop. If you experience severe side effects like allergic reactions, severe diarrhoea, or signs of liver problems, stop immediately and seek medical attention.
📅 Long-Term Use Effects
Long-term use of azithromycin is not recommended unless specifically prescribed for chronic conditions like cystic fibrosis. Prolonged use can lead to bacterial resistance, gut flora imbalance, and rarely liver or heart issues. Regular monitoring may be needed if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Essential supportive care for any infection.
Evidence: Well-establishedCan help relieve sinus congestion alongside antibiotics.
Evidence: LimitedMay help prevent antibiotic-associated diarrhoea.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Antibiotics do not interfere with most vaccines. However, if you are scheduled for a live bacterial vaccine (e.g., typhoid oral vaccine), antibiotics may reduce its efficacy. Consult your doctor about timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid temperature extremes. If crossing time zones, continue taking it at the same interval as prescribed; consult your doctor for specific advice. Store away from direct sunlight and moisture. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24–48 hours, but it is important to complete the full course as prescribed.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a light meal.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Azithromycin is generally considered acceptable during pregnancy when clearly needed. Consult your doctor before use.
A: It is best to avoid alcohol while taking this medicine as it can worsen stomach upset and liver stress.
🤔 Common Patient Concerns
🔄 Substitutes for uzal lb 500mg tablet
View AllAlternative brands with exact same active ingredient:
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vitazit 500mg tabletApkavit Lifesciences ₹60.84 9.9% CHEAPER
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zomy lb 500mg tabletTNT Lifesciences ₹61.00 9.6% CHEAPER
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Tziro 500 LB TabletOtik Biotec ₹62.81 6.9% CHEAPER
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arnicide az 500mg tabletArnvis Pharma Pvt Ltd ₹65.55 2.9% CHEAPER
-
azicepta 500mg tabletIncepta Pharma ₹66.00 2.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure the common cold and flu.
Fact: This medicine is effective only against bacterial infections, not viral infections like the common cold or flu. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full prescribed course to prevent bacterial resistance and relapse. - Myth: Probiotics in antibiotics are unnecessary.
Fact: The lactic acid bacillus in this medicine helps maintain gut health and may reduce antibiotic-associated diarrhoea. - Myth: Azithromycin is safe for everyone.
Fact: It is not safe for people with macrolide allergy, certain liver conditions, or those taking specific interacting drugs.
🔄 Alternative Options
Generic Alternatives
- Azithromycin 500 mg + Lactic acid bacillus 60 million spores tablet (various manufacturers)
Brand Alternatives
- Azithral 500 LB
- Azee 500 LB
- Zithrox 500 LB
- Azax 500 LB