Uriboost Solution: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular heartbeat or palpitations
- Severe muscle weakness or paralysis
- Difficulty breathing or shortness of breath
- Swelling of face, lips, or throat
- Black stools or vomiting blood
- Severe abdominal pain
- Decreased urine output
- Confusion or extreme fatigue
If experiencing severe symptoms, call emergency services immediately.
What is uriboost solution used for?
This medicine is a urinary alkalinizer containing citric acid and potassium citrate. It is used to treat and prevent uric acid and cystine kidney stones by making urine less acidic. It also helps correct metabolic acidosis. It is available as an oral solution and should be taken after meals with plenty of water.
- Generic Name: Citric Acid (334mg) + Potassium Citrate (1100mg)
- Manufacturer: Votary Laboratories I Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 uriboost solution के बारे में (Hindi Summary)
उपयोग: यह दवा मूत्र को क्षारीय बनाने वाली दवा है, जिसका उपयोग यूरिक एसिड और सिस्टीन की पथरी के इलाज और रोकथाम के लिए किया जाता है। यह मूत्र में एसिड की मात्रा को कम करके पथरी को घोलने में मदद करती है। यह मेटाबॉलिक एसिडोसिस के इलाज में भी उपयोगी है। इसका सेवन डॉक्टर के निर्देशानुसार भोजन के बाद पानी में मिलाकर किया जाता है।
साइड इफेक्ट्स: आम दुष्प्रभावों में पेट खराब होना, जी मिचलाना, दस्त और बार-बार पेशाब आना शामिल हैं। गंभीर दुष्प्रभावों में हाइपरकलेमिया (पोटेशियम का बढ़ना) हो सकता है, जिससे दिल की धड़कन अनियमित हो सकती है। अगर आपको मांसपेशियों में कमजोरी, सूजन या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप मात्रा न बढ़ाएं या घटाएं। दिनभर पर्याप्त पानी पिएं। पोटेशियम वाले सप्लीमेंट या नमक के विकल्प न लें। अगर आपको किडनी, हृदय या मधुमेह की समस्या है, तो डॉक्टर को बताएं। नियमित रूप से पोटेशियम और किडनी की जांच कराएं।
💊 uriboost solution Uses & Benefits
[{"condition":"Uric acid kidney stones","description":"Helps dissolve existing uric acid stones and prevents new stone formation by alkalinizing urine.","evidence":"Well-established"},{"condition":"Cystine kidney stones","description":"Increases urine pH to improve cystine solubility and reduce stone recurrence.","evidence":"Well-established"},{"condition":"Metabolic acidosis","description":"Corrects chronic metabolic acidosis by providing alkali equivalents.","evidence":"Well-established"},{"condition":"Distal renal tubular acidosis","description":"Used to treat the acidosis associated with this condition.","evidence":"Well-established"},{"condition":"Gout with hyperuricemia","description":"Adjunct therapy to reduce uric acid stone risk in patients with gout.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Urinary tract infection symptom relief","description":"May reduce burning sensation by alkalinizing urine, but not a primary treatment for infection.","evidence":"Limited"},{"condition":"Chemotherapy-induced hyperuricemia","description":"Rarely used to prevent uric acid nephropathy during tumor lysis syndrome.","evidence":"Limited"}]
Primary treatment for: Uric acid kidney stones
Also treats: Cystine kidney stones, Metabolic acidosis, Distal renal tubular acidosis, Gout
📋 Drug Information
| Generic Name(s) | Citric Acid (334mg) + Potassium Citrate (1100mg) |
| Brand Name | uriboost solution |
| Manufacturer | Votary Laboratories I Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the container tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by providing citrate ions that are metabolized to bicarbonate in the body. Bicarbonate acts as a buffer to neutralize excess hydrogen ions in the urine, thereby raising urinary pH. Citric acid is metabolized to bicarbonate, and potassium citrate directly supplies potassium and citrate. The increased urinary pH enhances the solubility of uric acid and cystine, preventing their precipitation into stones. Additionally, citrate inhibits calcium oxalate crystal aggregation, further reducing stone risk.
Mechanism Steps
💡 How to Take uriboost solution
Strength: Each 5 mL contains Citric Acid 334 mg and Potassium Citrate 1100 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 10-30 mL of solution diluted in water, taken 3 to 4 times daily after meals and at bedtime. The dose is adjusted based on urinary pH measurements, which should be maintained between 6.5 and 7.0 for uric acid stones and 7.0 to 7.5 for cystine stones. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to potassium retention. Start with a lower dose and monitor renal function and serum potassium closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Contraindicated in severe renal impairment (eGFR <30 mL/min). Consult a nephrologist for dosing. |
| Hepatic Impairment | No specific dose adjustment established. Use with caution in severe hepatic impairment. |
| Maximum Daily Dose | The maximum daily dose should not exceed 120 mL of solution per day, but individual limits must be set by a clinician based on monitoring. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of uriboost solution
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Spironolactone | Major | |
| Lisinopril | Major | |
| Ibuprofen | Moderate | |
| Aluminum hydroxide | Minor |
🚨 Major Interactions
- Potassium-sparing diuretics (e.g., spironolactone, amiloride)
- ACE inhibitors, ARBs
- Potassium supplements
⚡ Moderate Interactions
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Anticholinergic drugs
🍷 Alcohol Interaction
Alcohol may worsen dehydration and increase the risk of electrolyte imbalance. It is advisable to limit or avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Use with caution in patients with cardiac disease or hypertension.","Avoid in patients on potassium-sparing diuretics or ACE inhibitors without monitoring.","Do not use as a sole treatment for urinary tract infections.","May cause metabolic alkalosis if overused.","Monitor potassium levels regularly, especially in elderly and those with renal impairment."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Consult your doctor before using while breastfeeding.
💊 Overdose Management
Overdose may cause hyperkalemia, metabolic alkalosis, and gastrointestinal upset. Seek immediate medical attention. Treatment is symptomatic and supportive, including monitoring of electrolytes and cardiac function. In severe hyperkalemia, measures to lower potassium may be required.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Drink plenty of water throughout the day to help flush your urinary system and prevent stone formation. Avoid taking potassium supplements or salt substitutes containing potassium while on this medicine, as it can raise potassium levels dangerously. Inform your doctor if you have kidney disease, heart disease, Addison's disease, or diabetes, as these conditions may affect safe use. Do not use this medicine if you have a history of hyperkalemia or severe renal impairment. Regular blood tests to monitor potassium and kidney function are essential during treatment. Keep this medicine out of reach of children and store it as directed on the label.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of hyperkalemia and renal impairment. Dose should be adjusted based on renal function, and potassium levels should be monitored closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
After surgery, ensure adequate hydration and monitor electrolyte levels. Consult your surgeon before resuming this medicine, especially if you have been on intravenous fluids.
🦷 Dental Procedures
No specific precautions. Inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Stay well hydrated during exercise to prevent dehydration, which can concentrate urine and promote stone formation. Avoid strenuous exercise in extreme heat without adequate fluid intake.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause increased urination, which can affect work if you don't have easy access to restrooms. Plan your doses around your work schedule. It generally does not impair driving or operating machinery, but if you feel dizzy, avoid these activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Stopping abruptly may lead to recurrence of stones or worsening of acidosis. Your doctor will determine the appropriate duration based on your condition and response to treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. Regular monitoring of serum potassium, urinary pH, and renal function is necessary. Prolonged over-alkalinization may increase the risk of calcium phosphate stones. Periodic evaluation by a doctor is recommended to adjust the dose and assess the need for continued therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Reducing purine intake and increasing fluid intake can help manage uric acid stones.
Evidence: Well-establishedReduces uric acid production and may be used as an alternative or adjunct for uric acid stones.
Evidence: Well-establishedUsed for cystine stones to increase cystine solubility.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. Continue routine vaccinations as recommended by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If traveling across time zones, adjust dosing times gradually to maintain consistent intervals. Check customs regulations for carrying liquids and prescription medicines. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Urinary alkalinization begins within 1-2 hours after taking the medicine. However, the full benefits for stone prevention may take weeks to months.
A: Yes, it is recommended to take it after meals to reduce stomach upset.
A: Take it as soon as you remember if it's not too close to your next dose. Otherwise, skip it and continue with your regular schedule. Do not double dose.
A: No, you should avoid potassium supplements unless specifically directed by your doctor, as it can lead to dangerously high potassium levels.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of kidney stones.
Fact: It is effective mainly for uric acid and cystine stones, not for calcium oxalate stones. - Myth: You can take this medicine without monitoring.
Fact: Regular monitoring of urinary pH and potassium levels is essential. - Myth: It is safe to take extra doses for faster relief.
Fact: Taking more than prescribed can cause dangerous hyperkalemia.
🔄 Alternative Options
Generic Alternatives
- Potassium citrate and citric acid solution
- Potassium citrate oral solution
Brand Alternatives
- Uriboost Solution