Ultifix CV 250 mg/125 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing, wheezing, or swelling of the face, lips, tongue, or throat.
- Severe watery diarrhea, bloody stools, or persistent abdominal cramps with fever.
- A rapidly spreading skin rash, blisters, or sores in the mouth or eyes.
- Yellowing of the skin or eyes, dark urine, or pale stools.
- Unusual bruising or bleeding, or a persistent sore throat with fever.
- Decreased urine output, swelling of the legs, or blood in the urine.
- Chest pain, palpitations, or fainting.
- Seizures or confusion, especially in patients with kidney disease.
If experiencing severe symptoms, call emergency services immediately.
What is ultifix cv 250 mg/125 mg tablet used for?
This medicine is a prescription antibiotic that combines cefixime 250 mg with clavulanic acid 125 mg in an immediate-release tablet. It is used to treat certain bacterial infections of the respiratory tract, urinary tract, and skin when a clinician determines that susceptible bacteria are likely. It works by blocking bacterial cell wall formation and protecting cefixime from being broken down by bacterial enzymes. It should be taken exactly as prescribed, with food if it upsets the stomach, and the full course should be completed.
- Generic Name: Cefixime (250mg) + Clavulanic Acid (125mg)
- Manufacturer: Embiotic Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ultifix cv 250 mg/125 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेफिक्सिम और क्लैवुलैनिक एसिड का संयोजन है, जिसका उपयोग डॉक्टर द्वारा बताए गए कुछ बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह मुख्य रूप से श्वसन तंत्र के संक्रमण, मूत्र मार्ग के संक्रमण, और त्वचा या मुलायम ऊतकों के संक्रमण में दी जाती है। यह दवा बैक्टीरिया की कोशिका भित्ति बनने को रोककर उन्हें नष्ट करने में मदद करती है, और क्लैवुलैनिक एसिड कुछ बैक्टीरियल एंजाइमों से सेफिक्सिम की रक्षा करता है। यह दवा वायरल संक्रमण जैसे सर्दी-जुकाम या फ्लू के लिए नहीं है। इसे डॉक्टर की सलाह के अनुसार पूरा कोर्स करना बहुत जरूरी है, भले ही आप जल्दी ठीक महसूस करने लगें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट ढीला होना, जी मिचलाना, पेट में असहजता, सिरदर्द, और हल्के दाने शामिल हो सकते हैं। कुछ लोगों को पेट दर्द, उल्टी, या स्वाद में बदलाव भी महसूस हो सकता है। ये लक्षण अक्सर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। लेकिन अगर दस्त बहुत तेज हो, खून आए, सांस लेने में तकलीफ हो, चेहरे या गले में सूजन आए, या त्वचा पर तेजी से फैलने वाले दाने हों, तो तुरंत डॉक्टर से मिलें। बिना डॉक्टर की सलाह के दवा बंद न करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और किसी और के साथ साझा न करें। गोली को पूरे पानी के साथ निगलें, और अगर पेट में गड़बड़ी हो तो भोजन के साथ लें। अगर आपको कुछ दिनों में आराम महसूस होने लगे तो भी पूरा कोर्स पूरा करें, क्योंकि बीच में छोड़ने से संक्रमण फिर से हो सकता है और एंटीबायोटिक प्रतिरोध बढ़ सकता है। शराब न पिएं क्योंकि इससे पेट और लिवर से जुड़े दुष्प्रभाव बढ़ सकते हैं। गर्भावस्था, स्तनपान, या गर्भधारण की योजना बनाते समय डॉक्टर से सलाह लें। दवा को बच्चों से दूर, ठंडी और सूखी जगह पर, मूल पैकेजिंग में रखें।
💊 ultifix cv 250 mg/125 mg tablet Uses & Benefits
[{"condition":"Respiratory tract infections","description":"Used for susceptible bacterial infections of the upper and lower respiratory tract, including pharyngitis, tonsillitis, sinusitis, and acute bronchitis when a clinician confirms a bacterial cause.","evidence":"Well-established for susceptible organisms"},{"condition":"Urinary tract infections","description":"Prescribed for uncomplicated and some complicated urinary tract infections caused by susceptible bacteria, especially when beta-lactamase-producing organisms are suspected.","evidence":"Well-established for susceptible organisms"},{"condition":"Skin and soft tissue infections","description":"Used for certain bacterial skin infections such as cellulitis, abscesses, and wound infections when the responsible organisms are likely to be susceptible.","evidence":"Moderate evidence for susceptible organisms"},{"condition":"Otitis media","description":"Sometimes prescribed for middle ear infections in children and adults when a clinician determines that a susceptible bacterial infection is present.","evidence":"Moderate evidence for susceptible organisms"}]
Off-label uses: [{"condition":"Gonorrhea","description":"Cefixime-containing regimens have been used for uncomplicated gonorrhea, but clavulanic acid does not add benefit for this indication and local resistance patterns must be considered.","evidence":"Limited and guideline-dependent"},{"condition":"Typhoid fever","description":"Cefixime has been used for enteric fever in some settings, but rising resistance limits its reliability and combination with clavulanic acid is not standard for this purpose.","evidence":"Limited and region-dependent"}]
Primary treatment for: Susceptible bacterial infections, including respiratory tract infections, urinary tract infections, and skin and soft tissue infections.
Also treats: Otitis media, Sinusitis, Pharyngitis, Tonsillitis, Acute bronchitis
📋 Drug Information
| Generic Name(s) | Cefixime (250mg) + Clavulanic Acid (125mg) |
| Brand Name | ultifix cv 250 mg/125 mg tablet |
| Manufacturer | Embiotic Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral. This medicine is an immediate-release tablet that is swallowed whole with water. It should not be crushed, chewed, or broken unless your clinician or pharmacist advises otherwise |
| Storage | Store this medicine at room temperature between 15°C and 30°C in a dry place. Keep it in the original packaging to protect it from moisture and light. Do not store it in the bathroom or near a sink. Keep it out of reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture when stored as directed. Do not use it after the expiry date printed on the packaging. Check the packaging for the exact expiry date. |
| WHO Guideline | Not established from the available information for this specific combination. Antibiotic use should follow local and national guidelines, and clinicians should consider culture and susceptibility results when available. |
| ICMR Guideline | Not established from the available information for this specific combination. The Indian Council of Medical Research promotes rational antibiotic use and advises clinicians to prescribe antibiotics only when indicated and to complete the prescribed course. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary actions. Cefixime, the cephalosporin component, binds to penicillin-binding proteins inside the bacterial cell wall and blocks the cross-linking of peptidoglycan strands. This weakens the bacterial cell wall and leads to bacterial death. Clavulanic acid is a beta-lactamase inhibitor that protects cefixime from being destroyed by certain beta-lactamase enzymes produced by bacteria. Together, these actions allow cefixime to remain active against some bacteria that would otherwise be resistant to cefixime alone.
Mechanism Steps
💡 How to Take ultifix cv 250 mg/125 mg tablet
Strength: Immediate-release tablet containing cefixime 250 mg and clavulanic acid 125 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken once or twice daily, depending on the type and severity of the infection. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, kidney function, liver function, and the susceptibility of the infecting organism. Do not change the dose or stop treatment without consulting your clinician. Take the tablet with a full glass of water and with food if it upsets your stomach. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific tablet strength. Cefixime and clavulanic acid dosing in children depends on weight, age, kidney function, and the type of infection. Consult a pediatrician for appropriate dosing and formulation. |
| Elderly Dosage | Older adults may be more sensitive to the side effects of this medicine, especially stomach upset, diarrhea, and kidney-related effects. Kidney function often declines with age, so the clinician may adjust the dose or choose a different antibiotic. Older adults should stay well hydrated and report any new symptoms promptly. |
| Renal Impairment | This medicine is eliminated mainly by the kidneys, so patients with kidney impairment may need a lower dose or a longer dosing interval. The exact adjustment must be determined by a qualified clinician based on measured kidney function. Patients with severe kidney impairment should be monitored closely for side effects. |
| Hepatic Impairment | Patients with liver disease may need closer monitoring while taking this medicine. Clavulanic acid is partly metabolized in the liver, so liver function should be considered before prescribing. The exact dose adjustment, if any, must be determined by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose of this medicine is generally one tablet twice daily, but the exact maximum must be determined by a qualified clinician based on the indication, patient factors, and local prescribing guidance. Do not exceed the dose prescribed by your clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ultifix cv 250 mg/125 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Furosemide | Moderate | |
| Aminoglycosides | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor | |
| Allopurinol | Minor | |
| Live typhoid vaccine | Moderate |
🚨 Major Interactions
- Warfarin and other vitamin K antagonists
- Methotrexate
- Probenecid
⚡ Moderate Interactions
- Oral contraceptives
- Loop diuretics such as furosemide
- Aminoglycoside antibiotics
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Drinking alcohol can increase the risk of stomach upset, nausea, and liver-related side effects. It may also make it harder to judge whether symptoms are improving or worsening. If you drink alcohol regularly, discuss this with your clinician before starting treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergy or anaphylaxis to cefixime, other cephalosporins, clavulanic acid, or any component of this medicine.","Previous severe immediate allergic reaction to penicillins, because cross-reactivity with cephalosporins is possible.","Use in patients with a history of Clostridioides difficile-associated diarrhea after previous antibiotic use, unless the clinician decides the benefit outweighs the risk.","Use without medical supervision in pregnancy or breastfeeding unless specifically recommended by a clinician.","Use for viral infections such as the common cold or influenza, because this medicine is not effective against viruses."]
⚠️ Warnings & Precautions
["Tell your clinician about any allergy to antibiotics before starting this medicine.","Use with caution in patients with kidney disease, and follow any dose adjustment advised by the clinician.","Use with caution in patients with liver disease, and report symptoms of liver injury promptly.","Antibiotic-associated diarrhea can occur during or after treatment. Do not self-treat with anti-diarrheal medicines without medical advice.","This medicine may reduce the effectiveness of live bacterial vaccines such as the typhoid vaccine. Discuss timing with your clinician.","Do not share this medicine with others, even if they have similar symptoms.","Complete the full course prescribed, even if you feel better early, to reduce the risk of resistance.","Avoid alcohol during treatment to reduce stomach and liver-related side effects."]
🤱 Lactation Safety
Cefixime is excreted in small amounts in breast milk, and clavulanic acid is also present in breast milk. This medicine may be used during breastfeeding when prescribed by a clinician, but monitor the infant for diarrhea, thrush, or rash. If you notice any of these symptoms, contact your clinician.
💊 Overdose Management
Overdose with this medicine may cause nausea, vomiting, stomach pain, diarrhea, and, in severe cases, seizures or kidney problems. If you suspect an overdose, contact a poison control center or go to the nearest emergency department immediately. Do not try to induce vomiting unless instructed by a medical professional. Treatment is supportive and may include fluids, monitoring of kidney function, and management of seizures if they occur. Hemodialysis may be considered in severe cases with kidney failure, but this decision must be made by a qualified clinician.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided there is enough time before your next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your clinician or pharmacist for guidance.
Additional Safety Advice
Take this medicine exactly as prescribed by your clinician, and do not share it with anyone else. Swallow the tablet whole with a full glass of water, and take it with food if it upsets your stomach. Complete the entire course even if you start feeling better after a few days, because stopping early can allow the infection to come back. Tell your clinician about all other medicines, supplements, and herbal products you use, especially blood thinners, other antibiotics, and medicines for gout or stomach acid. Avoid alcohol while taking this medicine because it can worsen stomach upset and may increase the risk of liver-related side effects. If you are pregnant, planning pregnancy, or breastfeeding, speak with your clinician before using this medicine. Keep this medicine out of reach of children and store it in its original packaging away from heat, moisture, and direct sunlight. Contact your clinician right away if you develop a severe rash, swelling, breathing difficulty, or persistent diarrhea.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more likely to experience stomach upset, diarrhea, and kidney-related side effects from this medicine. Kidney function often declines with age, so the clinician may adjust the dose or choose a different antibiotic. Older adults should stay well hydrated and report any new symptoms, especially confusion, dizziness, or decreased urine output, to their clinician promptly.
🤰 Pregnancy Planning (TTC)
If you are trying to conceive or planning pregnancy, tell your clinician before taking this medicine. Cefixime is generally considered acceptable in pregnancy when clearly needed, but clavulanic acid data are more limited. Your clinician will weigh the benefits and risks. Do not start or stop this medicine without medical advice if you are pregnant or planning pregnancy.
🏥 Post-Surgery Considerations
If you are scheduled for surgery or have recently had surgery, tell your surgeon and anesthesiologist that you are taking this medicine. Antibiotics can interact with other medicines used during surgery and can affect wound healing and infection risk. Your surgical team will decide whether to continue, adjust, or temporarily stop this medicine.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. Antibiotics can affect the balance of bacteria in the mouth and may interact with other medicines used during dental work. Your dentist may coordinate with your clinician to decide whether any changes are needed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Mild activity such as walking is usually fine if you feel well enough. Avoid strenuous exercise or heavy lifting while you are recovering from an infection, especially if you have fever, fatigue, or muscle aches. If you feel dizzy, short of breath, or unusually tired, rest and contact your clinician. Return to your normal exercise routine gradually after your symptoms improve.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Most people can continue their usual daily activities while taking this medicine, but some may feel tired, nauseated, or have loose stools. Avoid driving or operating heavy machinery if you feel dizzy, drowsy, or unwell. If your work involves close contact with others, follow good hand hygiene and avoid sharing food or utensils. Inform your employer if you need time off to recover, especially if you have fever or severe symptoms.
🛑 When to Stop This Medicine
Do not stop this medicine on your own before completing the prescribed course, even if you feel better. Stopping early can allow the infection to return and can promote antibiotic resistance. If you develop a serious side effect such as a severe rash, difficulty breathing, or severe diarrhea, stop the medicine and seek medical help immediately. If you have questions about stopping, contact your clinician for guidance.
📅 Long-Term Use Effects
Long-term use of this medicine is not usually recommended unless a clinician is treating a specific persistent infection. Prolonged use can increase the risk of antibiotic resistance, stomach upset, diarrhea, and, rarely, liver or kidney problems. If long-term treatment is needed, your clinician may monitor your kidney function, liver function, and blood counts. Do not continue this medicine beyond the prescribed duration without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Testing can help identify the exact bacteria causing the infection and guide the choice of the most appropriate antibiotic.
Evidence: Well-establishedRest, fluids, and symptom relief can help while the infection resolves, but they do not replace antibiotics when a bacterial infection is confirmed.
Evidence: Well-establishedSome studies suggest probiotics may help reduce antibiotic-associated diarrhea, but evidence is mixed and they should not replace prescribed treatment.
Evidence: Limited to moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines, such as the oral typhoid vaccine. If you need a live bacterial vaccine, discuss the timing with your clinician. Inactivated vaccines are generally not affected by antibiotics. Do not stop this medicine to receive a vaccine without medical advice.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not store in the refrigerator unless specifically instructed.
✅ DO
Keep the tablets in their original blister pack or container.
❌ DON'T
Do not transfer them to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom or near a sink.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date printed on the pack.
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a letter from your clinician, especially for international travel, because some countries have strict rules about antibiotics. Store the tablets in a cool, dry place away from direct sunlight and moisture. If you are crossing time zones, ask your clinician how to adjust the dosing schedule. Do not pack this medicine in checked luggage if you need it during the flight; keep it in your hand baggage. Check local customs regulations before departure to avoid problems at the border.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 72 hours after starting this medicine, but it can take longer depending on the type and severity of the infection. Complete the full course prescribed by your clinician even if you feel better early.
A: Yes, this medicine can be taken with food, and taking it with a meal may help reduce stomach upset and nausea. Follow your clinician's instructions about timing.
A: It is best to avoid alcohol while taking this medicine because it can increase stomach upset and may add to liver-related side effects.
A: If you remember soon after the missed dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.
A: This medicine should be used during pregnancy only when a qualified clinician decides it is clearly needed. Do not self-medicate. Discuss the risks and benefits with your clinician.
A: No, this medicine is an antibiotic and does not work against viral infections such as the common cold or influenza. It should only be used for susceptible bacterial infections as prescribed.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: Antibiotics can cure the common cold and flu.
Fact: This medicine works only against susceptible bacteria and is not effective against viral infections such as the common cold or influenza. - Myth: You can stop this medicine as soon as you feel better.
Fact: Stopping early can allow the infection to return and can promote antibiotic resistance. Complete the full course prescribed by your clinician. - Myth: This medicine can be shared with family members who have similar symptoms.
Fact: This medicine is prescribed for a specific person and condition. Sharing it can be harmful and can lead to incorrect treatment. - Myth: Taking antibiotics with alcohol is always safe.
Fact: Alcohol can worsen stomach upset and may increase liver-related side effects. It is best to avoid alcohol during treatment.
🔄 Alternative Options
Generic Alternatives
- Cefixime 250 mg + Clavulanic Acid 125 mg tablet
Brand Alternatives
- ultifix cv 250 mg/125 mg tablet