Cilnidipine 10mg + Metoprolol Succinate 50mg Tablet: Complete Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Very slow heart rate (less than 50 beats per minute)
- Difficulty breathing or wheezing
- Swelling of face, lips, or throat
- Chest pain that worsens or does not go away
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is telma lnb 10mg/50mg/40mg tablet er used for?
This medicine is a combination of Cilnidipine and Metoprolol Succinate used to treat high blood pressure and angina. It works by relaxing blood vessels and slowing the heart rate. It is taken once daily as prescribed by a doctor.
- Generic Name: Cilnidipine (10mg) + Metoprolol Succinate (50mg)
- Manufacturer: Glenmark Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 telma lnb 10mg/50mg/40mg tablet er के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए इस्तेमाल की जाती है। यह सिल्निडिपिन और मेटोप्रोलोल सक्सिनेट का संयोजन है। सिल्निडिपिन रक्त वाहिकाओं को आराम देकर चौड़ा करता है, जिससे रक्तचाप कम होता है। मेटोप्रोलोल सक्सिनेट हृदय की गति को धीमा करता है और हृदय पर दबाव कम करता है। यह दवा आमतौर पर दिन में एक बार ली जाती है। इसे डॉक्टर के निर्देशानुसार ही लें, अपने आप बंद न करें।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे सिरदर्द, चक्कर आना, थकान, और टखनों में सूजन। कुछ लोगों को हाथ-पैर ठंडे लग सकते हैं या हृदय की गति धीमी हो सकती है। ये प्रभाव आमतौर पर हल्के होते हैं और समय के साथ ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको बेहोशी, सांस लेने में कठिनाई, या चेहरे पर सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर की सलाह पर ही लें। इसे रोज एक ही समय पर लें। गोली को पानी के साथ निगलें, चबाएं नहीं। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं। गाड़ी चलाते समय सावधानी बरतें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसे असर करती है। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को ठंडी और सूखी जगह पर रखें, बच्चों की पहुंच से दूर रखें।
💊 telma lnb 10mg/50mg/40mg tablet er Uses & Benefits
[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults, reducing the risk of heart attack, stroke, and kidney problems.","evidence":"Well-established"},{"condition":"Angina Pectoris","description":"It may be prescribed to prevent chest pain caused by reduced blood flow to the heart, known as angina.","evidence":"Well-established"},{"condition":"Chronic Stable Angina","description":"The combination can help reduce the frequency of angina attacks and improve exercise tolerance.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Heart Failure with Reduced Ejection Fraction","description":"Metoprolol Succinate, one component, is sometimes used off-label in stable heart failure, but the combination is not standard for this indication.","evidence":"Limited"},{"condition":"Migraine Prophylaxis","description":"Beta-blockers like Metoprolol are occasionally used off-label to prevent migraines, but this combination is not typically prescribed for this purpose.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Angina pectoris, Chronic stable angina
📋 Drug Information
| Generic Name(s) | Cilnidipine (10mg) + Metoprolol Succinate (50mg) |
| Brand Name | telma lnb 10mg/50mg/40mg tablet er |
| Manufacturer | Glenmark Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. Guidelines from the World Health Organization recommend combination therapy for hypertension in certain patients, but specific recommendations for this fixed-dose combination are not available. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research has guidelines for hypertension management, but specific recommendations for this combination are not available. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Cilnidipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle cells and cardiac myocytes. By blocking L-type calcium channels, it causes relaxation and widening of peripheral arteries, leading to reduced peripheral vascular resistance and lower blood pressure. Cilnidipine also blocks N-type calcium channels in sympathetic nerve terminals, which reduces the release of norepinephrine and further contributes to vasodilation and heart rate control. Metoprolol Succinate is a cardioselective beta-1 adrenergic receptor blocker. It reduces heart rate, myocardial contractility, and cardiac output, thereby lowering blood pressure and decreasing myocardial oxygen demand. The combination provides a synergistic effect: Cilnidipine reduces afterload, while Metoprolol reduces heart rate and contractility, leading to effective blood pressure control and reduced cardiac workload.
Mechanism Steps
💡 How to Take telma lnb 10mg/50mg/40mg tablet er
Strength: Tablet containing Cilnidipine 10 mg and Metoprolol Succinate 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, preferably in the morning. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, particularly dizziness, bradycardia, and hypotension. Start with a lower dose and titrate slowly. Regular monitoring of blood pressure, heart rate, and renal function is recommended. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is typically required. In severe renal impairment, dose reduction may be necessary. Monitor renal function regularly. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, dose reduction may be necessary. This medicine is contraindicated in severe hepatic impairment. Monitor liver function tests. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet of Cilnidipine 10 mg and Metoprolol Succinate 50 mg. Do not exceed this dose unless directed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of telma lnb 10mg/50mg/40mg tablet er
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Clonidine | Major | |
| MAOIs | Major | |
| Ketoconazole | Major | |
| NSAIDs | Moderate | |
| Fluoxetine | Moderate | |
| Digoxin | Moderate | |
| Oral antidiabetics | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Verapamil or Diltiazem
- Clonidine
- Monoamine oxidase inhibitors (MAOIs)
- CYP3A4 inhibitors (e.g., Ketoconazole, Itraconazole)
⚡ Moderate Interactions
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- CYP2D6 inhibitors (e.g., Fluoxetine, Paroxetine)
- Digoxin
- Oral antidiabetic agents
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can further lower blood pressure, increase dizziness, and enhance the sedative effects of Metoprolol. It may also worsen the side effects of Cilnidipine, such as headache and flushing. If you consume alcohol, discuss it with your doctor to understand the risks.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Cilnidipine, Metoprolol Succinate, or any component of the formulation.","Severe bradycardia (heart rate less than 50 beats per minute).","Second or third-degree heart block without a pacemaker.","Cardiogenic shock.","Decompensated heart failure.","Sick sinus syndrome without a pacemaker.","Severe peripheral arterial disease.","Untreated pheochromocytoma.","Severe hepatic impairment."]
⚠️ Warnings & Precautions
["Do not stop this medicine abruptly, as it can worsen angina or cause a heart attack. Taper the dose gradually under medical supervision.","Use with caution in patients with asthma or chronic obstructive pulmonary disease (COPD), as beta-blockers can cause bronchospasm.","May mask symptoms of hypoglycemia in diabetic patients. Monitor blood sugar regularly.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with peripheral vascular disease, as beta-blockers can worsen circulation.","Inform your doctor if you have a history of depression, as beta-blockers can worsen mood.","Avoid alcohol consumption as it can enhance the hypotensive and sedative effects.","Use with caution in elderly patients, who may be more sensitive to the effects of this medicine.","Inform your doctor if you are scheduled for surgery, as beta-blockers may interact with anesthetics.","This medicine may affect thyroid function tests; inform your doctor if you have thyroid disease."]
🤱 Lactation Safety
Not established from the available information. It is not known whether Cilnidipine or Metoprolol Succinate is excreted in human breast milk. Metoprolol is known to pass into breast milk in small amounts. Breastfeeding should be avoided or the medicine should be discontinued, depending on the importance of the drug to the mother. Consult your doctor for guidance.
💊 Overdose Management
Overdose of this medicine can cause severe hypotension, bradycardia, heart failure, bronchospasm, and hypoglycemia. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. Measures may include gastric lavage, administration of activated charcoal, intravenous fluids, atropine for bradycardia, and vasopressors for hypotension. Glucagon may be used for beta-blocker overdose. Monitor heart rate, blood pressure, and blood glucose closely.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
This medicine should only be taken under the supervision of a qualified healthcare professional. Do not start, stop, or change the dose without consulting your doctor. Take this medicine at the same time each day, preferably in the morning, to maintain consistent blood levels. Swallow the tablet whole with a glass of water; do not crush, chew, or break it. This medicine can cause dizziness, especially when you stand up quickly, so rise slowly from a sitting or lying position. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not consume alcohol while taking this medicine, as it can increase dizziness and lower your blood pressure further. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep all your medical appointments and get your blood pressure and heart rate checked regularly. Store this medicine in its original container, away from moisture and direct sunlight, and keep it out of reach of children. Do not share this medicine with anyone else, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to dizziness, bradycardia, and hypotension. Start with a lower dose and titrate slowly. Regular monitoring of blood pressure, heart rate, and renal function is advised. Falls risk may be increased due to dizziness.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established. Your doctor may switch you to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. Beta-blockers may interact with anesthetics and can affect heart rate and blood pressure during surgery. Do not stop the medicine without your doctor's advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with local anesthetics containing epinephrine, potentially causing hypertension or arrhythmias. Your dentist may adjust the anesthetic used.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine, but avoid sudden strenuous activities. If you experience dizziness, shortness of breath, or chest pain during exercise, stop and consult your doctor. Beta-blockers can reduce your maximum heart rate, so monitor your intensity using perceived exertion rather than heart rate alone.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal work activities with some adjustments. Inform your employer if your job involves operating machinery or working at heights.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects or your doctor decides to discontinue it, the dose will be tapered gradually to prevent rebound hypertension or angina. Always follow your doctor's instructions.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when taken under medical supervision. Regular monitoring of blood pressure, heart rate, and kidney and liver function is recommended. Prolonged use may lead to tolerance, but this is uncommon. Do not stop the medicine without consulting your doctor, as abrupt withdrawal can cause serious cardiovascular events.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can help control blood pressure and may reduce the need for medication.
Evidence: Well-establishedYour doctor may switch to a different combination if this medicine is not effective or causes side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. If crossing time zones, consult your doctor about adjusting the timing of your dose. Store it at room temperature and protect it from moisture. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within a few hours, but the full effect may take 1 to 2 weeks of regular use.
A: It is usually taken in the morning, but your doctor may advise a different time based on your condition.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, do not stop this medicine abruptly as it can worsen angina or cause a heart attack. Consult your doctor before stopping.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for telma lnb 10mg/50mg/40mg tablet er
View AllAlternative brands with exact same active ingredient:
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neodipine m tabletStrides shasun Ltd ₹66.96 51.8% CHEAPER
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cilozar m 10mg/50mg tabletSpectra Therapeutics Pvt Ltd ₹74.06 46.7% CHEAPER
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betabest cdp 10 mg/50 mg tabletMedley Pharmaceuticals ₹75.00 46% CHEAPER
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cadmet trio 10mg/50mg/40mg tabletLividus Pharmaceuticals Pvt Ltd ₹75.00 46% CHEAPER
-
corsa-m 10mg/50mg tabletAamorb Pharmaceuticals Pvt Ltd ₹79.50 42.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: Hypertension is a chronic condition. This medicine controls blood pressure but does not cure it. Stopping suddenly can cause dangerous rebound hypertension or angina. - Myth: This medicine causes kidney damage.
Fact: This medicine is used to protect the kidneys from damage caused by high blood pressure. However, regular monitoring is advised. - Myth: You can take this medicine with alcohol.
Fact: Alcohol can increase the blood pressure-lowering effect and cause dizziness. It is best to avoid alcohol. - Myth: This medicine is safe to take without a prescription.
Fact: This is a prescription medicine. It should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Cilnidipine 10 mg + Metoprolol Succinate 50 mg tablet