telma-d tablet sr - Telmisartan (40mg) + Indapamide (1.5mg) medicine

Inditel D Capsule SR: Complete Guide to Uses, Side Effects, and Safety

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🏭 Glenmark Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not recommended. This medicine can cause fetal harm, including oligohydramnios, fetal renal dysfunction, and death. Discontinue immediately if pregnancy is detected. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Swelling of face, lips, tongue, or throat
  • Difficulty breathing
  • Chest pain or irregular heartbeat
  • Decreased urine output or swelling in legs
  • Muscle pain, tenderness, or dark urine
  • Severe abdominal pain or vomiting
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is telma-d tablet sr used for?

This medicine is a combination of Telmisartan and Indapamide used to treat high blood pressure. It works by relaxing blood vessels and removing excess fluid from the body. It is taken once daily, usually in the morning.

  • Generic Name: Telmisartan (40mg) + Indapamide (1.5mg)
  • Manufacturer: Glenmark Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 telma-d tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। इसमें टेल्मिसार्टन और इंडापामाइड दो सक्रिय तत्व हैं जो मिलकर रक्तचाप को कम करते हैं। यह दवा रक्त वाहिकाओं को आराम देती है और शरीर से अतिरिक्त तरल पदार्थ निकालती है। इसे आमतौर पर दिन में एक बार सुबह लेने की सलाह दी जाती है। यह दवा उन रोगियों के लिए है जिनका रक्तचाप अकेले एक दवा से नियंत्रित नहीं हो पाता। गर्भवती महिलाओं, गुर्दे या लीवर की गंभीर बीमारी वाले मरीजों को यह दवा नहीं लेनी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान और हल्की मतली शामिल हैं। कुछ मरीजों में पेशाब बार-बार आना शुरू में हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी, गुर्दे की समस्या, इलेक्ट्रोलाइट असंतुलन और मांसपेशियों में दर्द शामिल हो सकते हैं। अगर आपको मांसपेशियों में दर्द, कमजोरी या गहरे रंग का पेशाब दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर दिन में एक बार सुबह। अचानक बंद न करें क्योंकि इससे रक्तचाप खतरनाक रूप से बढ़ सकता है। शराब से बचें क्योंकि इससे चक्कर और निम्न रक्तचाप बढ़ सकता है। पर्याप्त पानी पिएं। अगर आपको गुर्दे या लीवर की बीमारी, मधुमेह या गाउट है तो डॉक्टर को बताएं। पोटेशियम सप्लीमेंट या नमक के विकल्प बिना डॉक्टर की सलाह के न लें। गर्भावस्था की योजना बनाते समय या गर्भवती होने पर तुरंत डॉक्टर से मिलें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 telma-d tablet sr Uses & Benefits

  • [{"condition":"Essential hypertension","description":"This medicine is used to lower blood pressure in patients whose hypertension is not controlled by monotherapy.
  • It combines the blood pressure-lowering effects of Telmisartan and Indapamide.","evidence":"Well-established"},{"condition":"Hypertension with fluid retention","description":"The diuretic component helps reduce fluid overload, which can be beneficial in patients with mild heart failure or edema.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Heart failure with preserved ejection fraction","description":"Sometimes used off-label to manage blood pressure and fluid status in heart failure, but not a standard first-line indication.","evidence":"Limited"},{"condition":"Diabetic nephropathy","description":"Telmisartan has renoprotective effects, but the combination with Indapamide is not specifically approved for this use.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Heart failure, Diabetic nephropathy, Chronic kidney disease

📋 Drug Information

Generic Name(s)Telmisartan (40mg) + Indapamide (1.5mg)
Brand Nametelma-d tablet sr
ManufacturerGlenmark Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day, preferably in the morning, to establish a routine.
2
Monitor your blood pressure regularly at home and keep a log to share with your doctor.
3
Stay well hydrated, especially during hot weather or exercise, to prevent dehydration.
4
Avoid potassium supplements and salt substitutes unless approved by your doctor.
5
Report any muscle pain, weakness, or dark urine immediately, as these may be signs of a rare side effect.
6
Do not stop this medicine abruptly without consulting your doctor, even if you feel well.
7
Inform all healthcare providers, including dentists, that you are taking this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Fluid retention
The diuretic component helps reduce fluid retention.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTelmisartan is rapidly absorbed after oral administration, with peak plasma concentrations reached within 0.5 to 1 hour. Indapamide is also well absorbed from the gastrointestinal tract. Food slightly reduces the bioavailability of Telmisartan but does not significantly affect Indapamide. The sustained-release formulation of this medicine is designed to provide prolonged action.
DistributionTelmisartan is highly bound to plasma proteins and has a large volume of distribution. Indapamide is distributed widely in the body and binds to plasma proteins. Both agents cross the placental barrier and are excreted in breast milk.
Protein BindingTelmisartan: >99.5% bound to plasma proteins. Indapamide: approximately 70-80% bound to plasma proteins.
MetabolismTelmisartan is metabolized in the liver primarily by conjugation with glucuronic acid; no active metabolites are formed. Indapamide is extensively metabolized in the liver, with several inactive metabolites.
Half-LifeTelmisartan: approximately 24 hours. Indapamide: approximately 14-18 hours.
ExcretionTelmisartan is excreted mainly in the feces via bile, with less than 1% excreted unchanged in urine. Indapamide is excreted primarily in the urine (about 70%) and feces (about 30%).
BioavailabilityTelmisartan: approximately 42-58% after oral administration. Indapamide: approximately 93% after oral administration.
Onset of ActionBlood pressure lowering effect begins within 1-2 hours after oral administration, but maximum effect may take 2-4 weeks of regular use.
Peak Plasma TimeTelmisartan: 0.5-1 hour. Indapamide: 1-2 hours.
Duration of Action24 hours, allowing once-daily dosing.

How It Works

This medicine combines two antihypertensive agents with complementary mechanisms. Telmisartan selectively blocks angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release, which lowers blood pressure and reduces sodium retention. Indapamide is a thiazide-like diuretic that inhibits the sodium-chloride cotransporter in the distal convoluted tubule of the kidney, increasing excretion of sodium, chloride, and water. This reduces plasma volume and cardiac output initially, and later lowers peripheral vascular resistance. The combination provides additive blood pressure reduction.

Mechanism Steps

1
Telmisartan blocks AT1 receptors: Telmisartan binds to angiotensin II type 1 receptors in vascular smooth muscle and adrenal glands, preventing angiotensin II from causing vasoconstriction and aldosterone release.
2
Reduced vasoconstriction and aldosterone: Blockade of AT1 receptors leads to relaxation of blood vessels and decreased sodium and water retention, lowering blood pressure.
3
Indapamide inhibits sodium reabsorption: Indapamide acts on the distal convoluted tubule to inhibit the sodium-chloride cotransporter, increasing excretion of sodium, chloride, and water.
4
Diuresis and reduced plasma volume: Increased urine output reduces plasma volume and cardiac output, contributing to blood pressure reduction.
5
Long-term reduction in vascular resistance: Over time, the combination leads to a sustained decrease in peripheral vascular resistance, maintaining lower blood pressure.

💡 How to Take telma-d tablet sr

Strength: Capsule containing Telmisartan 40 mg and Indapamide 1.5 mg, sustained-release.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the capsule whole with a glass of water.
3Do not crush, chew, or open the capsule.
4Take it at the same time each day, preferably in the morning.
5You may take it with or without food, but taking it with food may reduce stomach upset.
6If you miss a dose, follow the missed dose instructions.
7Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one capsule once daily, preferably in the morning. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely for dizziness and falls. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Not recommended if eGFR is less than 30 mL/min. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. Contraindicated in severe hepatic impairment. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseOne capsule (Telmisartan 40 mg + Indapamide 1.5 mg) once daily. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
High-potassium foods
Moderate intake
May increase potassium levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of telma-d tablet sr

✅ Common Side Effects

Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid driving if dizzy. Consult doctor if persistent.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if severe or persistent.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue interferes with daily activities, consult your doctor.
Nausea (Common (1-5%))
Take with food. If nausea persists, consult your doctor.
Increased urination (Common (5-10%))
This is expected due to the diuretic effect. Take in the morning to avoid nighttime urination.

🚨 Serious Side Effects

Severe hypotension (Uncommon (0.1-1%))
Seek immediate medical attention if you experience fainting, severe dizziness, or blurred vision.
Acute kidney injury (Rare (<0.1%))
Report decreased urine output, swelling, or confusion to your doctor immediately.
Electrolyte imbalance (hypokalemia, hyponatremia) (Uncommon (0.1-1%))
Get regular blood tests. Report muscle cramps, weakness, or irregular heartbeat.
Severe allergic reaction (angioedema) (Rare (<0.1%))
Seek emergency care if you notice swelling of face, lips, tongue, or difficulty breathing.
Rhabdomyolysis (Very rare (<0.01%))
Report muscle pain, tenderness, or dark urine immediately.

⚠️ Rare Side Effects

Pancreatitis
Seek immediate care for severe abdominal pain radiating to the back.
Cholestatic jaundice
Report yellowing of skin or eyes to your doctor.
Agranulocytosis
Report fever, sore throat, or mouth ulcers immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Spironolactone Major
Lithium Major
Ibuprofen Major
ACE inhibitors Major
Corticosteroids Moderate
Digoxin Moderate
Metformin Moderate
Antacids Minor
Cholestyramine Minor
Alcohol Moderate

🚨 Major Interactions

  • Potassium-sparing diuretics (e.g., spironolactone)
  • Lithium
  • NSAIDs (e.g., ibuprofen)
  • ACE inhibitors

⚡ Moderate Interactions

  • Corticosteroids
  • Digoxin
  • Metformin

🍷 Alcohol Interaction

Alcohol can enhance the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, and falls. It is advisable to avoid alcohol or limit intake significantly while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","Anuria","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Monitor blood pressure regularly.","Avoid in pregnancy and breastfeeding.","Use with caution in patients with renal artery stenosis.","May cause dizziness; avoid driving until you know how it affects you.","Monitor electrolytes, especially potassium and sodium.","Avoid potassium supplements without medical advice.","Use with caution in patients with gout or history of gout.","May worsen systemic lupus erythematosus.","Do not use in children without specialist guidance."]

🤱 Lactation Safety

Not recommended. Telmisartan and Indapamide are excreted in breast milk and may cause adverse effects in the nursing infant. Consult your doctor for alternative treatments.

💊 Overdose Management

Overdose may cause severe hypotension, electrolyte imbalances, and dehydration. Treatment is supportive and symptomatic. If overdose is suspected, contact emergency services immediately. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and electrolytes closely.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed, usually once daily in the morning. Do not stop taking it suddenly without consulting your doctor, as this can cause a dangerous rise in blood pressure. Avoid alcohol, as it can worsen dizziness and low blood pressure. Stay well hydrated, especially in hot weather or during exercise. Inform your doctor if you have kidney or liver disease, diabetes, or gout. Do not use potassium supplements or salt substitutes containing potassium without medical advice. If you become pregnant or plan to become pregnant, contact your doctor immediately. Keep all follow-up appointments for blood pressure and blood test monitoring.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to dizziness, falls, and electrolyte imbalances. Start with a lower dose and monitor closely. Regular blood tests are recommended.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery due to its blood pressure-lowering and diuretic effects. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it may affect blood pressure and cause dizziness during dental procedures. Local anesthetics with epinephrine should be used with caution.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular physical activity, such as brisk walking or swimming.
😴
Reduce salt intake to less than 5 grams per day.
💧
Eat a diet rich in fruits, vegetables, and whole grains.
🧘
Limit alcohol and avoid smoking.
🌞
Manage stress through relaxation techniques like yoga or meditation.
🚭
Get adequate sleep and maintain a regular sleep schedule.

🏋️ Exercise Considerations

Exercise is generally safe while taking this medicine, but avoid strenuous activities in hot weather to prevent dehydration and low blood pressure. Stay hydrated and rise slowly from sitting or lying positions to avoid dizziness.

🥗 Diet Recommendations

Include potassium-rich foods like bananas, but monitor intake if you have kidney issues.
Reduce processed and high-sodium foods.
Stay well hydrated with water.
Limit caffeine and alcohol.
Eat a balanced diet with plenty of fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Take it in the morning to minimize nighttime urination. Most people can continue their normal activities with some adjustments.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, your doctor may adjust the dose or switch to another medicine. Stopping suddenly can cause a dangerous increase in blood pressure.

📅 Long-Term Use Effects

Long-term use requires regular monitoring of blood pressure, kidney function, and electrolytes. This medicine can cause electrolyte imbalances and kidney impairment if not monitored. It may also increase uric acid levels, potentially worsening gout. Regular follow-up with your doctor is essential to adjust the dose and manage any side effects.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and weight loss can help lower blood pressure and may reduce the need for medication.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, calcium channel blockers, or beta-blockers may be alternatives if this medicine is not suitable.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, consult your doctor before receiving any live vaccines while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue taking your dose at the same local time as usual, but consult your doctor if you need to adjust. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of hypertension not controlled on Telmisartan alone.
He was prescribed this medicine by his cardiologist. After 4 weeks, his blood pressure stabilized at 130/85 mmHg. He experienced mild dizziness initially, which resolved after a week. He was advised to take it in the morning and avoid alcohol.
💡 Lesson: Combination therapy can be effective when monotherapy fails. Initial side effects often subside with continued use.
👤 A 62-year-old woman with hypertension and mild renal impairment.
She started this medicine and was monitored closely with blood tests. Her kidney function remained stable, and her blood pressure improved. She was advised to avoid NSAIDs and stay hydrated.
💡 Lesson: Regular monitoring is crucial for patients with kidney issues. Avoiding NSAIDs helps prevent kidney injury.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1-2 hours, but maximum effect may take 2-4 weeks of regular use.

Q: Can I take this medicine at night?

A: It is usually taken in the morning to avoid nighttime urination. Follow your doctor's advice.

Q: What should I do if I miss a dose?

A: If you remember within 12 hours, take it. Otherwise, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe during pregnancy?

A: No, this medicine is not safe during pregnancy and can harm the fetus. Contact your doctor immediately if you become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my other blood pressure medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for telma-d tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause dangerous increases in blood pressure.
  • Myth: This medicine damages the kidneys.
    Fact: When used appropriately, this medicine can protect the kidneys. However, regular monitoring is necessary.
  • Myth: You can eat anything while taking this medicine.
    Fact: A healthy diet low in salt and rich in fruits and vegetables is important for blood pressure control.

🔄 Alternative Options

Generic Alternatives

  • Telmisartan + Indapamide combination generics

Brand Alternatives

  • Inditel D Capsule SR

📊 Comparison with Similar Medicines

[{"medicine":"Telmisartan + Indapamide","composition":"Telmisartan 40 mg + Indapamide 1.5 mg","release_type":"Sustained-release","usual_dose":"Once daily"},{"medicine":"Telmisartan + Hydrochlorothiazide","composition":"Telmisartan 40 mg + Hydrochlorothiazide 12.5 mg","release_type":"Immediate-release","usual_dose":"Once daily"},{"medicine":"Telmisartan + Amlodipine","composition":"Telmisartan 40 mg + Amlodipine 5 mg","release_type":"Immediate-release","usual_dose":"Once daily"}]

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