telbenina tablet - Benidipine (4mg) + Telmisartan (40mg) medicine

Benitowa Trio Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 UTH Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. This medicine is not recommended during pregnancy as it may harm the fetus. Consult your doctor immediately if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for the treatment of hypertension.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Swelling of face, lips, tongue, or throat
  • Difficulty breathing
  • Chest pain or irregular heartbeat
  • Decreased urine output or swelling in legs
  • Yellowing of skin or eyes
  • Severe abdominal pain or vomiting

If experiencing severe symptoms, call emergency services immediately.

What is telbenina tablet used for?

This medicine is a combination of Benidipine and Telmisartan used to treat high blood pressure. It works by relaxing blood vessels and reducing the workload on the heart. It is taken once daily as prescribed by your doctor.

  • Generic Name: Benidipine (4mg) + Telmisartan (40mg)
  • Manufacturer: UTH Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 telbenina tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। यह बेनिडिपिन और टेल्मिसार्टन का संयोजन है, जो रक्त वाहिकाओं को आराम देकर और हृदय पर दबाव कम करके रक्तचाप को नियंत्रित करती है। यह दवा दिल के दौरे, स्ट्रोक और गुर्दे की समस्याओं के जोखिम को कम करने में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव जैसे सिरदर्द, चक्कर आना, थकान और टखनों में सूजन हो सकते हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको बेहोशी, सांस लेने में कठिनाई, या चेहरे पर सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा की मात्रा न बदलें और न ही बंद करें। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं और रक्तचाप बहुत कम हो सकता है। उठते-बैठते समय धीरे-धीरे करें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। नियमित रूप से रक्तचाप और गुर्दे की जांच कराते रहें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 telbenina tablet Uses & Benefits

  • [{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults when a single medicine is not effective.
  • It helps reduce the risk of heart attack, stroke, and kidney problems.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Hypertension

Also treats: Cardiovascular risk reduction, Chronic kidney disease with proteinuria

📋 Drug Information

Generic Name(s)Benidipine (4mg) + Telmisartan (40mg)
Brand Nametelbenina tablet
ManufacturerUTH Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood pressure control.
2
Monitor your blood pressure regularly at home and keep a record to share with your doctor.
3
Avoid alcohol as it can enhance the blood pressure-lowering effect and cause dizziness.
4
Do not take potassium supplements or salt substitutes without consulting your doctor.
5
Inform your doctor if you experience swelling of ankles, persistent dizziness, or fatigue.
6
Follow a low-salt diet and regular exercise to enhance the effectiveness of this medicine.
7
Do not stop this medicine abruptly; consult your doctor first.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBenidipine is rapidly absorbed after oral administration. Telmisartan is also absorbed orally, with peak plasma concentrations reached within 0.5 to 1.5 hours for benidipine and 0.5 to 1 hour for telmisartan. Food does not significantly affect the absorption of telmisartan, but taking the tablet with food may reduce stomach upset.
DistributionBoth drugs are highly bound to plasma proteins and distribute widely into tissues. Telmisartan has a large volume of distribution. Benidipine is highly lipophilic and accumulates in vascular tissues.
Protein BindingBenidipine is approximately 98% bound to plasma proteins. Telmisartan is more than 99.5% bound to plasma proteins, mainly albumin and alpha-1 acid glycoprotein.
MetabolismBenidipine is metabolized in the liver primarily by CYP3A4 enzymes. Telmisartan is metabolized minimally by conjugation to glucuronide, with no significant CYP450 metabolism.
Half-LifeThe elimination half-life of benidipine is approximately 1-2 hours. Telmisartan has a terminal elimination half-life of about 24 hours.
ExcretionBenidipine is excreted mainly in urine and feces as metabolites. Telmisartan is excreted predominantly in feces via bile, with less than 1% excreted unchanged in urine.
BioavailabilityThe absolute bioavailability of benidipine is about 10% due to first-pass metabolism. Telmisartan has a bioavailability of approximately 42-58%.
Onset of ActionBlood pressure lowering effect begins within 1-2 hours after oral administration. Maximum effect is usually seen within 2-4 weeks of continuous therapy.
Peak Plasma TimePeak plasma concentrations are reached within 0.5-1.5 hours for benidipine and 0.5-1 hour for telmisartan after oral intake.
Duration of ActionThe antihypertensive effect lasts for about 24 hours, allowing once-daily dosing.

How It Works

This medicine combines two active ingredients with complementary actions. Benidipine blocks calcium channels in the smooth muscle of blood vessels, causing them to relax and widen, which lowers blood pressure. Telmisartan blocks angiotensin II receptors, preventing the hormone angiotensin II from constricting blood vessels and stimulating aldosterone release. The combined effect reduces peripheral resistance and lowers blood pressure more effectively than either agent alone.

Mechanism Steps

1
Calcium channel blockade by Benidipine: Benidipine blocks L-type calcium channels in vascular smooth muscle cells, reducing calcium entry and causing relaxation of blood vessels.
2
Vasodilation and reduced peripheral resistance: The relaxation of blood vessels leads to widening of arteries, which decreases peripheral vascular resistance and lowers blood pressure.
3
Angiotensin II receptor blockade by Telmisartan: Telmisartan selectively blocks AT1 receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release.
4
Reduced aldosterone effects: Blocking AT1 receptors decreases aldosterone secretion, leading to reduced sodium and water retention, which further lowers blood pressure.
5
Combined antihypertensive effect: The two mechanisms work together to produce a more pronounced and sustained reduction in blood pressure than either agent alone.

💡 How to Take telbenina tablet

Strength: Benidipine 4 mg + Telmisartan 40 mg immediate-release tablet.

1Take this medicine orally with a glass of water.
2Swallow the tablet whole. Do not crush, chew, or break it.
3Take it at the same time each day, preferably in the morning.
4You may take it with or without food, but taking it with food may reduce stomach upset.
5Do not take more than the prescribed dose.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one tablet once daily, preferably at the same time each day. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo dose adjustment is required for mild to moderate renal impairment. In severe renal impairment or patients on dialysis, use with caution and monitor kidney function. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. In severe hepatic impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is one tablet (Benidipine 4 mg + Telmisartan 40 mg) once daily. Do not exceed this dose unless directed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels and cause excessive blood pressure lowering.
High-potassium foods
Consume in moderation
May increase potassium levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of telbenina tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you. Rise slowly from sitting or lying positions.
Fatigue (Common (1-5%))
Ensure adequate rest. If fatigue interferes with daily activities, consult your doctor.
Peripheral edema (swelling of ankles/feet) (Common (5-10%))
Elevate your legs when sitting. If swelling is severe or accompanied by shortness of breath, seek medical attention.
Flushing (Common (1-5%))
Usually transient. Stay hydrated and avoid excessive heat.

🚨 Serious Side Effects

Severe hypotension (very low blood pressure) (Rare (<0.1%))
Seek immediate medical attention if you experience fainting, severe dizziness, or blurred vision.
Acute kidney injury (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Hyperkalemia (high potassium levels) (Uncommon (0.1-1%))
Regular blood tests are needed. Report muscle weakness, irregular heartbeat, or numbness.
Angioedema (swelling of face, lips, throat) (Rare (<0.1%))
Stop the medicine and seek emergency medical help immediately if you experience swelling of the face, lips, tongue, or difficulty breathing.
Severe allergic reaction (Rare (<0.1%))
Seek emergency care if you develop rash, itching, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Jaundice
Report yellowing of skin or eyes to your doctor immediately.
Rhabdomyolysis
Seek immediate medical attention if you experience muscle pain, tenderness, or dark urine.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Potassium supplements Major
Lithium Major
NSAIDs Major
CYP3A4 inhibitors Major
Diuretics Moderate
Beta-blockers Moderate
Alpha-blockers Moderate
Grapefruit juice Minor
St. John's wort Minor

🚨 Major Interactions

  • Potassium supplements or potassium-sparing diuretics
  • Lithium
  • NSAIDs (e.g., ibuprofen, naproxen)
  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)

⚡ Moderate Interactions

  • Diuretics
  • Beta-blockers
  • Alpha-blockers

🍷 Alcohol Interaction

Alcohol can enhance the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, and increased risk of falls. It is advisable to avoid alcohol or limit intake while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to benidipine, telmisartan, or any component of the formulation","Pregnancy","Severe liver impairment","Biliary obstructive disorders","Concomitant use with aliskiren in patients with diabetes"]

⚠️ Warnings & Precautions

["This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not stop taking this medicine abruptly without consulting your doctor.","Inform your doctor if you have kidney or liver disease, heart failure, or are on a low-salt diet.","Avoid potassium supplements and salt substitutes unless prescribed.","This medicine is not recommended during pregnancy and breastfeeding.","Regular monitoring of blood pressure, kidney function, and electrolytes is required."]

🤱 Lactation Safety

Not established from the available information. It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe hypotension, dizziness, and fainting. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic, including monitoring of vital signs and administration of intravenous fluids if needed.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Avoid alcohol as it can lower your blood pressure further and increase dizziness. Stand up slowly from sitting or lying down to prevent falls. Inform your doctor if you have kidney or liver disease, are pregnant, or planning pregnancy. Do not take potassium supplements or salt substitutes without consulting your doctor. Keep all follow-up appointments for blood pressure and kidney function monitoring.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects and are at higher risk of dizziness and falls. Start with a lower dose and monitor closely.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before surgery. It may need to be temporarily stopped to prevent blood pressure fluctuations during surgery.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. It may cause dry mouth or dizziness, and interactions with local anesthetics are possible.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce blood pressure.
🥗
Follow a low-salt diet rich in fruits and vegetables.
😴
Engage in regular physical activity like walking or swimming.
💧
Limit alcohol and avoid smoking.
🧘
Manage stress through relaxation techniques.
🌞
Get adequate sleep.

🏋️ Exercise Considerations

Moderate exercise is beneficial, but avoid sudden strenuous activities that may cause dizziness. Stay hydrated and rise slowly after exercise.

🥗 Diet Recommendations

Reduce salt intake.
Include potassium-rich foods in moderation.
Avoid processed and high-fat foods.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, especially when starting treatment. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their daily activities with caution.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored appropriately. Regular check-ups of blood pressure, kidney function, and electrolytes are necessary. It helps reduce the risk of cardiovascular events and kidney damage. Do not stop the medicine without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help lower blood pressure and complement medication.

Evidence: Well-established
Other antihypertensive combinations

Your doctor may prescribe alternative combinations if this medicine is not suitable for you.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your healthcare provider about this medicine before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip and carry it in your hand luggage. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of hypertension not controlled on a single medicine.
He was prescribed this medicine once daily. After 4 weeks, his blood pressure stabilized, and he reported feeling more energetic. He experienced mild ankle swelling initially, which improved with leg elevation. He emphasized the importance of taking the medicine at the same time every day.
💡 Lesson: Consistent daily dosing and regular follow-up are key to achieving blood pressure control and preventing complications.
👤 A 62-year-old woman with diabetes and hypertension.
She started this medicine and noticed significant improvement in her blood pressure readings. She was advised to monitor her kidney function regularly. She also adopted a low-salt diet and light exercise, which further helped her condition.
💡 Lesson: Lifestyle modifications along with medication can improve outcomes and reduce the risk of kidney damage in diabetic patients.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1-2 hours, but the full effect may take 2-4 weeks of regular use.

Q: Can I stop taking this medicine if my blood pressure is normal?

A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause a dangerous rise.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for telbenina tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause a dangerous rise in blood pressure.
  • Myth: This medicine can be taken without a prescription.
    Fact: This is a prescription medicine. It should only be taken under a doctor's supervision.
  • Myth: This medicine causes kidney damage.
    Fact: When used appropriately, this medicine can protect the kidneys in hypertensive patients. Regular monitoring is important.

🔄 Alternative Options

Generic Alternatives

  • Benidipine 4 mg + Telmisartan 40 mg tablet (generic)

📊 Comparison with Similar Medicines

[{"medicine":"Benidipine + Telmisartan","class":"Calcium channel blocker + Angiotensin receptor blocker","usual_dose":"Once daily","common_side_effects":"Headache, dizziness, ankle swelling"},{"medicine":"Amlodipine + Telmisartan","class":"Calcium channel blocker + Angiotensin receptor blocker","usual_dose":"Once daily","common_side_effects":"Ankle swelling, headache, dizziness"}]

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