Resteclin 500 Capsule (Tetracycline 500 mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe, watery, or bloody diarrhea that does not improve
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain
- Severe headache with blurred vision or visual disturbances
- Swelling of the face, lips, tongue, or throat, or difficulty breathing
- Chest pain, palpitations, or irregular heartbeat
- Unusual bruising or bleeding
- Decreased urine output or swelling in the legs
- High fever with rash or joint pain
If experiencing severe symptoms, call emergency services immediately.
What is subamycin 500mg capsule used for?
This medicine is a tetracycline antibiotic used to treat a variety of bacterial infections, including acne, chlamydia, and atypical pneumonia. It works by stopping bacteria from making proteins. It should be taken on an empty stomach with water, and avoided in pregnancy and children under 8 years.
- Generic Name: Tetracycline (500mg)
- Manufacturer: Deys Medical
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 subamycin 500mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा टेट्रासाइक्लिन वर्ग की एक एंटीबायोटिक है, जिसका उपयोग विभिन्न प्रकार के बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। इसमें मुँहासे (एक्ने), क्लैमाइडिया, माइकोप्लाज्मा निमोनिया, रिकेट्सियल संक्रमण, ब्रुसेलोसिस, हैजा, लाइम रोग और कुछ मसूड़ों की बीमारियाँ शामिल हैं। यह दवा बैक्टीरिया के प्रोटीन संश्लेषण को रोककर उनकी वृद्धि को रोकती है। इसे खाली पेट, पानी के साथ लेना चाहिए और दूध, दही, चीज़, एंटासिड, आयरन या कैल्शियम सप्लीमेंट के साथ नहीं लेना चाहिए। गर्भवती महिलाओं, स्तनपान कराने वाली माताओं और 8 वर्ष से कम उम्र के बच्चों को यह दवा नहीं दी जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, भूख न लगना और मुँह या जीभ में छाले शामिल हैं। कुछ लोगों को धूप के प्रति संवेदनशीलता, चक्कर आना या सिरदर्द भी हो सकता है। गंभीर दुष्प्रभावों में खूनी दस्त, यकृत की क्षति (पीलिया, गहरे रंग का पेशाब), गंभीर सिरदर्द के साथ दृष्टि में बदलाव, और एलर्जी प्रतिक्रियाएँ जैसे चेहरे या गले में सूजन शामिल हैं। यदि कोई भी गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे एक गिलास पानी के साथ लें और लेने के बाद 30 मिनट तक लेटें नहीं। दूध, दही, चीज़, एंटासिड, आयरन या कैल्शियम सप्लीमेंट के साथ न लें, क्योंकि ये दवा के अवशोषण को कम कर सकते हैं। यदि एंटासिड लेना आवश्यक हो तो इस दवा से 2 घंटे पहले या बाद में लें। गर्भावस्था, स्तनपान और 8 वर्ष से कम उम्र के बच्चों में इस दवा का उपयोग न करें। धूप में बाहर निकलते समय सनस्क्रीन और सुरक्षात्मक कपड़े पहनें। शराब का सेवन न करें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें।
💊 subamycin 500mg capsule Uses & Benefits
[{"condition":"Acne vulgaris","description":"This medicine is used to treat moderate to severe inflammatory acne by reducing the bacteria that contribute to acne and decreasing inflammation in the skin.","evidence":"Well-established"},{"condition":"Chlamydia trachomatis infection","description":"This medicine is an effective treatment for uncomplicated genital chlamydia infection when other first-line options are not suitable.","evidence":"Well-established"},{"condition":"Mycoplasma pneumoniae pneumonia","description":"This medicine is used to treat respiratory tract infections caused by Mycoplasma pneumoniae, a common cause of atypical pneumonia.","evidence":"Well-established"},{"condition":"Rickettsial infections","description":"This medicine is the treatment of choice for Rocky Mountain spotted fever and other rickettsial diseases such as scrub typhus.","evidence":"Well-established"},{"condition":"Brucellosis","description":"This medicine is used in combination with other antibiotics such as rifampin or streptomycin to treat brucellosis, a bacterial infection acquired from animals.","evidence":"Well-established"},{"condition":"Cholera","description":"This medicine is used as an adjunct to fluid replacement to shorten the duration of diarrhea and reduce fluid loss in cholera.","evidence":"Well-established"},{"condition":"Lyme disease","description":"This medicine is an alternative treatment for early Lyme disease in patients who cannot take first-line antibiotics.","evidence":"Well-established"},{"condition":"Periodontitis","description":"This medicine is sometimes used as an adjunct to scaling and root planing in aggressive periodontitis to reduce periodontal pathogens.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Rosacea","description":"Sometimes prescribed off-label for inflammatory rosacea due to its anti-inflammatory and antibacterial effects.","evidence":"Limited"},{"condition":"Malaria prophylaxis","description":"This medicine has been used off-label for malaria prevention in travelers who cannot take standard antimalarials, but resistance is common.","evidence":"Limited"},{"condition":"Sclerosing cholangitis","description":"Rarely used off-label in some liver conditions, but evidence is weak and not recommended routinely.","evidence":"Insufficient"}]
Primary treatment for: Bacterial infections
Also treats: Acne vulgaris, Chlamydia infection, Mycoplasma pneumonia, Rickettsial infections, Brucellosis, Cholera, Lyme disease, Periodontitis
📋 Drug Information
| Generic Name(s) | Tetracycline (500mg) |
| Brand Name | subamycin 500mg capsule |
| Manufacturer | Deys Medical |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Tetracyclines |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F) in a dry place. Keep the capsules in their original container, tightly closed, away from direct sunlight and moisture. Do not refrigerate unless specifically instructed. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture. Check the expiry date on the package before use. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding reversibly to the 30S ribosomal subunit of susceptible bacteria, blocking the attachment of aminoacyl-tRNA to the messenger RNA-ribosome complex. This prevents the addition of new amino acids to the growing peptide chain, thereby inhibiting bacterial protein synthesis. Because protein synthesis is essential for bacterial growth and multiplication, this medicine stops bacteria from reproducing and allows the body's immune system to clear the infection. It is bacteriostatic, meaning it does not directly kill bacteria but inhibits their growth. This medicine is effective against a wide range of gram-positive and gram-negative bacteria, as well as atypical organisms such as Mycoplasma, Chlamydia, Rickettsia, and spirochetes. Resistance can develop through efflux pumps, ribosomal protection proteins, or enzymatic inactivation of the drug.
Mechanism Steps
💡 How to Take subamycin 500mg capsule
Strength: This medicine is available as a 500 mg immediate-release capsule for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 500 mg taken orally every 6 to 12 hours, depending on the type and severity of the infection. For acne, a lower dose such as 500 mg once or twice daily may be used. For severe infections, higher doses may be prescribed. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription exactly and complete the full course. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally contraindicated in children under 8 years of age due to the risk of permanent tooth discoloration and effects on bone growth. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially nausea, diarrhea, and photosensitivity. Renal function should be assessed before and during treatment, and dosage may need adjustment if kidney function is impaired. The dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dosage adjustment is usually necessary. In severe renal impairment (creatinine clearance less than 30 mL/min), the dose should be reduced or the dosing interval extended. The dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | In patients with hepatic impairment, this medicine should be used with caution. Dosage reduction may be necessary, and liver function should be monitored. The dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 2 grams (2000 mg) per day in divided doses for adults. Higher doses should only be used under close medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of subamycin 500mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Antacids | Major | |
| Iron supplements | Major | |
| Calcium supplements | Major | |
| Isotretinoin | Major | |
| Warfarin | Major | |
| Methotrexate | Major | |
| Penicillins | Moderate | |
| Oral contraceptives | Moderate | |
| Digoxin | Moderate | |
| Lithium | Moderate |
🚨 Major Interactions
- Antacids containing aluminum, calcium, or magnesium
- Iron supplements
- Calcium supplements
- Isotretinoin
- Warfarin
- Methotrexate
⚡ Moderate Interactions
- Penicillins
- Oral contraceptives
- Digoxin
- Lithium
- Diuretics
🍷 Alcohol Interaction
Alcohol may worsen stomach upset, dizziness, and nausea caused by this medicine. It is advisable to avoid alcohol while taking this medicine, especially if you have an underlying liver condition.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to tetracyclines","Pregnancy","Breastfeeding","Children under 8 years of age","Severe renal impairment","Severe hepatic impairment","Concurrent use with isotretinoin"]
⚠️ Warnings & Precautions
["Take with a full glass of water and remain upright for 30 minutes to prevent esophageal irritation.","Avoid taking with dairy products, antacids, or iron supplements.","Use sunscreen and protective clothing due to photosensitivity risk.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use in pregnancy or breastfeeding.","Complete the full course as prescribed to prevent resistance.","Report severe diarrhea, which may indicate C. difficile infection.","Monitor for signs of liver injury such as jaundice or dark urine.","Use with caution in patients with renal or hepatic impairment.","May reduce the effectiveness of oral contraceptives; use backup contraception."]
🤱 Lactation Safety
This medicine is excreted in breast milk and may cause dental staining and bone effects in the nursing infant. It is generally not recommended during breastfeeding unless the benefit outweighs the risk. Consult your doctor for alternative options.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, diarrhea, and abdominal pain. There is no specific antidote. Treatment is supportive and symptomatic. If a large amount has been ingested, seek immediate medical attention. Gastric lavage may be considered if ingestion occurred within 1-2 hours. Monitor electrolytes and hydration status.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, with a full glass of water, and do not lie down for at least 30 minutes after swallowing the capsule to prevent irritation of the food pipe. Avoid taking this medicine with milk, yogurt, cheese, antacids, iron supplements, or calcium supplements because these can bind to the medicine and reduce its absorption. If you need an antacid, take it at least two hours before or after this medicine. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding, as it can harm the developing baby's teeth and bones. Children under eight years of age should not take this medicine unless specifically directed by a pediatrician for a serious infection. Use effective sunscreen and protective clothing while taking this medicine because your skin may become more sensitive to sunlight. Avoid alcohol while taking this medicine, as it can worsen stomach upset and dizziness. Do not share this medicine with anyone else, even if they have similar symptoms, and do not save leftover capsules for future use. Complete the entire prescribed course even if you feel better, and contact your doctor if symptoms do not improve within a few days or if they worsen.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function and may be more susceptible to the side effects of this medicine. Dose adjustment may be necessary based on renal function. Monitor for signs of dehydration, dizziness, and photosensitivity. Regular monitoring of kidney and liver function is advised.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy and in women planning to become pregnant. If you are trying to conceive, inform your doctor so that an alternative antibiotic can be prescribed. Use effective contraception while taking this medicine and for at least 7 days after completing the course.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with certain medications used during surgery. Your doctor may advise you to stop the medicine temporarily before surgery. Follow your surgeon's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine may affect the outcome of certain dental treatments and can interact with medications used in dentistry. It may also cause tooth discoloration in children, so it is contraindicated in children under 8 years.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or photosensitivity. Avoid strenuous outdoor exercise during peak sun hours. If you feel dizzy, avoid exercising until the effect wears off. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, nausea, or photosensitivity, which can affect your ability to drive or operate machinery. Avoid driving until you know how it affects you. If your work involves prolonged sun exposure, take extra precautions. Otherwise, most people can continue their normal daily activities while taking this medicine.
🛑 When to Stop This Medicine
Do not stop taking this medicine before completing the full prescribed course, even if you feel better, as this can lead to relapse and antibiotic resistance. If you experience severe side effects such as bloody diarrhea, signs of liver injury, or severe allergic reactions, stop the medicine and seek immediate medical attention. Always consult your doctor before stopping this medicine for any reason.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to antibiotic resistance, fungal overgrowth (such as oral thrush or vaginal yeast infections), and rarely, liver toxicity or blood disorders. Prolonged use may also cause photosensitivity and gastrointestinal disturbances. Regular monitoring of liver and kidney function is recommended if used for more than a few weeks. This medicine should only be used for as long as prescribed by your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another tetracycline antibiotic with better absorption and fewer gastrointestinal side effects.
Evidence: Well-establishedA tetracycline antibiotic often used for acne, with a longer half-life.
Evidence: Well-establishedFor acne, topical clindamycin or erythromycin may be used instead of oral antibiotics.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines such as the typhoid vaccine. Avoid receiving live bacterial vaccines while taking this medicine. Inactivated vaccines are generally safe. Consult your doctor for specific vaccine timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel, as some countries have strict rules about antibiotics. Store the capsules in a cool, dry place away from direct sunlight. If crossing time zones, continue taking the medicine at the same intervals as prescribed; you may need to adjust the timing gradually. Do not pack it in checked luggage; keep it in your carry-on bag. Check customs regulations for your destination regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but it may take several days for full effect. Complete the full course as prescribed.
A: It is best taken on an empty stomach, at least 1 hour before or 2 hours after meals, because food reduces its absorption.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, this medicine is contraindicated during pregnancy as it can harm the developing baby's teeth and bones. Consult your doctor for alternatives.
A: It is advisable to avoid alcohol as it can worsen stomach upset and dizziness.
🤔 Common Patient Concerns
🔄 Substitutes for subamycin 500mg capsule
View AllAlternative brands with exact same active ingredient:
-
terapal 500mg capsuleJagsonpal Pharmaceuticals Ltd ₹9.52 155.9% COSTLIER
-
tetrastar 500mg capsuleCadila Pharmaceuticals Ltd ₹10.74 188.7% COSTLIER
-
getra 500mg capsuleZydus Cadila ₹11.25 202.4% COSTLIER
-
Tetlin 500mg CapsuleInd Swift Laboratories Ltd ₹12.60 238.7% COSTLIER
-
tm 500mg capsulePfizer Ltd ₹13.98 275.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken with milk to reduce stomach upset.
Fact: Milk and dairy products bind to this medicine and reduce its absorption, making it less effective. Take it with water instead. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full prescribed course to ensure the infection is fully treated and to prevent antibiotic resistance. - Myth: This medicine is safe for children and pregnant women.
Fact: This medicine is contraindicated in pregnancy and children under 8 years due to risks of tooth discoloration and bone effects. - Myth: This medicine works for viral infections like the common cold.
Fact: This medicine is an antibiotic and is only effective against bacterial infections, not viruses.
🔄 Alternative Options
Generic Alternatives
- Tetracycline hydrochloride 500 mg capsules
Brand Alternatives
- Resteclin 500 capsule