Augymox 125 Mg/31.25 Mg Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing
- Severe or bloody diarrhoea, or diarrhoea that persists after stopping the medicine
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain
- Widespread rash with fever, blisters, or peeling skin
- Unusual bleeding or bruising, or signs of infection such as fever and chills
- Decreased urine output or swelling in the legs or feet
- Seizures or severe confusion
If experiencing severe symptoms, call emergency services immediately.
What is sporiclav oral suspension used for?
This medicine is an antibiotic combination of amoxycillin and clavulanic acid used to treat bacterial infections of the ear, nose, throat, chest, skin, and urinary tract. It works by killing bacteria and by blocking the enzymes that would otherwise make the bacteria resistant to amoxycillin. It should be taken exactly as prescribed, and the full course should be completed.
- Generic Name: Amoxycillin (125mg) + Clavulanic Acid (31.25mg)
- Manufacturer: Arbro Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sporiclav oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा अमोक्सिसिलिन और क्लैवुलैनिक एसिड का संयोजन है, जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। यह कान, नाक, गले, छाती, त्वचा और मूत्र मार्ग के संक्रमणों में प्रभावी है। यह बैक्टीरिया को मारती है और उन एंजाइमों को रोकती है जो अमोक्सिसिलिन को नष्ट कर सकते हैं। यह दवा वायरल संक्रमण जैसे सर्दी-जुकाम के लिए नहीं है। इसे डॉक्टर के निर्देशानुसार ही लें और पूरा कोर्स पूरा करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट दर्द और त्वचा पर दाने शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। कभी-कभी गंभीर एलर्जी, लीवर की समस्या, या गंभीर दस्त हो सकते हैं। अगर चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई, पीलिया, या खूनी दस्त हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और पूरा कोर्स पूरा करें। बोतल को अच्छी तरह हिलाकर ही दवा निकालें। सही मात्रा मापने के लिए दी गई चम्मच या कप का ही उपयोग करें। दवा को भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। खुराक भूल जाने पर याद आते ही ले लें, लेकिन अगली खुराक का समय नजदीक हो तो छोड़ दें। दोहरी खुराक न लें। शराब न पिएं। दवा को बच्चों से दूर रखें और एक्सपायरी डेट से पहले ही इस्तेमाल करें।
💊 sporiclav oral suspension Uses & Benefits
[{"condition":"Acute otitis media","description":"This medicine is commonly used to treat middle ear infections in children when bacteria are likely to be resistant to plain amoxycillin.","evidence":"Well-established"},{"condition":"Sinusitis","description":"It is used for bacterial sinus infections when symptoms are severe or persistent and a bacterial cause is suspected.","evidence":"Well-established"},{"condition":"Community-acquired pneumonia","description":"This medicine may be prescribed for mild to moderate community-acquired pneumonia when a beta-lactamase-producing organism is suspected.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"It is used for bacterial skin infections such as cellulitis, abscesses, and infected wounds when susceptible bacteria are involved.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"This medicine can be used for urinary tract infections, especially when resistance to plain amoxycillin is a concern.","evidence":"Well-established"},{"condition":"Dental infections","description":"It may be prescribed for dental abscesses and other odontogenic infections caused by susceptible bacteria.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Animal and human bite wounds","description":"Sometimes used for bite wounds because it covers many of the bacteria found in the mouth, though other antibiotics may be preferred.","evidence":"Limited"},{"condition":"Helicobacter pylori eradication","description":"This medicine is not a standard part of most H. pylori regimens, but it has been studied in some combinations.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Otitis media, Sinusitis, Pneumonia, Skin infections, Urinary tract infections, Dental infections
📋 Drug Information
| Generic Name(s) | Amoxycillin (125mg) + Clavulanic Acid (31.25mg) |
| Brand Name | sporiclav oral suspension |
| Manufacturer | Arbro Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature, between 15°C and 30°C. Protect it from direct sunlight and moisture. Do not freeze the suspension. Keep the bottle tightly closed when not in use. After reconstitution, follow the specific storage instructions provided by the pharmacist, as some suspensions need to be refrigerated and used within a certain number of days. Do not use the medicine after the expiry date printed on the pack. |
| Shelf Life | The shelf life of the dry powder before reconstitution is typically 24 months from the date of manufacture, but this can vary. Once reconstituted, the suspension should usually be used within 7 to 14 days if stored as directed. Always check the label for the exact expiry date and follow the pharmacist's instructions. |
| WHO Guideline | The World Health Organization includes amoxycillin-clavulanic acid in its Model List of Essential Medicines for the treatment of various bacterial infections. It is recommended for specific conditions such as pneumonia in children and some other serious infections, but the exact recommendations depend on local resistance patterns and guidelines. |
| ICMR Guideline | The Indian Council of Medical Research has published treatment guidelines for various infections that may include amoxycillin-clavulanic acid. These guidelines emphasise the importance of using antibiotics judiciously and only when a bacterial infection is confirmed or strongly suspected. The choice of antibiotic should be based on local resistance data and the severity of the infection. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines amoxycillin, a beta-lactam antibiotic, with clavulanic acid, a beta-lactamase inhibitor. Amoxycillin binds to penicillin-binding proteins on the bacterial cell wall and blocks the cross-linking of peptidoglycan, which weakens the cell wall and leads to bacterial death. Clavulanic acid has little antibacterial activity on its own, but it binds irreversibly to many beta-lactamase enzymes produced by bacteria, preventing them from destroying amoxycillin. This allows amoxycillin to reach its target and kill bacteria that would otherwise be resistant. The combination is bactericidal against many gram-positive and gram-negative organisms, including some that produce beta-lactamases.
Mechanism Steps
💡 How to Take sporiclav oral suspension
Strength: This medicine is an oral suspension containing 125 mg of amoxycillin and 31.25 mg of clavulanic acid per 5 mL. It is an immediate-release formulation.
Dosage Information
| Adult Dosage | The adult dose of this medicine depends on the type and severity of the infection, the patient's kidney function, and the susceptibility of the bacteria. A common adult dose for many infections is 500 mg of amoxycillin with 125 mg of clavulanic acid taken every 8 hours, but this suspension strength is usually not the preferred form for adults because it requires large volumes. For severe infections, higher doses may be prescribed. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing of this medicine is based on the child's weight and the severity of the infection. The usual dose is calculated as milligrams of amoxycillin per kilogram of body weight per day, divided into two or three doses. This suspension strength is commonly used in children, but the exact dose must be determined by a pediatrician. Do not use this medicine in children without a prescription, and do not adjust the dose based on age alone. Always use the measuring device provided to ensure accuracy. |
| Elderly Dosage | Older adults may be more sensitive to the side effects of this medicine, especially if they have reduced kidney function. The dose may need to be adjusted based on kidney function tests. Elderly patients should be monitored for signs of liver problems, allergic reactions, and severe diarrhoea. It is important to inform the doctor about all other medicines being taken, as interactions are more common in this age group. |
| Renal Impairment | Patients with kidney impairment may need a lower dose or longer dosing intervals. For mild impairment, the usual dose may be acceptable, but for moderate to severe impairment, the dose should be reduced. The exact adjustment depends on the measured creatinine clearance. This medicine should be used with caution in patients with severe kidney disease, and monitoring of kidney function is advised. Always consult a doctor before taking this medicine if you have kidney problems. |
| Hepatic Impairment | Patients with liver problems should use this medicine with caution. The dose may need to be adjusted, and liver function should be monitored. This medicine is not recommended for patients with a history of liver problems caused by amoxycillin-clavulanate. If you have any liver condition, tell your doctor before taking this medicine. |
| Maximum Daily Dose | The maximum daily dose of this medicine depends on the formulation and the patient's kidney function. For the suspension, the maximum daily dose is usually based on the amoxycillin component and should not exceed the recommended limits set by the prescribing doctor. In adults with normal kidney function, the maximum daily dose of amoxycillin is often 4 grams, but this varies by indication. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sporiclav oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Allopurinol | Moderate | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Tetracyclines | Moderate | |
| Chloramphenicol | Moderate | |
| Mycophenolate mofetil | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor |
🚨 Major Interactions
- Warfarin and other oral anticoagulants
- Methotrexate
- Allopurinol
- Probenecid
⚡ Moderate Interactions
- Oral contraceptives
- Tetracyclines
- Chloramphenicol
- Mycophenolate mofetil
🍷 Alcohol Interaction
It is advisable to avoid alcohol while taking this medicine. Alcohol may worsen stomach upset and nausea, and it can increase the risk of liver-related side effects. There is no direct interaction that reduces the effectiveness of the antibiotic, but limiting alcohol is safer for your liver and overall recovery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to amoxycillin, clavulanic acid, or any other penicillin or beta-lactam antibiotic","Previous serious allergic reaction to a beta-lactam antibiotic","History of liver problems caused by this medicine or other amoxycillin-clavulanate combinations","Use in patients with infectious mononucleosis due to high risk of rash","Not for use in viral infections such as the common cold or flu"]
⚠️ Warnings & Precautions
["Before starting this medicine, tell your doctor about all your medical conditions, especially kidney or liver problems.","Inform your doctor if you are allergic to penicillin, cephalosporins, or other antibiotics.","This medicine may reduce the effectiveness of oral contraceptives; use additional contraception during treatment.","Do not use this medicine for longer than prescribed without medical advice, as it can increase the risk of resistance and side effects.","If you develop severe diarrhoea, contact your doctor before taking any anti-diarrhoeal medicine, as some can worsen the condition.","This medicine may cause dizziness in some people; avoid driving or operating machinery until you know how it affects you.","Keep this medicine out of reach of children and store it as directed on the label."]
🤱 Lactation Safety
Amoxycillin and clavulanic acid pass into breast milk in small amounts. This medicine is usually considered compatible with breastfeeding, but it may cause diarrhoea or thrush in the nursing infant. If you notice these symptoms in your baby, consult your doctor. Always inform your doctor if you are breastfeeding before taking this medicine.
💊 Overdose Management
If you or someone else takes too much of this medicine, seek medical attention immediately. Overdose may cause stomach pain, vomiting, diarrhoea, and fluid and electrolyte imbalance. In severe cases, it can lead to kidney problems or seizures. Treatment is supportive and may include activated charcoal if the overdose is recent, as well as measures to maintain hydration and electrolyte balance. Do not try to vomit unless instructed by a healthcare professional. Take the medicine bottle or packaging with you to the hospital so the medical team knows exactly what was taken.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one. If you are unsure what to do, contact your doctor or pharmacist for advice. Try to take the medicine at the same times each day to help you remember.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor, and complete the full course even if you start feeling better after a few days. Shake the bottle well before each dose to make sure the medicine is evenly mixed. Use a proper measuring device such as the spoon or cup provided, not a household spoon, to get the correct amount. This medicine can be taken with or without food, but taking it with a meal may reduce stomach upset. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. Do not share this medicine with anyone else, even if they have similar symptoms, because it may not be the right treatment for them. Tell your doctor if you have kidney problems, liver problems, or a history of allergies, especially to antibiotics. Avoid alcohol while taking this medicine, as it may worsen stomach upset and liver-related side effects. If you develop a rash, swelling, or difficulty breathing, stop the medicine and seek medical help immediately. Store the suspension as directed on the label, and do not use it after the expiry date. Keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more prone to side effects such as diarrhoea, dizziness, and liver problems. Kidney function tends to decline with age, so dose adjustment may be necessary. Elderly patients should be monitored for signs of allergic reactions and severe diarrhoea. It is important to review all other medicines being taken to avoid interactions. Staying hydrated is especially important in this age group.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. This medicine is generally considered safe in pregnancy when prescribed for a bacterial infection, but it should only be used when clearly needed. If you become pregnant while taking this medicine, inform your doctor immediately. Do not start or stop any medicine without medical advice.
🏥 Post-Surgery Considerations
If you have recently had surgery, tell your surgeon and doctor before taking this medicine. It may be used to treat or prevent surgical site infections, but the dose and duration will be determined by your medical team. Inform them of any allergies and other medicines you are taking. Monitor for signs of infection at the surgical site, such as redness, swelling, or discharge.
🦷 Dental Procedures
This medicine may be prescribed before or after dental procedures to treat or prevent infection. Inform your dentist if you are taking this medicine or have any allergies to antibiotics. It is important to complete the prescribed course. If you experience any side effects, contact your dentist or doctor. Good oral hygiene is also important during treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you can continue with light to moderate exercise if you feel well. However, if you have a fever, severe pain, or feel very tired, it is better to rest and avoid strenuous activities. Some people may experience dizziness or stomach upset, so avoid heavy lifting or intense workouts until you know how the medicine affects you. Always listen to your body and consult your doctor before resuming intense exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, nausea, or diarrhoea in some people, which can affect your ability to drive or operate machinery. If you experience these side effects, avoid driving or operating heavy machinery until you feel better. Most people can continue their normal work routine, but if you have a fever or feel unwell, take rest. Inform your employer if you need to take time off. Always follow your doctor's advice about returning to work.
🛑 When to Stop This Medicine
You should stop taking this medicine only after completing the full course prescribed by your doctor, even if you feel better. If you experience a serious side effect such as a severe allergic reaction, severe diarrhoea, or signs of liver problems, stop the medicine and seek medical help immediately. Do not stop the medicine early on your own, as this can allow the infection to return and may lead to antibiotic resistance. If you have any concerns, talk to your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of antibiotic resistance, fungal infections, and rarely liver problems. It should only be used for the prescribed duration. If you need repeated courses, your doctor may investigate the underlying cause of your infections. Prolonged use may also affect the normal bacteria in your gut, leading to diarrhoea or other digestive issues. Regular monitoring of liver and kidney function may be needed if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be used if the bacteria are not expected to produce beta-lactamases.
Evidence: Well-establishedAlternative antibiotics for patients allergic to penicillin, depending on the type of infection.
Evidence: Well-establishedMay be used for respiratory infections when penicillin cannot be used.
Evidence: Well-establishedFor viral infections, rest, fluids, and fever reducers are the mainstay.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines. However, if you are scheduled to receive a live bacterial vaccine such as the typhoid vaccine, antibiotics may reduce its effectiveness. Inform your doctor if you are due for any vaccinations while taking this medicine. In general, it is safe to receive inactivated vaccines while on antibiotics.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not freeze the suspension
✅ DO
Keep in original container with the cap tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Follow the pharmacist's instructions for storage after reconstitution
❌ DON'T
Do not use after the expiry date or beyond the recommended period after mixing
✈️ Traveling with This Medicine
When travelling with this medicine, carry it in its original packaging with the prescription label clearly visible. Keep a copy of your prescription with you in case customs or security officials ask for it. If you are travelling across time zones, try to maintain the dosing schedule as close to every 8 or 12 hours as possible, but do not double up on doses. Store the suspension as directed, and if it needs refrigeration, use a cool bag or ask your hotel for a refrigerator. Always check the expiry date before use. If you are flying, keep the medicine in your hand luggage to avoid temperature extremes in the checked baggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 72 hours after starting this medicine, but it is important to complete the full course as prescribed. If your symptoms do not improve or worsen, contact your doctor.
A: Yes, this medicine can be taken with or without food. Taking it with a meal may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.
A: Yes, this medicine is commonly used in children, but the dose must be calculated based on the child's weight and prescribed by a pediatrician. Do not give it to a child without a prescription.
A: It is best to avoid alcohol while taking this medicine, as it may worsen stomach upset and increase the risk of liver-related side effects.
A: Store the dry powder at room temperature. After mixing, follow the pharmacist's instructions, which may include refrigeration and using it within a certain number of days. Keep it out of reach of children.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine is an antibiotic and only works against bacteria. The common cold is caused by viruses, so this medicine will not help. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You should complete the full course as prescribed, even if you feel better, to ensure all bacteria are killed and to prevent resistance. - Myth: This medicine is safe to take without a prescription.
Fact: This is a prescription antibiotic. Taking it without medical advice can lead to incorrect treatment, side effects, and antibiotic resistance. - Myth: This medicine can be shared with family members who have similar symptoms.
Fact: Never share antibiotics. The medicine may not be appropriate for another person's condition and can cause harm.
🔄 Alternative Options
Generic Alternatives
- Amoxycillin and clavulanic acid oral suspension 125 mg/31.25 mg per 5 mL
Brand Alternatives
- Augymox 125 mg/31.25 mg suspension