Sodium Chloride (0.49% w/v) + Sodium Lactate (0.39% w/v) + Potassium Chloride (0.075% w/v) + Calcium Chloride (0.048% w/v) (Medical Monograph)

Overview

A balanced, multi-electrolyte intravenous solution designed to mimic the electrolyte composition of plasma. It is a sterile, non-pyrogenic, isotonic solution used for fluid and electrolyte replacement. The sodium lactate component is metabolized to bicarbonate, providing a mild alkalinizing effect, making it suitable for correcting mild metabolic acidosis associated with dehydration.

This solution restores intravascular volume, corrects electrolyte imbalances, and provides a substrate for bicarbonate generation. Sodium and chloride maintain extracellular fluid volume and osmotic pressure. Potassium is the principal intracellular cation. Calcium is essential for neuromuscular function, cardiac contractility, and blood coagulation. Sodium lactate is converted in the liver to bicarbonate, helping to correct mild acidosis.