rexizole-b lotion - Beclometasone (0.025% w/v) + Clotrimazole (1% w/v) medicine

Beclocid Lotion: Complete Medicine Guide

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🏭 Dermarex HealthCare India Pvt. Ltd. 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, or throat, or difficulty breathing.
  • Severe burning, blistering, or peeling of the skin at the application site.
  • Signs of a secondary infection, such as increased redness, warmth, swelling, or pus.
  • Symptoms that worsen or do not improve after 2 weeks of use.
  • New rash or allergic reaction spreading beyond the treated area.
  • Fatigue, weakness, weight loss, or low blood pressure, which may indicate adrenal suppression.

If experiencing severe symptoms, call emergency services immediately.

What is rexizole-b lotion used for?

This medicine is a topical lotion containing beclometasone 0.025% w/v and clotrimazole 1% w/v. It is used to treat inflamed fungal skin infections by reducing inflammation and killing fungi. Apply a thin layer to the affected area as directed by your doctor.

  • Generic Name: Beclometasone (0.025% w/v) + Clotrimazole (1% w/v)
  • Manufacturer: Dermarex HealthCare India Pvt. Ltd.
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 rexizole-b lotion के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल लोशन है जिसमें बेक्लोमेटासोन 0.025% w/v और क्लोट्रिमाज़ोल 1% w/v शामिल हैं। इसका उपयोग त्वचा के उन फंगल संक्रमणों के इलाज के लिए किया जाता है जिनमें सूजन, लालिमा और खुजली भी होती है। बेक्लोमेटासोन सूजन और खुजली को कम करता है, जबकि क्लोट्रिमाज़ोल फंगस को मारता है। इसे प्रभावित त्वचा पर पतली परत में लगाएं। आंखों, मुंह और अन्य श्लेष्मा झिल्ली पर न लगाएं।

साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, लालिमा या सूखापन शामिल हैं। ये आमतौर पर अस्थायी होते हैं। दुर्लभ मामलों में त्वचा का पतला होना, खिंचाव के निशान, या गंभीर एलर्जी प्रतिक्रिया हो सकती है। यदि आपको चेहरे, होंठ या गले में सूजन, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को केवल प्रभावित त्वचा पर लगाएं। आंखों, मुंह और अन्य श्लेष्मा झिल्ली से बचें। लगाने से पहले और बाद में हाथ धोएं। बिना डॉक्टर की सलाह के इसे चेहरे, जांघों या बगलों पर न लगाएं। निर्धारित अवधि से अधिक समय तक उपयोग न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 rexizole-b lotion Uses & Benefits

[{"condition":"Inflamed fungal skin infections","description":"Used to treat fungal infections of the skin that are accompanied by inflammation, redness, and itching, such as tinea corporis with eczematous changes.","evidence":"Well-established"},{"condition":"Athlete's foot with inflammation","description":"Helps relieve itching, burning, and redness associated with fungal infection of the feet while treating the underlying fungus.","evidence":"Well-established"},{"condition":"Jock itch with inflammation","description":"Treats fungal infection in the groin area and reduces associated inflammation and discomfort.","evidence":"Well-established"},{"condition":"Ringworm with eczematous reaction","description":"Provides relief from inflamed, itchy ringworm lesions while eradicating the fungal cause.","evidence":"Well-established"},{"condition":"Candidal skin infections with inflammation","description":"Used for skin candidiasis when inflammation is a prominent feature.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Seborrheic dermatitis with suspected fungal component","description":"Sometimes used when both inflammation and Malassezia yeast are thought to contribute, though not a standard first-line treatment.","evidence":"Limited"},{"condition":"Eczema with secondary fungal infection","description":"May be used when eczema lesions become secondarily infected with fungi, but requires accurate diagnosis.","evidence":"Limited"}]

Primary treatment for: Inflamed fungal skin infections

Also treats: Athlete's foot with inflammation, Jock itch with inflammation, Ringworm with eczematous reaction, Candidal skin infections with inflammation

📋 Drug Information

Generic Name(s)Beclometasone (0.025% w/v) + Clotrimazole (1% w/v)
Brand Namerexizole-b lotion
ManufacturerDermarex HealthCare India Pvt. Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from direct sunlight and moisture. Keep the container tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply this medicine exactly as prescribed and for the full duration, even if symptoms improve early.
2
Do not use this lotion on the face, groin, or underarms unless specifically instructed by your doctor.
3
Avoid covering the treated area with airtight dressings unless directed, as this can increase absorption and side effects.
4
If you are using other topical products on the same area, consult your doctor about the correct order and timing of application.
5
Monitor for signs of skin thinning, such as shiny or easily bruised skin, and report them to your doctor.
6
Keep the affected area clean and dry, and avoid sharing towels or clothing to prevent spreading the infection.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Itchy, red, scaly skin patches
This medicine is commonly prescribed for inflamed fungal skin infections.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Joint pain
This medicine is not for joint pain.
Not Primary
Burning sensation in feet
May be used for athlete's foot with inflammation.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBeclometasone and clotrimazole are absorbed through intact skin to a limited extent. Absorption can increase if the skin is broken, inflamed, or if the lotion is applied over a large area or under occlusive dressings. Systemic absorption of beclometasone may lead to adrenal suppression if used extensively.
DistributionAfter absorption, beclometasone is distributed throughout the body, with a high degree of protein binding. Clotrimazole distributes into tissues, but systemic distribution is minimal after topical application.
Protein BindingBeclometasone is approximately 87-94% bound to plasma proteins. Clotrimazole is highly protein-bound, but exact values are not well established for topical use.
MetabolismBeclometasone is metabolized in the liver, primarily by cytochrome P450 enzymes, to inactive metabolites. Clotrimazole is metabolized in the liver to inactive metabolites.
Half-LifeThe elimination half-life of beclometasone is approximately 15 hours. The elimination half-life of clotrimazole is not well established after topical application.
ExcretionBeclometasone and its metabolites are excreted mainly in the urine and feces. Clotrimazole metabolites are excreted primarily in the feces.
BioavailabilitySystemic bioavailability after topical application is low but can increase with damaged skin, large application areas, or occlusive dressings.
Onset of ActionSymptomatic relief from itching and inflammation may begin within a few hours to days of application. Antifungal effects require several days to become noticeable.
Peak Plasma TimeNot established from the available information for topical application.
Duration of ActionThe anti-inflammatory effect lasts for several hours after application. The antifungal effect persists as long as the medicine is present in the skin.

How It Works

This medicine combines a corticosteroid and an antifungal agent. Beclometasone binds to glucocorticoid receptors inside skin cells, leading to reduced production of inflammatory substances such as prostaglandins and leukotrienes. This decreases redness, swelling, itching, and heat in the applied area. Clotrimazole works by interfering with the synthesis of ergosterol, a vital component of fungal cell membranes. Without ergosterol, the fungal cell membrane becomes leaky and the fungus cannot survive. Together, these actions reduce inflammation and eliminate the fungal infection.

Mechanism Steps

1
Beclometasone binds to glucocorticoid receptors: Beclometasone enters skin cells and binds to cytoplasmic glucocorticoid receptors, forming a complex that moves into the nucleus.
2
Reduction of inflammatory mediators: The receptor complex alters gene transcription, reducing the production of inflammatory cytokines, prostaglandins, and leukotrienes, which decreases redness, swelling, and itching.
3
Clotrimazole inhibits ergosterol synthesis: Clotrimazole blocks the fungal enzyme 14α-demethylase, preventing the conversion of lanosterol to ergosterol, a key component of the fungal cell membrane.
4
Fungal cell membrane damage: Without ergosterol, the fungal cell membrane becomes permeable, leading to leakage of cellular contents and death of the fungus.
5
Combined clinical effect: The anti-inflammatory action provides rapid relief of symptoms, while the antifungal action eradicates the infection, leading to resolution of the skin condition.

💡 How to Take rexizole-b lotion

Strength: Lotion containing beclometasone 0.025% w/v and clotrimazole 1% w/v.

1Wash your hands thoroughly before and after applying the lotion.
2Clean and dry the affected skin area gently.
3Shake the bottle well before use.
4Apply a thin layer of the lotion to the affected area and gently rub it in.
5Do not cover the area with a bandage or dressing unless instructed by your doctor.
6Avoid contact with eyes, mouth, and other mucous membranes.
7Use the medicine exactly as prescribed for the full duration.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected skin area once or twice daily, or as directed by your doctor. The frequency and duration of treatment depend on the condition being treated and your response to therapy. Do not use for longer than prescribed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to the side effects of topical corticosteroids, such as skin thinning. Use with caution and for the shortest duration necessary. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo dosage adjustment is typically required for topical use. However, caution is advised in patients with severe kidney disease. Consult your doctor.
Hepatic ImpairmentNo dosage adjustment is typically required for topical use. However, caution is advised in patients with severe liver disease. Consult your doctor.
Maximum Daily DoseThe maximum daily dose depends on the size of the affected area and the prescribed frequency. Do not exceed the dose recommended by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of rexizole-b lotion

✅ Common Side Effects

Application site burning (Common (1-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Application site itching (Common (1-10%))
May be due to the medicine or the underlying condition. Consult your doctor if it worsens.
Application site redness (Common (1-10%))
Usually temporary. If it spreads or becomes painful, seek medical advice.
Skin dryness (Common (1-10%))
Use a gentle moisturizer if needed. Consult your doctor if it persists.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, throat, or difficulty breathing.
Skin thinning (atrophy) (Uncommon (0.1-1%))
Consult your doctor if you notice thinning, shiny skin, or stretch marks. Prolonged use should be avoided.
Adrenal suppression (Rare (<0.1%))
Seek medical advice if you experience fatigue, weakness, weight loss, or low blood pressure, especially after prolonged use over large areas.
Secondary infection (Uncommon (0.1-1%))
Consult your doctor if the treated area becomes more red, swollen, or painful, or if new lesions appear.

⚠️ Rare Side Effects

Hyperglycemia
Monitor blood sugar if you have diabetes. Consult your doctor if you notice increased thirst or urination.
Glaucoma or increased intraocular pressure
Avoid application near the eyes. Seek medical advice if you experience eye pain or vision changes.
Contact dermatitis
Discontinue use and consult your doctor if you develop a new rash or worsening irritation.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other topical corticosteroids Major
CYP3A4 inhibitors Major
Other topical antifungals Moderate
Immunosuppressants Moderate
Topical moisturizers Minor

🚨 Major Interactions

  • Other topical corticosteroids
  • CYP3A4 inhibitors (e.g., ritonavir, ketoconazole)

⚡ Moderate Interactions

  • Other topical antifungals
  • Immunosuppressants

🍷 Alcohol Interaction

No known interaction between this topical medicine and alcohol. However, alcohol may worsen certain skin conditions or increase inflammation, so moderation is advised.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to beclometasone, clotrimazole, or any component of the lotion.","Untreated bacterial, viral, or parasitic skin infections.","Acne, rosacea, or perioral dermatitis.","Application on open wounds or broken skin.","Use in the eye or on mucous membranes."]

⚠️ Warnings & Precautions

["For external use only. Do not swallow.","Avoid contact with eyes, mouth, and other mucous membranes.","Do not use on the face, groin, or underarms unless directed by a doctor.","Do not cover with airtight dressings unless instructed.","Prolonged use can cause skin thinning and systemic effects.","Consult a doctor if symptoms persist or worsen after 2 weeks of use.","Keep out of reach of children.","Do not use for diaper rash unless directed by a doctor."]

🤱 Lactation Safety

It is not known whether beclometasone or clotrimazole pass into breast milk after topical application. However, systemic absorption is low. To be safe, avoid applying to the breast area and consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose with this topical medicine is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, and signs of corticosteroid excess. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Apply this medicine only to the affected skin area and avoid contact with eyes, mouth, and other mucous membranes. Wash your hands thoroughly before and after application unless your hands are the treated area. Do not cover the treated area with airtight dressings unless instructed by your doctor. Do not use this medicine for longer than prescribed, as prolonged use can cause skin thinning and other side effects. Avoid using it on the face, groin, or underarms unless specifically directed by your doctor, as these areas are more prone to side effects. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to the side effects of topical corticosteroids, such as skin thinning. Use the smallest effective amount for the shortest duration necessary. Monitor for signs of systemic absorption if used over large areas.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Topical corticosteroids and clotrimazole are generally considered low risk, but individual assessment is recommended.

🏥 Post-Surgery Considerations

Consult your doctor before applying this medicine to surgical wounds or nearby areas. Do not apply to open wounds or broken skin unless directed.

🦷 Dental Procedures

No specific considerations for dental procedures. However, inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing towels, clothing, or footwear to prevent spreading the infection.
😴
Wear loose, breathable clothing made of natural fibers.
💧
Avoid scratching the affected area to prevent worsening and secondary infection.
🧘
Maintain good personal hygiene and wash hands frequently.
🌞
Manage stress and get adequate sleep to support immune function.

🏋️ Exercise Considerations

You can continue exercising, but avoid activities that cause excessive sweating or friction on the affected area. Shower immediately after exercise and dry the area thoroughly. Avoid sharing gym equipment or mats until the infection clears.

🥗 Diet Recommendations

Include foods rich in probiotics, such as yogurt, to support healthy skin flora.
Eat a balanced diet rich in fruits and vegetables to support immune function.
Limit sugary and processed foods, which may promote fungal growth.
Stay well hydrated to maintain skin health.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any dizziness or allergic reaction, avoid these activities until you feel better. You can continue your normal daily activities, but keep the treated area clean and dry.

🛑 When to Stop This Medicine

Stop using this medicine and consult your doctor if your symptoms worsen, if you develop a new rash, or if you experience any severe side effects. Do not stop abruptly if you have been using it for a long time without consulting your doctor, as this may cause a flare-up. Complete the prescribed course unless told otherwise.

📅 Long-Term Use Effects

Prolonged use of this medicine, especially over large areas or under occlusive dressings, can lead to skin thinning, stretch marks, and systemic absorption of the corticosteroid. Systemic effects may include adrenal suppression, high blood sugar, and Cushing's syndrome. Use the smallest effective amount for the shortest duration necessary. Regular monitoring by your doctor is advised if long-term use is required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical antifungal alone

If inflammation is mild, a plain antifungal cream may be sufficient.

Evidence: Well-established
Oral antifungal therapy

For extensive or resistant fungal infections, oral antifungals may be prescribed by a doctor.

Evidence: Well-established
Good hygiene practices

Keeping skin clean and dry helps prevent fungal infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction between this topical medicine and vaccines. However, if you are immunocompromised, consult your doctor before receiving live vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C).

❌ DON'T

Do not refrigerate unless specified.

✅ DO

Keep in the original container with the cap tightly closed.

❌ DON'T

Do not transfer to unmarked containers.

✅ DO

Keep away from direct sunlight and moisture.

❌ DON'T

Do not store in the bathroom cabinet.

✅ DO

Keep out of reach of children.

❌ DON'T

Do not use after the expiry date.

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, continue your regular application schedule as prescribed. Do not leave it in a hot car or checked luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with itchy, red, and scaly patches in his groin area.
He was diagnosed with jock itch with significant inflammation. He was prescribed this medicine to apply twice daily. After 3 days, the itching and redness reduced noticeably. He completed the full 2-week course as directed and the infection cleared completely. He learned to keep the area dry and avoid sharing towels.
💡 Lesson: Using the medicine as prescribed and completing the full course helps resolve both inflammation and fungal infection, preventing recurrence.
👤 A 50-year-old woman with athlete's foot that had become inflamed and painful.
She had tried over-the-counter antifungal creams without relief. Her doctor prescribed this medicine. She applied it once daily for 4 weeks. The inflammation subsided within a week, and the fungal infection resolved gradually. She was advised to wear breathable footwear and dry her feet thoroughly.
💡 Lesson: Combination therapy can be effective when inflammation complicates a fungal infection, but proper foot hygiene is essential for prevention.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may notice reduced itching and redness within a few days. The fungal infection may take 1-2 weeks to clear completely. Complete the full course as prescribed.

Q: Can I use this medicine on my face?

A: Do not use on the face unless specifically instructed by your doctor, as it can cause skin thinning and other side effects.

Q: Is it safe during pregnancy?

A: Consult your doctor before using this medicine during pregnancy. Topical corticosteroids and clotrimazole are generally considered low risk when used as directed, but individual assessment is needed.

Q: What should I do if I miss a dose?

A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.

Q: Can I use this medicine for a bacterial infection?

A: No, this medicine is for fungal infections with inflammation. Using it for bacterial infections can worsen the condition. Consult your doctor for proper diagnosis.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine on my face?
  • How long can I use this medicine safely?
  • What if I forget to apply a dose?
  • Can I use this medicine if I am pregnant?
  • Does this medicine interact with other skin products?
  • Can I stop using it once symptoms improve?

🔄 Substitutes for rexizole-b lotion

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any skin rash.
    Fact: It is only effective for fungal infections with inflammation. Using it for other rashes can worsen the condition.
  • Myth: More frequent application means faster healing.
    Fact: Applying more than prescribed can increase side effects without speeding up recovery.
  • Myth: It is safe to use on the face for long periods.
    Fact: Prolonged use on the face can cause skin thinning, acne, and other side effects. Use only as directed.
  • Myth: Once symptoms improve, you can stop using it.
    Fact: You should complete the full course as prescribed to prevent the infection from returning.

🔄 Alternative Options

Generic Alternatives

  • Beclometasone + Clotrimazole lotion (generic)

Brand Alternatives

  • Beclocid lotion

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Beclometasone 0.025% + Clotrimazole 1%","form":"Lotion","primary_use":"Inflamed fungal skin infections"},{"medicine":"Clotrimazole cream","active_ingredients":"Clotrimazole 1%","form":"Cream","primary_use":"Fungal skin infections without significant inflammation"},{"medicine":"Beclometasone cream","active_ingredients":"Beclometasone 0.025%","form":"Cream","primary_use":"Inflammatory skin conditions without fungal infection"},{"medicine":"Hydrocortisone + Clotrimazole cream","active_ingredients":"Hydrocortisone 1% + Clotrimazole 1%","form":"Cream","primary_use":"Mild inflamed fungal skin infections"}]

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