Quadriderm Af Cream: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
- Signs of skin atrophy (thinning skin, stretch marks, easy bruising)
- New or worsening infection
- Severe burning, blistering, or peeling at the application site
- Symptoms of adrenal suppression (fatigue, weakness, weight loss)
- No improvement after 2 weeks of use
If experiencing severe symptoms, call emergency services immediately.
What is quadriderm af cream used for?
This medicine is a topical cream containing betamethasone (a steroid) and clotrimazole (an antifungal). It is used to treat inflamed fungal skin infections like ringworm and jock itch. Apply a thin layer to the affected area twice daily as prescribed.
- Generic Name: Betamethasone (0.64mg) + Clotrimazole (10mg)
- Manufacturer: Fulford India Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 quadriderm af cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें बीटामेथासोन (एक स्टेरॉयड) और क्लोट्रिमाज़ोल (एक एंटीफंगल) शामिल हैं। इसका उपयोग फंगल संक्रमण के साथ सूजन, खुजली और लालिमा वाली त्वचा की समस्याओं जैसे दाद, जॉक इच और एथलीट फुट के इलाज के लिए किया जाता है। यह क्रीम फंगस को मारती है और साथ ही सूजन और खुजली को कम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में लगाने की जगह पर हल्की जलन, खुजली, लालिमा या सूखापन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें त्वचा का पतला होना, खिंचाव के निशान, या एलर्जी की प्रतिक्रिया जैसे चेहरे, होंठ या गले में सूजन हो सकती है। यदि आपको कोई गंभीर दुष्प्रभाव दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस क्रीम को केवल त्वचा पर और डॉक्टर के निर्देशानुसार ही लगाएं। आंखों, मुंह और नाक के संपर्क में न आने दें। बिना डॉक्टर की सलाह के इसे लंबे समय तक या बड़े क्षेत्र पर न लगाएं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। बच्चों में उपयोग से पहले बाल रोग विशेषज्ञ से सलाह लें।
💊 quadriderm af cream Uses & Benefits
[{"condition":"Tinea corporis (ringworm of the body)","description":"This medicine is used to treat ringworm infections of the body that are accompanied by inflammation, reducing both the fungal infection and the associated redness and itching.","evidence":"Well-established"},{"condition":"Tinea cruris (jock itch)","description":"This medicine is effective for inflamed jock itch, providing relief from itching and inflammation while eradicating the fungus.","evidence":"Well-established"},{"condition":"Tinea pedis (athlete's foot)","description":"This medicine is used for inflamed athlete's foot, helping to clear the fungal infection and reduce symptoms such as itching, burning, and scaling.","evidence":"Well-established"},{"condition":"Cutaneous candidiasis","description":"This medicine is used for skin infections caused by Candida species that are associated with inflammation, such as diaper rash or intertrigo.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Seborrheic dermatitis with suspected fungal component","description":"Sometimes prescribed off-label when a fungal element is suspected, but this is not a standard approved use.","evidence":"Limited"}]
Primary treatment for: Fungal skin infections with inflammation
Also treats: Tinea corporis, Tinea cruris, Tinea pedis, Cutaneous candidiasis
📋 Drug Information
| Generic Name(s) | Betamethasone (0.64mg) + Clotrimazole (10mg) |
| Brand Name | quadriderm af cream |
| Manufacturer | Fulford India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines a corticosteroid and an antifungal agent. Betamethasone is a synthetic corticosteroid that binds to glucocorticoid receptors in the cytoplasm, leading to suppression of inflammatory mediators such as prostaglandins and leukotrienes. This reduces redness, swelling, itching, and pain. Clotrimazole is an imidazole antifungal that inhibits the synthesis of ergosterol, a vital component of fungal cell membranes. This leads to increased permeability and leakage of cellular contents, ultimately causing fungal cell death. Together, they address both the inflammatory symptoms and the underlying fungal infection.
Mechanism Steps
💡 How to Take quadriderm af cream
Strength: Cream containing betamethasone 0.64 mg and clotrimazole 10 mg per gram.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected area and surrounding skin twice daily, or as directed by your doctor. The duration of treatment depends on the type and severity of the infection, but typically should not exceed 2-4 weeks. Dose must be individualized by a qualified clinician based on indication, age, and response to treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more susceptible to the effects of corticosteroids. Use with caution and for the shortest duration possible. |
| Renal Impairment | No dosage adjustment is required for renal impairment when used topically, as systemic absorption is minimal. |
| Hepatic Impairment | No specific dosage adjustment is required for hepatic impairment when used topically, but use with caution due to potential systemic absorption. |
| Maximum Daily Dose | Not established from the available information. Use only as prescribed by your doctor. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of quadriderm af cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole (oral) | Major | |
| Ritonavir | Major | |
| Other topical corticosteroids | Major | |
| Other topical antifungals | Moderate |
🚨 Major Interactions
- Other topical corticosteroids
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
⚡ Moderate Interactions
- Other topical antifungals
🍷 Alcohol Interaction
No known interaction between this medicine and alcohol when used topically. However, alcohol consumption may affect underlying skin conditions and should be moderated.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to betamethasone, clotrimazole, or any component of the formulation.","Untreated bacterial or viral skin infections (e.g., herpes simplex, vaccinia, varicella).","Use on the face, groin, or axillae unless directed by a doctor.","Use in children under 2 years of age unless prescribed by a pediatrician."]
⚠️ Warnings & Precautions
["For external use only. Avoid contact with eyes.","Do not use on large areas of the body or for prolonged periods without medical supervision.","Do not use under occlusive dressings unless instructed.","If irritation or sensitization occurs, discontinue use and consult a doctor.","Use with caution in patients with impaired liver function or diabetes.","Do not use for conditions other than those prescribed."]
🤱 Lactation Safety
It is not known whether betamethasone and clotrimazole are excreted in breast milk after topical application. However, systemic absorption is minimal. To be safe, avoid applying the cream to the breast area and consult your doctor before use while breastfeeding.
💊 Overdose Management
Overdose with topical application is unlikely. If accidental ingestion occurs, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, and signs of corticosteroid excess. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Use this medicine only on the skin and only as prescribed by your doctor. Wash your hands thoroughly before and after applying the cream, unless your hands are the treated area. Avoid contact with the eyes, mouth, nose, and other mucous membranes. Do not cover the treated area with bandages or dressings unless instructed by your doctor, as this can increase absorption and side effects. Do not use this medicine for longer than the prescribed duration. If your condition does not improve within the expected time, or if it worsens, consult your doctor. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine on children unless specifically prescribed by a pediatrician. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the effects of corticosteroids. Use with caution and for the shortest duration possible.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Topical use is generally considered safe, but use only if clearly needed.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine on surgical wounds or nearby areas, as it may affect wound healing.
🦷 Dental Procedures
No specific considerations for dental procedures, as this medicine is for topical skin use.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions, but avoid activities that cause excessive sweating or friction on the treated area until the infection clears.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience any dizziness or allergic reaction, avoid these activities.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if your symptoms worsen, if you experience severe irritation, or if you have completed the prescribed course. Do not stop early without consulting your doctor, as the infection may return.
📅 Long-Term Use Effects
Prolonged use or use over large areas can lead to skin atrophy, stretch marks, and systemic absorption of betamethasone, which may cause adrenal suppression. Use for the shortest duration necessary and under medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For fungal infections without significant inflammation.
Evidence: Well-establishedFor severe or widespread infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, if you are scheduled for vaccination, inform your doctor about this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue applying as prescribed; no time adjustment is needed for topical use. Declare it at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice improvement in itching and redness within a few days. The fungal infection typically clears within 2-4 weeks of regular use.
A: No, unless specifically instructed by your doctor. Using it on the face can cause skin thinning and other side effects.
A: It is generally considered safe for topical use during pregnancy, but should be used only if clearly needed and under medical supervision. Avoid prolonged use or large areas.
🤔 Common Patient Concerns
🔄 Substitutes for quadriderm af cream
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin rash.
Fact: This cream is specifically for fungal infections with inflammation. Using it for other rashes can worsen the condition. - Myth: More cream means faster healing.
Fact: Applying more than a thin layer does not speed up healing and can increase side effects. - Myth: You can stop using the cream as soon as symptoms disappear.
Fact: You should complete the full course as prescribed to prevent the infection from returning.
🔄 Alternative Options
Generic Alternatives
- Betamethasone and clotrimazole cream (generic)
Brand Alternatives
- Quadriderm AF Cream
- Other brands containing betamethasone and clotrimazole