predmox eye drop - Moxifloxacin (0.5% w/v) + Prednisolone (1% w/v) medicine

Aegamox P Eye Drop: Comprehensive Guide

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🏭 Optho Remedies Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe eye pain or discomfort that does not go away.
  • Sudden vision loss or severe blurring.
  • Swelling of the face, lips, or throat, or difficulty breathing.
  • Signs of allergic reaction such as rash, itching, or hives.
  • Increased redness, swelling, or discharge from the eye.
  • Eye pain or headache with nausea or vomiting.

If experiencing severe symptoms, call emergency services immediately.

What is predmox eye drop used for?

This medicine is a combination eye drop containing moxifloxacin (an antibiotic) and prednisolone (a steroid). It is used to treat bacterial eye infections with inflammation, such as bacterial conjunctivitis, and to reduce inflammation after eye surgery. It works by killing bacteria and reducing swelling. Use it exactly as prescribed by your eye doctor.

  • Generic Name: Moxifloxacin (0.5% w/v) + Prednisolone (1% w/v)
  • Manufacturer: Optho Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 predmox eye drop के बारे में (Hindi Summary)

उपयोग: यह दवा एक संयोजन नेत्र बूंद है जिसमें मोक्सीफ्लोक्सासिन (एक एंटीबायोटिक) और प्रेडनिसोलोन (एक स्टेरॉयड) शामिल हैं। इसका उपयोग बैक्टीरियल आंखों के संक्रमण के इलाज के लिए किया जाता है जिसमें सूजन भी होती है, जैसे कि बैक्टीरियल कंजंक्टिवाइटिस, और आंखों की सर्जरी के बाद सूजन को कम करने के लिए। यह बैक्टीरिया को मारकर और सूजन को कम करके काम करती है। इसका उपयोग अपने नेत्र रोग विशेषज्ञ के निर्देशानुसार ही करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में आंखों में जलन, अस्थायी धुंधली दृष्टि, और मुंह में कड़वा स्वाद शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में एलर्जी, आंखों का बढ़ा हुआ दबाव, और द्वितीयक संक्रमण शामिल हो सकते हैं। यदि आप गंभीर आंख दर्द, सूजन, या दृष्टि में बदलाव का अनुभव करते हैं, तो तुरंत चिकित्सा सहायता लें।

सुरक्षा सलाह: उपयोग से पहले और बाद में अपने हाथ धोएं। बोतल को अच्छी तरह हिलाएं। अपने सिर को पीछे झुकाएं, निचली पलक को नीचे खींचकर एक जेब बनाएं, और प्रभावित आंख में एक बूंद डालें। आंख को धीरे से 1-2 मिनट के लिए बंद करें और आंख के भीतरी कोने को दबाएं। ड्रॉपर की नोक को आंख या किसी सतह को न छुएं। यदि आप संपर्क लेंस पहनते हैं, तो उपयोग से पहले उन्हें निकालें और कम से कम 15 मिनट बाद ही दोबारा पहनें। निर्धारित अवधि से अधिक इस दवा का उपयोग न करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 predmox eye drop Uses & Benefits

[{"condition":"Bacterial conjunctivitis with inflammation","description":"This medicine is used to treat bacterial conjunctivitis when significant inflammation is present, helping to eradicate the infection and reduce redness and swelling.","evidence":"Well-established"},{"condition":"Post-operative ocular inflammation and infection prophylaxis","description":"After eye surgery, this combination helps prevent bacterial infection and control inflammation, aiding in recovery.","evidence":"Well-established"},{"condition":"Blepharitis with bacterial infection","description":"It may be prescribed for blepharitis with a bacterial component to reduce infection and inflammation of the eyelids.","evidence":"Limited"},{"condition":"Keratitis with bacterial infection","description":"In some cases of bacterial keratitis, this combination may be used to treat infection and reduce corneal inflammation.","evidence":"Limited"}]

Off-label uses: [{"condition":"Allergic conjunctivitis with suspected secondary bacterial infection","description":"Occasionally used off-label when allergic conjunctivitis is complicated by bacterial infection, but this is not a standard indication.","evidence":"Limited"}]

Primary treatment for: Bacterial eye infections with inflammation

Also treats: Post-operative eye inflammation, Blepharitis, Keratitis

📋 Drug Information

Generic Name(s)Moxifloxacin (0.5% w/v) + Prednisolone (1% w/v)
Brand Namepredmox eye drop
ManufacturerOptho Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action Class
Route of AdministrationOphthalmic
StorageStore at room temperature (15-30°C). Protect from light and freezing. Keep the bottle tightly closed when not in use.
Shelf LifeRefer to the packaging for the expiry date. Do not use after the expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always wash your hands before and after applying this medicine to prevent contamination.
2
Shake the bottle well before each use to ensure the suspension is mixed properly.
3
Do not touch the dropper tip to your eye or any surface, as this can introduce bacteria.
4
If you are using other eye drops, wait at least 5-10 minutes between applications to avoid washing out the medicine.
5
Do not use this medicine for longer than prescribed, as prolonged use can increase the risk of side effects.
6
Attend regular follow-up appointments to monitor intraocular pressure and check for secondary infections.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Red, itchy, or watery eyes
This medicine is commonly prescribed for bacterial conjunctivitis with inflammation.
Likely Use
Eye pain and blurred vision
May be used for keratitis or post-operative inflammation.
Likely Use
Dry eyes
This medicine is not a primary treatment for dry eyes.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMoxifloxacin and prednisolone are absorbed systemically to a limited extent after topical ocular administration. Systemic absorption is generally low but can occur, especially if the eye is not properly closed after instillation.
DistributionAfter ocular administration, both drugs distribute into ocular tissues. Moxifloxacin has good penetration into the cornea and aqueous humor. Prednisolone also penetrates ocular tissues, with its distribution influenced by its lipophilicity.
Protein BindingMoxifloxacin is approximately 50% protein-bound. Prednisolone is about 70-90% protein-bound, primarily to albumin and transcortin.
MetabolismMoxifloxacin undergoes minimal metabolism, primarily by glucuronidation and sulfate conjugation. Prednisolone is metabolized in the liver, mainly by CYP3A4, to inactive metabolites.
Half-LifeThe elimination half-life of moxifloxacin is approximately 12 hours. Prednisolone has a biological half-life of 12-36 hours.
ExcretionMoxifloxacin is excreted unchanged in urine and feces. Prednisolone metabolites are excreted in urine and bile.
BioavailabilitySystemic bioavailability after ocular administration is low, estimated to be less than 5% for both components.
Onset of ActionThe antibacterial effect begins within hours, but clinical improvement may take 1-2 days. Anti-inflammatory effects may be noticed within hours.
Peak Plasma TimePeak plasma concentrations after ocular administration are typically low and occur within 1-2 hours.
Duration of ActionThe effects last for several hours; however, the dosing frequency is determined by the prescribing doctor.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Moxifloxacin, a fluoroquinolone antibiotic, inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication, repair, and transcription, leading to bacterial cell death. Prednisolone, a corticosteroid, binds to glucocorticoid receptors and suppresses the inflammatory response by inhibiting the production of inflammatory mediators and reducing immune cell activity. Together, they provide antibacterial and anti-inflammatory effects.

Mechanism Steps

1
Moxifloxacin uptake by bacteria: Moxifloxacin penetrates bacterial cells and binds to DNA gyrase and topoisomerase IV.
2
Inhibition of DNA replication: By inhibiting these enzymes, moxifloxacin prevents bacterial DNA replication and repair, leading to bacterial death.
3
Prednisolone binding to glucocorticoid receptor: Prednisolone enters ocular cells and binds to cytoplasmic glucocorticoid receptors.
4
Suppression of inflammatory genes: The prednisolone-receptor complex translocates to the nucleus and inhibits the transcription of pro-inflammatory genes, reducing inflammation.

💡 How to Take predmox eye drop

Strength: Moxifloxacin 0.5% w/v + Prednisolone 1% w/v ophthalmic suspension

1Wash your hands thoroughly with soap and water.
2Shake the bottle well before each use.
3Tilt your head back and pull down your lower eyelid to form a pouch.
4Hold the dropper above your eye and squeeze one drop into the pouch.
5Close your eye gently for 1-2 minutes and press the inner corner of your eye to reduce drainage.
6Wipe away any excess liquid with a clean tissue.
7Replace the cap tightly after use.

Dosage Information

Adult DosageThe usual adult dose is one drop instilled into the affected eye(s) as directed by your doctor. The frequency and duration depend on the condition being treated. Typically, it is used 3-4 times daily for 7-10 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are established for elderly patients. Use with caution and monitor for side effects.
Renal ImpairmentNo dosage adjustment is established for renal impairment. Use with caution.
Hepatic ImpairmentNo dosage adjustment is established for hepatic impairment. Use with caution.
Maximum Daily DoseNot established from the available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of predmox eye drop

✅ Common Side Effects

Eye irritation or burning (Common (5-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Blurred vision (Common (5-10%))
Wait until vision clears before driving or operating machinery.
Bad taste in mouth (Common (5-10%))
This is temporary and harmless. Drinking water may help.

🚨 Serious Side Effects

Allergic reaction (rash, itching, swelling) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, or throat, or difficulty breathing.
Increased intraocular pressure (Uncommon (0.1-1%))
Regular eye check-ups are needed. Report any eye pain or vision changes.
Secondary eye infection (Uncommon (0.1-1%))
Consult your doctor if you notice new or worsening symptoms.

⚠️ Rare Side Effects

Cataract formation
Long-term use may increase risk. Regular monitoring by an ophthalmologist is advised.
Corneal perforation
Seek immediate medical attention if you experience severe eye pain or vision loss.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other ophthalmic corticosteroids Major
Live vaccines Major
CYP3A4 inhibitors Moderate
NSAIDs Moderate
Anticholinergics Minor

🚨 Major Interactions

  • Other ophthalmic corticosteroids
  • Live vaccines

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • NSAIDs

🍷 Alcohol Interaction

No specific interaction is established for ophthalmic use. However, alcohol may worsen inflammation and should be consumed in moderation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to moxifloxacin, prednisolone, or any component of the formulation","Viral, fungal, or mycobacterial eye infections","Acute purulent bacterial conjunctivitis (unless directed by a doctor)","Use in children under 1 year of age (safety not established)"]

⚠️ Warnings & Precautions

["Prolonged use may increase the risk of secondary infections, increased intraocular pressure, and cataract formation.","Do not use this medicine for more than the prescribed duration.","Contact lenses should be removed before application and not reinserted for at least 15 minutes.","If you experience signs of allergic reaction, discontinue use and seek medical help.","Use with caution in patients with glaucoma or a history of herpes simplex keratitis.","Do not touch the dropper tip to any surface to avoid contamination."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to its ophthalmic route. If accidental ingestion occurs, seek medical attention. Symptoms of overdose may include systemic corticosteroid effects.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Wash your hands before and after using this medicine. Shake the bottle well before each use. Tilt your head back, pull down the lower eyelid to form a pouch, and instill one drop into the affected eye. Close your eye gently for 1-2 minutes and press the inner corner of your eye to reduce systemic absorption. Do not touch the dropper tip to your eye or any surface to avoid contamination. If you wear contact lenses, remove them before application and wait at least 15 minutes before reinserting. Do not use this medicine for longer than prescribed, as prolonged use can increase the risk of side effects. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Avoid driving or operating machinery if your vision is temporarily blurred after application.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to increased intraocular pressure and cataract formation. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning to become pregnant or are pregnant. The safety of this medicine during pregnancy is not fully established.

🏥 Post-Surgery Considerations

This medicine is often prescribed after eye surgery to prevent infection and reduce inflammation. Use exactly as directed by your surgeon.

🦷 Dental Procedures

No specific considerations for dental procedures. Inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Avoid touching or rubbing your eyes to prevent worsening of infection.
🥗
Wash your hands frequently, especially before and after applying the medicine.
😴
Do not share towels or eye makeup with others.
💧
Follow a healthy diet rich in vitamins A, C, and E to support eye health.
🧘
Get adequate rest and avoid eye strain from screens.

🏋️ Exercise Considerations

No specific exercise restrictions are established. However, if you experience blurred vision after application, avoid activities that require clear vision until it clears.

🥗 Diet Recommendations

Include foods rich in omega-3 fatty acids, such as fish and flaxseeds.
Eat plenty of fruits and vegetables rich in antioxidants.
Stay well hydrated to maintain eye moisture.

💼 Impact on Daily Work & Life

This medicine may cause temporary blurred vision after application. Avoid driving or operating heavy machinery until your vision is clear. Otherwise, it should not significantly impact your daily activities.

🛑 When to Stop This Medicine

Stop using this medicine only after completing the prescribed course or as directed by your doctor. Do not stop abruptly without consulting your doctor, as this may lead to recurrence of infection or inflammation.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to increased intraocular pressure, cataract formation, and secondary infections. Regular monitoring by an ophthalmologist is essential if prolonged use is necessary. Do not use for longer than prescribed without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Warm compresses

Can help relieve discomfort and reduce swelling in bacterial conjunctivitis.

Evidence: Limited
Lid hygiene

Regular cleaning of eyelids can help manage blepharitis.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Corticosteroids may reduce the immune response to vaccines. Consult your doctor before receiving any vaccination while using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, continue with your regular dosing schedule as prescribed; consult your doctor if adjustments are needed. Keep the bottle in your carry-on luggage to avoid loss or temperature extremes.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with bacterial conjunctivitis
She was prescribed this medicine for a bacterial eye infection with significant redness and swelling. After using it as directed for 5 days, her symptoms improved remarkably. She noted that shaking the bottle well and not touching the dropper tip were important.
💡 Lesson: Proper application technique and adherence to the prescribed duration are key to effective treatment.
👤 A 60-year-old man after cataract surgery
He was given this medicine to prevent infection and reduce inflammation after cataract surgery. He used it four times daily for a week and experienced no complications. His doctor monitored his eye pressure regularly.
💡 Lesson: Post-operative use of this medicine helps in smooth recovery, but regular monitoring is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling relief within a few hours, but it may take 1-2 days for noticeable improvement. Complete the full course as prescribed.

Q: Can I use this medicine for viral eye infection?

A: No, this medicine is only effective against bacterial infections. Using it for viral infections can be harmful.

Q: What if I forget to use it?

A: If you miss a dose, apply it as soon as you remember. If it's almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine if I have glaucoma?
  • How long can I use this medicine safely?
  • Can I wear contact lenses while using this medicine?
  • What should I do if I miss a dose?
  • Is it safe to use this medicine with other eye drops?

🔄 Substitutes for predmox eye drop

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used for any eye infection.
    Fact: This medicine is only effective against bacterial infections and should not be used for viral or fungal eye infections.
  • Myth: It is safe to use this medicine for long periods.
    Fact: Prolonged use can lead to increased eye pressure, cataracts, and secondary infections. Use only as prescribed.

🔄 Alternative Options

Generic Alternatives

  • Moxifloxacin 0.5% + Prednisolone 1% ophthalmic suspension

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Moxifloxacin + Prednisolone","primary_use":"Bacterial infection with inflammation","route":"Ophthalmic"},{"medicine":"Moxifloxacin eye drops","composition":"Moxifloxacin only","primary_use":"Bacterial infection","route":"Ophthalmic"},{"medicine":"Prednisolone eye drops","composition":"Prednisolone only","primary_use":"Inflammation","route":"Ophthalmic"}]

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