Assacab Lotion (Permethrin 5% w/v): Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, throat, difficulty breathing.
- Signs of systemic toxicity: dizziness, headache, nausea, vomiting, seizures.
- Severe skin reaction: blistering, peeling, or severe rash.
- No improvement after 2 weeks of treatment.
- Symptoms worsen or spread to other areas.
- Accidental ingestion of the lotion.
If experiencing severe symptoms, call emergency services immediately.
What is parmath lotion used for?
This medicine is a topical lotion containing permethrin 5% w/v, used to treat scabies by killing the mites and their eggs. It is applied to the skin from the neck down, left on for 8-14 hours, and then washed off.
- Generic Name: Permethrin (5% w/v)
- Manufacturer: Eclipser Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 parmath lotion के बारे में (Hindi Summary)
उपयोग: यह दवा पर्मेथ्रिन 5% w/v लोशन है, जिसका उपयोग खुजली (स्केबीज) के इलाज के लिए किया जाता है। यह त्वचा पर लगाई जाती है और खुजली पैदा करने वाले कीटाणुओं को मारती है। यह आमतौर पर गर्दन से नीचे पूरे शरीर पर लगाई जाती है और 8 से 14 घंटे तक छोड़ दी जाती है, फिर साबुन और पानी से धो ली जाती है। यह दवा बच्चों और वयस्कों दोनों के लिए उपयुक्त है, लेकिन 2 महीने से छोटे बच्चों में इसका उपयोग डॉक्टर की सलाह के बिना न करें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में लगाने की जगह पर खुजली, लालिमा या जलन शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। कभी-कभी गंभीर एलर्जी प्रतिक्रिया हो सकती है, जैसे चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई। ऐसा होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल बाहरी उपयोग के लिए है। इसे निगलें नहीं। आंखों, मुंह और अन्य श्लेष्मा झिल्ली के संपर्क से बचें। टूटी या सूजी हुई त्वचा पर न लगाएं। 2 महीने से छोटे बच्चों पर बिना डॉक्टर की सलाह के उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं उपयोग से पहले डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 parmath lotion Uses & Benefits
[{"condition":"Scabies","description":"This medicine is used to treat scabies infestation by killing the mites and their eggs.","evidence":"Well-established"},{"condition":"Lice infestation (off-label for 5% lotion)","description":"Permethrin is effective against lice, but the 5% lotion is primarily for scabies; other formulations are used for lice.","evidence":"Well-established for permethrin, but specific to formulation"}]
Off-label uses: [{"condition":"Cutaneous larva migrans","description":"Topical permethrin has been used off-label to treat creeping eruption caused by hookworm larvae.","evidence":"Limited"}]
Primary treatment for: Scabies
Also treats: Lice infestation (off-label for this formulation)
📋 Drug Information
| Generic Name(s) | Permethrin (5% w/v) |
| Brand Name | parmath lotion |
| Manufacturer | Eclipser Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Ectoparasiticides |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Keep away from direct sunlight. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Permethrin 5% is recommended by the World Health Organization for the treatment of scabies. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Permethrin acts on the nerve cell membranes of parasites by interfering with voltage-gated sodium channels. This disruption delays the closure of these channels, leading to prolonged depolarization and subsequent paralysis of the parasite. The parasite eventually dies due to inability to maintain vital functions. Permethrin has low toxicity to humans because it is poorly absorbed through intact skin and is rapidly metabolized if absorbed.
Mechanism Steps
💡 How to Take parmath lotion
Strength: Lotion, 5% w/v
Dosage Information
| Adult Dosage | For scabies: Apply a thin layer of this medicine to all skin surfaces from the neck down to the toes, including the soles of the feet. In adults, the lotion should also be applied to the scalp, forehead, temples, and ears. Leave on for 8 to 14 hours, then wash off thoroughly with soap and water. Treatment may be repeated after 7 days if live mites are still present. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | For children 2 months and older: Apply a thin layer to the entire body from the neck down, avoiding the face and scalp unless directed by a doctor. Leave on for 8 to 14 hours, then wash off. For infants under 2 months, consult a pediatrician. Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dosage adjustments are required for elderly patients. Use as directed by a healthcare provider. |
| Renal Impairment | No dosage adjustment is required for renal impairment when used topically as directed. |
| Hepatic Impairment | No dosage adjustment is required for hepatic impairment when used topically as directed. |
| Maximum Daily Dose | Not applicable for topical use. Do not apply more than the recommended amount. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of parmath lotion
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to permethrin or any component of the formulation.","Do not use on children under 2 months of age.","Do not apply to broken or inflamed skin.","Avoid contact with eyes and mucous membranes."]
⚠️ Warnings & Precautions
["For external use only. Do not ingest.","Avoid contact with eyes, mouth, and other mucous membranes.","Do not use on large areas of the body or for prolonged periods without medical advice.","If accidental ingestion occurs, seek medical attention immediately.","Keep out of reach of children.","Do not use if you are allergic to permethrin or any other ingredients.","Consult a doctor if you are pregnant or breastfeeding.","Do not use on children under 2 months of age without medical advice.","If symptoms persist after treatment, consult a doctor.","Avoid close contact with others until the lotion has dried."]
🤱 Lactation Safety
Permethrin is considered safe during breastfeeding. Apply to the affected area and avoid contact of the treated area with the infant's skin until the lotion has dried. Consult your doctor for guidance.
💊 Overdose Management
If ingested, seek immediate medical attention. Symptoms of overdose may include dizziness, headache, nausea, vomiting, and seizures. Treatment is supportive and symptomatic. If applied excessively to the skin, wash off with soap and water and consult a doctor if any adverse effects occur.
⏰ Missed Dose
This medicine is usually applied as a single application. If you miss a dose, apply it as soon as you remember, unless it is almost time for the next dose. Do not apply a double dose to make up for a missed one. Consult your doctor if you are unsure.
Additional Safety Advice
This medicine is for external use only. Do not swallow it. Avoid contact with eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to broken or inflamed skin. Do not use on children under 2 months of age unless directed by a doctor. Do not use more than the prescribed amount or more often than directed. Wash your hands thoroughly after applying the lotion, unless your hands are being treated. Avoid close contact with others until the lotion has dried, as it may transfer. Do not use this medicine if you are allergic to permethrin or any of the other ingredients. If you are pregnant or breastfeeding, consult your doctor before use. Keep out of reach of children. Store at room temperature away from direct sunlight. Do not use after the expiry date. If symptoms persist or worsen, consult your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have thinner skin and are more prone to skin irritation. Use with caution and monitor for adverse effects.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Permethrin is generally considered safe during pregnancy, but individual circumstances may vary.
🏥 Post-Surgery Considerations
No specific precautions after surgery. Consult your doctor before applying to surgical wounds.
🦷 Dental Procedures
No specific considerations for dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions are required while using this medicine. However, avoid activities that cause excessive sweating or friction on the treated area until the lotion has dried.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and left on for 8-14 hours, which may be inconvenient during work hours. It is best applied at bedtime. It does not affect driving or operating machinery.
🛑 When to Stop This Medicine
Stop using this medicine if you experience a severe allergic reaction or if your doctor advises discontinuation. Do not stop treatment prematurely unless instructed by your doctor, as scabies may not be fully eradicated.
📅 Long-Term Use Effects
Long-term effects of this medicine are not well established because it is typically used as a single application. Repeated use may increase the risk of skin irritation or allergic reactions. There is no evidence of systemic toxicity with proper topical use. If repeated treatments are needed, consult your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An alternative topical scabicide for patients who cannot use permethrin.
Evidence: Well-establishedUsed for scabies when topical treatment fails or for crusted scabies.
Evidence: Well-establishedAn older topical treatment for scabies, safe for infants and pregnant women.
Evidence: Established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. Continue routine vaccinations as scheduled.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label. Bring a copy of your prescription in case you need to show it at customs. Store it at room temperature and protect it from extreme heat or cold. If you are traveling across time zones, continue your treatment schedule as prescribed; this medicine is usually a single application, so time zone adjustments are not typically needed. If you need to reapply, follow the same instructions as at home.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts killing mites soon after application, but itching may persist for 2-4 weeks after treatment due to an allergic reaction to dead mites. If symptoms persist beyond 4 weeks, consult your doctor.
A: No, you should leave the lotion on for 8-14 hours before washing it off. Avoid bathing or swimming during this time.
A: Yes, this medicine is safe for children over 2 months of age when used as directed. For infants under 2 months, consult a pediatrician.
A: Permethrin is considered safe during pregnancy (Category B), but you should consult your doctor before use.
A: This medicine is usually a single application. If you miss a dose, apply it as soon as you remember, unless it is almost time for the next dose. Do not apply a double dose.
🤔 Common Patient Concerns
🔄 Substitutes for parmath lotion
View AllAlternative brands with exact same active ingredient:
-
scabicip lotionCipla Ltd ₹18.75 72.2% CHEAPER
-
scabiplus lotionParker Robinson Pvt Ltd ₹37.72 44% CHEAPER
-
biomethrin lotionZydus Wellness Product Ltd ₹39.40 41.5% CHEAPER
-
nedax lotionGlaxo SmithKline Pharmaceuticals Ltd ₹44.94 33.3% CHEAPER
-
perscab plus lotionElder Pharmaceuticals Ltd ₹46.17 31.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used to treat any skin rash.
Fact: This medicine is specifically for scabies and should not be used for other skin conditions without medical advice. - Myth: You can stop treatment once itching stops.
Fact: Itching may persist for weeks after successful treatment due to an allergic reaction to dead mites. Complete the full course as prescribed. - Myth: This medicine is safe to ingest.
Fact: This medicine is for external use only. Ingestion can be toxic and requires immediate medical attention.
🔄 Alternative Options
Generic Alternatives
- Permethrin 5% lotion
Brand Alternatives
- Assacab Lotion