paknet-c gel - Allantoin (0.5% w/w) + Clindamycin (1% w/w) medicine

Glintra Gel: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Percos India Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for acne vulgaris; limited for other uses.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe or persistent diarrhoea, abdominal cramps, or blood or mucus in stool.
  • Swelling of the face, lips, throat, or difficulty breathing.
  • Severe skin rash, blistering, or peeling.
  • Signs of a severe allergic reaction such as hives or fainting.
  • Yellowing of the skin or eyes (jaundice).
  • Unusual tiredness or decreased urine output.

If experiencing severe symptoms, call emergency services immediately.

What is paknet-c gel used for?

This medicine is a topical gel containing allantoin 0.5% and clindamycin 1%. It is used to treat acne by reducing bacteria and soothing the skin. Apply a thin layer to the affected area once or twice daily as prescribed.

  • Generic Name: Allantoin (0.5% w/w) + Clindamycin (1% w/w)
  • Manufacturer: Percos India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 paknet-c gel के बारे में (Hindi Summary)

उपयोग: यह दवा एक टॉपिकल जेल है जिसमें एलांटोइन 0.5% और क्लिंडामाइसिन 1% होता है। इसका उपयोग मुँहासे (एक्ने) के इलाज के लिए किया जाता है। यह त्वचा पर मौजूद बैक्टीरिया को कम करती है और त्वचा को आराम पहुँचाती है। यह दवा सूजन वाले मुँहासों को कम करने में मदद करती है और त्वचा की मरम्मत को बढ़ावा देती है। इसे डॉक्टर के निर्देशानुसार प्रभावित हिस्से पर पतली परत में लगाएँ।

साइड इफेक्ट्स: आम दुष्प्रभावों में त्वचा का सूखना, छीलना, खुजली, लालिमा या जलन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको गंभीर एलर्जी, सूजन, साँस लेने में कठिनाई, या गंभीर दस्त हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का इस्तेमाल केवल बाहरी त्वचा पर करें। आँखों, होंठों और श्लेष्मा झिल्ली के संपर्क से बचें। टूटी या जली हुई त्वचा पर न लगाएँ। उपयोग से पहले और बाद में हाथ धोएँ। धूप में जाने से बचें और सनस्क्रीन का प्रयोग करें। गर्भवती या स्तनपान कराने वाली महिलाएँ डॉक्टर से सलाह लें। बच्चों की पहुँच से दूर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 paknet-c gel Uses & Benefits

[{"condition":"Acne vulgaris","description":"Reduces inflammatory and non-inflammatory acne lesions by inhibiting Cutibacterium acnes and promoting skin healing.","evidence":"Well-established"},{"condition":"Bacterial skin infections","description":"May be used for certain superficial skin infections caused by susceptible bacteria.","evidence":"Limited"}]

Off-label uses: [{"condition":"Hidradenitis suppurativa","description":"Sometimes prescribed off-label to reduce bacterial colonisation and inflammation in mild cases.","evidence":"Limited"}]

Primary treatment for: Acne vulgaris

Also treats: Bacterial skin infections, Hidradenitis suppurativa

📋 Drug Information

Generic Name(s)Allantoin (0.5% w/w) + Clindamycin (1% w/w)
Brand Namepaknet-c gel
ManufacturerPercos India Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action Class
Route of AdministrationTopical
StorageStore at room temperature (15-30°C). Protect from light and moisture. Keep the tube tightly closed when not in use.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Apply a thin layer of the gel to the affected area after cleansing; avoid using too much as it can irritate the skin.
2
Use a gentle, non-comedogenic moisturiser to counteract dryness caused by the medicine.
3
Avoid using other topical acne treatments unless your doctor approves, as they can increase irritation.
4
Protect your skin from sun exposure by using a broad-spectrum sunscreen, as the medicine may increase sensitivity.
5
If you develop severe diarrhoea or abdominal cramps, stop using the gel and contact your doctor immediately.
6
Do not apply the gel to broken or irritated skin; wait until the skin heals.
7
Consistency is key: use the medicine regularly as prescribed to see improvement, which may take several weeks.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Inflammatory acne
This medicine is commonly prescribed for this.
Likely Use
✅
Non-inflammatory acne (blackheads, whiteheads)
It can help reduce both types of acne lesions.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Fungal skin infection
This medicine is not effective against fungi.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionClindamycin is absorbed through the skin when applied topically. Systemic absorption is generally low but can vary depending on the surface area treated, the integrity of the skin, and the use of occlusive dressings. Allantoin is minimally absorbed through intact skin.
DistributionNot established from the available information.
Protein BindingClindamycin is approximately 90% bound to plasma proteins. Allantoin binding is not established.
MetabolismClindamycin is metabolised in the liver, primarily by cytochrome P450 enzymes, to active and inactive metabolites. Allantoin is not significantly metabolised.
Half-LifeThe elimination half-life of clindamycin is approximately 2 to 3 hours. The half-life of allantoin is not established.
ExcretionClindamycin and its metabolites are excreted mainly in urine and faeces. Allantoin is excreted in urine.
BioavailabilityNot established from the available information.
Onset of ActionImprovement in acne lesions may be noticed within 2 to 4 weeks of regular use, but full benefits may take 8 to 12 weeks.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

This medicine combines two agents with complementary actions. Clindamycin binds to the 50S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and thereby stopping bacterial growth. Allantoin promotes cell proliferation and wound healing, and it helps to soften the keratin layer of the skin, facilitating the removal of dead cells and reducing irritation.

Mechanism Steps

1
Clindamycin uptake by bacteria: Clindamycin penetrates the bacterial cell wall and binds to the 50S subunit of the bacterial ribosome.
2
Inhibition of protein synthesis: By binding to the ribosome, clindamycin prevents the elongation of peptide chains, thereby inhibiting bacterial protein synthesis and stopping bacterial growth.
3
Allantoin promotes skin repair: Allantoin stimulates cell proliferation, enhances extracellular matrix formation, and softens the stratum corneum, aiding in the removal of dead skin cells and reducing irritation.

💡 How to Take paknet-c gel

Strength: Gel containing Allantoin 0.5% w/w and Clindamycin 1% w/w.

1Wash your hands thoroughly before applying the gel.
2Clean and dry the affected area gently.
3Apply a thin layer of the gel to the affected area, avoiding the eyes, lips, and mucous membranes.
4Rub it in gently until it disappears.
5Wash your hands after application.
6Use as prescribed, usually once or twice daily.

Dosage Information

Adult DosageApply a thin layer of this medicine to the affected area once or twice daily, or as directed by your doctor. Clean and dry the skin before application. The dose and frequency must be individualized by a qualified clinician based on the severity of the condition and your response to treatment. Do not apply more than prescribed.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are required for elderly patients. Use as directed by your doctor.
Renal ImpairmentNo dosage adjustment is required for topical use in patients with renal impairment, as systemic absorption is minimal.
Hepatic ImpairmentNo dosage adjustment is required for topical use in patients with hepatic impairment, as systemic absorption is minimal.
Maximum Daily DoseNot established from the available information. Use only as prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Apply the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not apply a double dose to catch up.

⚠️ Side Effects of paknet-c gel

✅ Common Side Effects

Skin dryness (Common (5-10%))
Apply a gentle moisturiser. If dryness persists, consult your doctor.
Peeling (Common (5-10%))
Avoid harsh cleansers and use a moisturiser. If peeling is severe, contact your doctor.
Itching (Common (5-10%))
Try not to scratch. If itching is bothersome, consult your doctor.
Redness (Common (5-10%))
This usually subsides with continued use. If it worsens, stop and consult your doctor.
Burning sensation (Common (5-10%))
Apply a cool compress. If burning persists, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, hives, swelling of the face or throat, or difficulty breathing.
Clostridium difficile-associated diarrhoea (Rare (<0.1%))
Seek immediate medical attention if you develop severe or persistent diarrhoea, abdominal cramps, or blood or mucus in your stool.
Severe skin irritation (Rare (<0.1%))
Discontinue use and consult your doctor if you experience severe redness, blistering, or peeling.

⚠️ Rare Side Effects

Skin discolouration
Consult your doctor if you notice any unusual skin colour changes.
Contact dermatitis
Stop using the medicine and consult your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Erythromycin Major
Neuromuscular blockers Major
Benzoyl peroxide Moderate
Salicylic acid Moderate
Retinoids Moderate
Aminoglycosides Moderate
Kaolin-pectin Minor

🚨 Major Interactions

  • Erythromycin
  • Neuromuscular blocking agents

⚡ Moderate Interactions

  • Other topical acne products (e.g., benzoyl peroxide, salicylic acid, retinoids)
  • Aminoglycosides

🍷 Alcohol Interaction

No known interaction between alcohol and this topical medicine. However, alcohol may worsen skin conditions and should be consumed in moderation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to clindamycin, lincomycin, allantoin, or any component of the gel.","History of inflammatory bowel disease or antibiotic-associated colitis.","Use on broken or irritated skin.","Not for ophthalmic, oral, or intravaginal use."]

⚠️ Warnings & Precautions

["For external use only. Avoid contact with eyes, lips, and mucous membranes.","Discontinue if severe skin irritation or allergic reaction occurs.","Prolonged use may lead to bacterial resistance or fungal overgrowth.","Use with caution in patients with a history of gastrointestinal disease, especially colitis.","Avoid concurrent use with other topical acne products unless advised by a doctor.","Sun exposure may increase irritation; use sunscreen.","Keep out of reach of children."]

🤱 Lactation Safety

Clindamycin is excreted in breast milk when taken orally, but systemic absorption from topical application is low. However, to be safe, avoid applying the gel to the breast area to prevent infant ingestion. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose with topical application is unlikely. If accidental ingestion occurs, seek medical attention immediately. Symptoms of oral clindamycin overdose may include nausea, vomiting, and diarrhoea. Treatment is symptomatic and supportive.

⏰ Missed Dose

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

Additional Safety Advice

General Safety

For external use only. Avoid contact with eyes, lips, and mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not apply to broken or irritated skin. Wash your hands before and after applying the gel. Use a gentle, non-comedogenic moisturiser if your skin becomes dry. Avoid excessive sun exposure and use sunscreen, as this medicine may make your skin more sensitive to sunlight. Do not use other topical acne products unless advised by your doctor, as they may cause irritation. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

No specific precautions for elderly patients. Use as directed by your doctor.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Topical clindamycin is generally considered safe, but your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, consult your doctor before applying this medicine to surgical wounds or nearby areas. Avoid applying to healing skin unless advised.

🦷 Dental Procedures

No specific considerations for dental procedures. Inform your dentist about all medicines you are using.

💚 Lifestyle Tips for Better Results

🏃
Cleanse your skin gently twice daily with a mild cleanser.
🥗
Avoid picking or squeezing acne lesions to prevent scarring.
😴
Use oil-free, non-comedogenic skincare products.
💧
Manage stress through relaxation techniques, as stress can worsen acne.
🧘
Maintain a balanced diet and stay hydrated.
🌞
Get adequate sleep to support skin health.

🏋️ Exercise Considerations

Exercise is generally safe while using this medicine. However, if you sweat heavily, gently cleanse your skin afterwards to prevent clogged pores. Avoid touching your face with dirty hands during workouts.

🥗 Diet Recommendations

Include plenty of fruits and vegetables rich in antioxidants.
Reduce intake of high-glycemic foods that may trigger acne.
Stay well hydrated by drinking plenty of water.
Limit dairy products if you notice they worsen your acne.

💼 Impact on Daily Work & Life

This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. You can continue your daily activities as usual. However, if you experience skin irritation, avoid activities that may exacerbate it.

🛑 When to Stop This Medicine

Do not stop using this medicine without consulting your doctor. If you experience severe side effects or your condition worsens, contact your doctor. Typically, treatment duration is determined by your doctor based on your response.

📅 Long-Term Use Effects

Long-term use of topical clindamycin may lead to bacterial resistance. It is generally recommended to use it for the shortest duration necessary. Regular follow-up with your doctor is advised to monitor efficacy and any potential side effects. Allantoin is considered safe for prolonged use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Salicylic acid cleansers

Can help unclog pores and reduce mild acne.

Evidence: Well-established
Benzoyl peroxide

Antibacterial and keratolytic, effective for mild to moderate acne.

Evidence: Well-established
Retinoids

Derivatives of vitamin A that promote cell turnover and reduce acne.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interaction between this medicine and vaccines. You can receive vaccinations while using this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription to avoid issues at customs. Store at room temperature and protect from extreme heat or cold. If travelling across time zones, continue your regular application schedule; no adjustment needed for topical use. Keep it in your carry-on luggage if flying, as checked baggage may expose it to extreme temperatures.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 22-year-old college student with moderate acne
She started using this medicine as prescribed by her dermatologist. After 4 weeks, she noticed a significant reduction in inflammatory pimples. She experienced mild dryness initially, which was managed with a moisturiser. She advises others to be patient and consistent.
💡 Lesson: Regular use and proper skin care can lead to noticeable improvement in acne over time.
👤 A 30-year-old professional with occasional breakouts
He used this medicine for mild acne and saw results within 2 weeks. He emphasizes the importance of applying it only to the affected areas and not overusing it, as it can cause irritation.
💡 Lesson: Using the medicine as directed and avoiding excessive application helps minimise side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start seeing improvement in 2 to 4 weeks, but full benefits may take 8 to 12 weeks of regular use.

Q: Can I use this medicine with other acne treatments?

A: Consult your doctor before combining with other topical acne products, as they may increase irritation.

Q: Is this medicine safe during pregnancy?

A: Topical clindamycin is generally considered safe, but consult your doctor before use.

Q: What should I do if I miss a dose?

A: Apply it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

Q: Can this medicine cause diarrhoea?

A: Rarely, clindamycin can cause severe diarrhoea. If you develop severe or persistent diarrhoea, stop using the medicine and contact your doctor immediately.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I use this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for paknet-c gel

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine works immediately.
    Fact: It may take several weeks to see noticeable improvement.
  • Myth: More application means faster results.
    Fact: Applying more than prescribed can increase irritation without improving efficacy.
  • Myth: It can be used on any skin infection.
    Fact: It is specifically for acne and certain bacterial skin infections; consult a doctor for other conditions.

🔄 Alternative Options

Generic Alternatives

  • Allantoin 0.5% + Clindamycin 1% gel (generic)

Brand Alternatives

  • Glintra Gel

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Allantoin 0.5% + Clindamycin 1%","uses":"Acne vulgaris","notes":"Soothing and antibacterial"},{"medicine":"Clindamycin 1% gel","composition":"Clindamycin 1%","uses":"Acne vulgaris","notes":"Antibacterial only"},{"medicine":"Clindamycin 1% + Benzoyl peroxide 5% gel","composition":"Clindamycin 1% + Benzoyl peroxide 5%","uses":"Acne vulgaris","notes":"Antibacterial and keratolytic"}]

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