olmewon am 40 tablet - Olmesartan Medoxomil (40mg) + Amlodipine (5mg) medicine

Olmesar A 40 Tablet: Complete Guide to Uses, Side Effects, and Safety

No reviews yet
🏭 Walron Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not recommended. Use of this medicine during pregnancy can cause harm to the fetus. Consult your doctor immediately if you become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Swelling of face, lips, tongue, or throat
  • Chest pain or difficulty breathing
  • Decreased urine output or swelling in legs
  • Irregular heartbeat or palpitations
  • Severe headache with visual changes

If experiencing severe symptoms, call emergency services immediately.

What is olmewon am 40 tablet used for?

This medicine is a combination of Olmesartan Medoxomil 40 mg and Amlodipine 5 mg used to treat high blood pressure. It works by relaxing blood vessels and reducing the heart's workload. It is taken once daily, usually with or without food.

  • Generic Name: Olmesartan Medoxomil (40mg) + Amlodipine (5mg)
  • Manufacturer: Walron Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 olmewon am 40 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। यह ओल्मेसार्टन मेडोक्सोमिल और एम्लोडिपिन का संयोजन है, जो रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है। यह उन रोगियों के लिए निर्धारित की जाती है जिनका रक्तचाप एक दवा से नियंत्रित नहीं होता। इसे रोजाना एक बार लेना चाहिए, चिकित्सक के निर्देशानुसार।

साइड इफेक्ट्स: आम दुष्प्रभावों में चक्कर आना, सिरदर्द, टखनों में सूजन और थकान शामिल हैं। ये आमतौर पर हल्के होते हैं और समय के साथ सुधर जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको बेहोशी, गंभीर चक्कर या सूजन बढ़ती है तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को चिकित्सक के निर्देशानुसार ही लें। शराब से बचें क्योंकि इससे चक्कर बढ़ सकते हैं। अचानक उठने से बचें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। नियमित रूप से रक्तचाप और गुर्दे की जांच कराएं। दवा अचानक बंद न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 olmewon am 40 tablet Uses & Benefits

[{"condition":"Hypertension","description":"Used to lower high blood pressure when monotherapy is insufficient.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Hypertension

Also treats: Angina, Heart failure

📋 Drug Information

Generic Name(s)Olmesartan Medoxomil (40mg) + Amlodipine (5mg)
Brand Nameolmewon am 40 tablet
ManufacturerWalron Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood pressure control.
2
Monitor your blood pressure regularly and keep a record to share with your doctor.
3
Avoid alcohol as it can increase dizziness and low blood pressure.
4
Do not stop this medicine suddenly without consulting your doctor.
5
Report any swelling, dizziness, or unusual symptoms to your doctor promptly.
6
Stay hydrated and maintain a low-salt diet to enhance the medicine's effect.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionOlmesartan Medoxomil is rapidly absorbed after oral administration, with peak plasma concentration reached in 1-2 hours. Amlodipine is also well absorbed orally, with peak levels at 6-12 hours. Food does not significantly affect the absorption of either component.
DistributionBoth components are widely distributed in the body. Olmesartan is highly protein-bound, while amlodipine has moderate protein binding. Amlodipine crosses the blood-brain barrier minimally.
Protein BindingOlmesartan Medoxomil is approximately 99% protein-bound. Amlodipine is about 93% protein-bound.
MetabolismOlmesartan Medoxomil is metabolized in the liver to inactive metabolites. Amlodipine is extensively metabolized in the liver, primarily by CYP3A4.
Half-LifeThe elimination half-life of olmesartan is approximately 13 hours. Amlodipine has a long half-life of 30-50 hours.
ExcretionOlmesartan is excreted mainly in feces (via bile) and urine. Amlodipine is excreted in urine as metabolites.
BioavailabilityThe absolute bioavailability of olmesartan is about 26%. Amlodipine has a bioavailability of 64-90%.
Onset of ActionBlood pressure lowering effect begins within 1-2 weeks, with maximal effect after 4-8 weeks.
Peak Plasma TimeOlmesartan: 1-2 hours; Amlodipine: 6-12 hours.
Duration of ActionBoth components provide 24-hour blood pressure control with once-daily dosing.

How It Works

This medicine combines two antihypertensive agents with complementary mechanisms. Olmesartan Medoxomil blocks the action of angiotensin II at the AT1 receptor, leading to vasodilation and reduced aldosterone secretion. Amlodipine inhibits calcium influx into vascular smooth muscle and cardiac muscle, causing vasodilation and reduced peripheral resistance. The combined effect lowers blood pressure more effectively than either agent alone.

Mechanism Steps

1
Olmesartan blocks AT1 receptors: Olmesartan Medoxomil selectively binds to AT1 receptors in vascular smooth muscle, preventing angiotensin II from causing vasoconstriction.
2
Reduced aldosterone secretion: Blockade of AT1 receptors decreases aldosterone release, leading to reduced sodium and water retention.
3
Amlodipine inhibits calcium channels: Amlodipine blocks L-type calcium channels in vascular smooth muscle, reducing calcium entry and causing relaxation.
4
Vasodilation and reduced peripheral resistance: The combined actions lead to dilation of blood vessels and decreased peripheral vascular resistance, lowering blood pressure.

💡 How to Take olmewon am 40 tablet

Strength: Tablet: Olmesartan Medoxomil 40 mg + Amlodipine 5 mg

1Take the tablet at the same time each day, with or without food.
2Swallow the tablet whole with a glass of water.
3Do not crush or chew the tablet.
4If you have a sensitive stomach, take it with a meal.
5Follow your doctor's instructions exactly.

Dosage Information

Adult DosageThe usual adult dose is one tablet once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo dose adjustment is usually needed for mild to moderate renal impairment. For severe renal impairment, consult a doctor. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. Contraindicated in severe hepatic impairment. Dose must be individualized by a qualified clinician.
Maximum Daily DoseOne tablet daily (Olmesartan 40 mg + Amlodipine 5 mg). Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Take at the same time daily
Food does not significantly affect absorption.
Grapefruit
Avoid
May increase amlodipine levels.
High-potassium foods
Moderate intake
Olmesartan may increase potassium levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of olmewon am 40 tablet

✅ Common Side Effects

Dizziness (Common (up to 10%))
Rise slowly from sitting or lying position. Avoid driving if dizzy.
Headache (Common (5-10%))
Usually resolves. Take paracetamol if needed, but consult doctor if persistent.
Peripheral edema (swelling of ankles/feet) (Common (5-10%))
Elevate legs when resting. Report if severe or bothersome.
Fatigue (Common (5-10%))
Ensure adequate rest. Consult if it interferes with daily activities.

🚨 Serious Side Effects

Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you experience fainting or severe dizziness.
Acute kidney injury (Rare (<0.1%))
Report decreased urine output or swelling. Regular kidney function tests are advised.
Angioedema (Very rare (<0.01%))
Seek emergency care if you notice swelling of face, lips, tongue, or throat.

⚠️ Rare Side Effects

Hyperkalemia
Monitor potassium levels if on other medications. Report muscle weakness or irregular heartbeat.
Rhabdomyolysis
Seek immediate care for unexplained muscle pain, tenderness, or dark urine.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Potassium supplements Major
Lithium Major
NSAIDs Major
CYP3A4 inhibitors Moderate
CYP3A4 inducers Moderate

🚨 Major Interactions

  • Potassium supplements or potassium-sparing diuretics
  • Lithium
  • NSAIDs

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampicin, carbamazepine)

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect and increase dizziness. It is advisable to limit or avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","Severe liver impairment","Allergy to olmesartan, amlodipine, or any component","Biliary obstruction"]

⚠️ Warnings & Precautions

["Avoid use in pregnancy. Use effective contraception.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Monitor kidney function and potassium levels regularly.","Do not stop abruptly; taper under medical supervision.","Inform your doctor if you have liver or kidney disease."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe hypotension and reflex tachycardia. Seek immediate medical attention. Treatment is supportive and symptomatic. Gastric lavage may be considered if taken recently. Monitor vital signs and electrolytes.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed, usually once daily. Do not change the dose without consulting your doctor. Avoid alcohol as it may increase dizziness. Stand up slowly to prevent falls if you feel dizzy. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Regular blood pressure monitoring and kidney function tests are important. Do not stop this medicine abruptly, as it can cause rebound high blood pressure.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely for dizziness and falls.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative before conception.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before surgery. It may need to be temporarily stopped. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. It may interact with certain anesthetics or affect blood pressure during the procedure.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular physical activity like walking or swimming.
😴
Reduce salt intake to enhance the medicine's effect.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like yoga or meditation.
🌞
Get adequate sleep and follow a consistent sleep schedule.

🏋️ Exercise Considerations

Moderate exercise is encouraged, but avoid sudden strenuous activity if you feel dizzy. Stay hydrated and monitor your blood pressure before and after exercise.

🥗 Diet Recommendations

Follow a low-sodium diet.
Include potassium-rich foods like bananas and spinach in moderation.
Limit processed and fried foods.
Stay well hydrated.
Avoid excessive caffeine.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, especially when standing up quickly. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their daily activities with caution.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Stopping suddenly can cause rebound high blood pressure. Your doctor may adjust or discontinue based on your condition.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored. Regular check-ups for blood pressure, kidney function, and electrolytes are recommended. It may reduce the risk of cardiovascular events. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help lower blood pressure.

Evidence: Well-established
Other antihypertensive combinations

Your doctor may prescribe alternative combinations if needed.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Continue routine vaccinations as advised by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip and carry it in your hand luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with uncontrolled hypertension
He was prescribed this medicine after his blood pressure remained high on a single drug. Within a month, his blood pressure stabilized, and he experienced only mild dizziness initially. He now walks daily and follows a low-salt diet.
💡 Lesson: Combination therapy can effectively control blood pressure when monotherapy fails. Lifestyle changes enhance results.
👤 A 62-year-old woman with hypertension and mild ankle swelling
She started this medicine and noticed ankle swelling after two weeks. Her doctor advised elevating her legs and reducing salt intake. The swelling reduced, and her blood pressure remained well-controlled.
💡 Lesson: Mild side effects like ankle swelling can be managed with simple measures. Always inform your doctor about new symptoms.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1-2 weeks, with maximal effect after 4-8 weeks.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my other blood pressure medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for olmewon am 40 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often requires long-term treatment. Stopping suddenly can cause rebound hypertension.
  • Myth: This medicine causes kidney damage in everyone.
    Fact: Kidney problems are rare and can be monitored. Regular check-ups help prevent complications.

🔄 Alternative Options

Generic Alternatives

  • Olmesartan Medoxomil + Amlodipine generic tablets

Brand Alternatives

  • Olmesar A 40 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Olmesartan + Amlodipine","composition":"Olmesartan Medoxomil 40 mg + Amlodipine 5 mg","onset":"1-2 weeks","duration":"24 hours","notes":"This medicine"},{"medicine":"Telmisartan + Amlodipine","composition":"Telmisartan 40 mg + Amlodipine 5 mg","onset":"1-2 weeks","duration":"24 hours","notes":"Similar efficacy"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory