Dermup Cream: A Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, throat, difficulty breathing.
- Severe skin reaction: blistering, peeling, or severe rash.
- Signs of infection: increased redness, warmth, swelling, or pus at the application site.
- No improvement after 2 weeks of treatment.
- Symptoms worsen or spread to other areas.
- Accidental ingestion of the cream, especially in children.
If experiencing severe symptoms, call emergency services immediately.
What is nukenz lotion used for?
This medicine is a topical cream containing permethrin, used to treat scabies, head lice, and pubic lice. It works by killing the parasites. Apply as directed by your doctor, usually leaving it on for 8-14 hours for scabies or 10 minutes for lice, then wash off.
- Generic Name: Permethrin (NA)
- Manufacturer: Pharm Products Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nukenz lotion के बारे में (Hindi Summary)
उपयोग: यह दवा परमेथ्रिन क्रीम है, जिसका उपयोग खुजली (स्केबीज), जूँ (हेड लाइस) और जननांग जूँ (प्यूबिक लाइस) के इलाज के लिए किया जाता है। यह परजीवियों को मारकर काम करती है। इसे डॉक्टर के निर्देशानुसार प्रभावित त्वचा पर लगाएं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर खुजली, लालिमा या झुनझुनी शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। यदि आपको गंभीर एलर्जी या त्वचा पर छाले जैसे लक्षण दिखें, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग करते समय सावधानी बरतें: आंखों, मुंह और अन्य श्लेष्मा झिल्ली के संपर्क से बचें। यदि संपर्क हो जाए तो पानी से अच्छी तरह धो लें। टूटी या जली हुई त्वचा पर न लगाएं। बच्चों में 2 महीने से कम उम्र में उपयोग न करें। गर्भवती महिलाएं डॉक्टर से परामर्श करें। उपयोग के बाद हाथ धो लें।
💊 nukenz lotion Uses & Benefits
- [{"condition":"Scabies","description":"This medicine is used to treat scabies infestation by killing the mites and their eggs.
- It is applied to the entire body from the neck down, left on for 8-14 hours, and then washed off.","evidence":"Well-established"},{"condition":"Head lice","description":"This medicine is used to treat head lice infestation by killing the lice and their eggs.
- It is applied to the scalp and hair, left on for 10 minutes, and then rinsed off.","evidence":"Well-established"},{"condition":"Pubic lice","description":"This medicine is used to treat pubic lice infestation by killing the lice and their eggs.
- It is applied to the affected area and left on for 10 minutes before washing off.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Cutaneous larva migrans","description":"Sometimes used off-label to treat creeping eruption caused by hookworm larvae.","evidence":"Limited"}]
Primary treatment for: Scabies
Also treats: Head lice infestation, Pubic lice infestation
📋 Drug Information
| Generic Name(s) | Permethrin (NA) |
| Brand Name | nukenz lotion |
| Manufacturer | Pharm Products Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Ectoparasiticides |
| Route of Administration | Topical |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from direct sunlight and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Permethrin 5% cream is recommended by the World Health Organization for the treatment of scabies. |
| ICMR Guideline | The Indian Council of Medical Research recommends permethrin for the treatment of scabies and lice infestations. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Permethrin, the active ingredient in this medicine, is a synthetic pyrethroid that acts on the nervous system of parasites. It binds to voltage-gated sodium channels in the nerve cells, delaying their closure and causing prolonged depolarization. This leads to hyperexcitation, paralysis, and eventually death of the mites or lice. Permethrin has low toxicity to humans because it is poorly absorbed through the skin and is rapidly metabolized if absorbed.
Mechanism Steps
💡 How to Take nukenz lotion
Strength: Cream containing permethrin 5% w/w.
Dosage Information
| Adult Dosage | For scabies: Apply a thin layer of this medicine to the entire body from the neck down to the toes, including the soles of the feet. Leave on for 8 to 14 hours, then wash off thoroughly with soap and water. For head lice: Apply to the scalp and hair, leave on for 10 minutes, then rinse off. For pubic lice: Apply to the affected area, leave on for 10 minutes, then wash off. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | For children 2 months and older, the dosage is the same as for adults, but use with caution. For infants under 2 months, consult a pediatrician. Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dosage adjustments are required for elderly patients. However, use with caution and follow the prescribed instructions. |
| Renal Impairment | No dosage adjustment is necessary for patients with renal impairment due to minimal systemic absorption. |
| Hepatic Impairment | No dosage adjustment is necessary for patients with hepatic impairment due to minimal systemic absorption. |
| Maximum Daily Dose | The maximum daily dose is not applicable as this medicine is used as a single application per treatment course. Do not exceed the prescribed frequency. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nukenz lotion
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to permethrin or any component of the formulation.","Use on broken or inflamed skin is not recommended unless directed by a physician.","Not for use in children under 2 months of age."]
⚠️ Warnings & Precautions
["For external use only. Avoid contact with eyes, mouth, and mucous membranes.","If accidental contact occurs, rinse thoroughly with water.","Do not apply to areas of the skin that are broken or irritated.","Wash hands after application unless hands are being treated.","Avoid using other topical medications on the same area unless instructed.","Keep out of reach of children.","If condition persists or worsens, consult a doctor.","Do not use for prolonged periods without medical advice."]
🤱 Lactation Safety
Permethrin is considered safe during breastfeeding. Apply to the breast area only if necessary, and wash thoroughly before nursing to prevent infant ingestion.
💊 Overdose Management
Overdose with topical permethrin is unlikely due to low systemic absorption. If accidental ingestion occurs, seek immediate medical attention. Symptoms of ingestion may include nausea, vomiting, headache, dizziness, and in severe cases, seizures. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
For safe and effective use of this medicine, apply it exactly as prescribed by your doctor. Avoid contact with eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water. Do not use this medicine on children under 2 months of age unless directed by a doctor. Pregnant women should consult their doctor before using this medicine. Do not apply to broken or irritated skin. Wash your hands thoroughly after applying the cream, unless your hands are being treated. Avoid using other topical products on the same area unless instructed. Keep this medicine out of reach of children. If you are breastfeeding, avoid applying the cream to the breast area to prevent ingestion by the infant. Do not use this medicine for any condition other than that for which it was prescribed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients can use this medicine safely. However, they may be more prone to skin irritation. Monitor for any adverse reactions and consult a doctor if needed.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Permethrin is considered safe during pregnancy, but individual circumstances may vary.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, consult your doctor before applying this medicine to surgical sites or nearby areas to avoid irritation or infection.
🦷 Dental Procedures
No specific considerations for dental procedures. This medicine is for topical use and does not interact with dental treatments.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions while using this medicine. However, avoid swimming or excessive sweating immediately after application to ensure the medicine stays on the skin for the required duration.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to work or drive. However, if you experience dizziness or drowsiness (rare), avoid driving or operating machinery until you feel alert.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if you experience severe skin irritation, allergic reactions, or if your condition does not improve after the recommended treatment period. Do not stop treatment prematurely without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to skin irritation or allergic reactions. If you require repeated treatments, consult your doctor to confirm the diagnosis and rule out other conditions.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An oral medication for scabies, used when topical treatment fails or is not tolerated.
Evidence: Well-establishedAn alternative topical treatment for scabies, but less effective than permethrin.
Evidence: ModerateAn older topical treatment for scabies, safe for infants and pregnant women.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions between this medicine and vaccines. You can receive vaccinations while using this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it at room temperature and protect it from extreme heat or cold. If you are traveling across time zones, continue using it as prescribed; no time zone adjustment is needed for topical application. Declare it at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts killing parasites soon after application, but itching may persist for up to 4 weeks as the skin heals. If symptoms persist beyond 2 weeks, consult your doctor.
A: This medicine should not be applied to the face unless specifically directed by a doctor, as it can cause irritation to sensitive areas.
A: Yes, it is safe for children 2 months and older when used as directed. For infants under 2 months, consult a pediatrician.
A: Yes, for scabies, all household members and close contacts should be treated simultaneously to prevent reinfestation.
A: Permethrin is considered safe during pregnancy (Category B). However, consult your doctor before use.
A: Apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: No, there are no food restrictions as this medicine is for topical use.
A: No, this medicine is specifically for scabies and lice infestations. Do not use it for other conditions unless prescribed by a doctor.
🤔 Common Patient Concerns
🔄 Substitutes for nukenz lotion
View AllAlternative brands with exact same active ingredient:
-
scabigo lotionTorque Pharmaceuticals Pvt Ltd ₹17.07 43.4% CHEAPER
-
scarbic creamLeeford Healthcare Ltd ₹21.91 27.3% CHEAPER
-
scabilice creamParker Robinson Pvt Ltd ₹24.99 17.1% CHEAPER
-
permiscab lotionParry Pharma Pvt Ltd ₹41.34 37.2% COSTLIER
-
olscab p soapAmpra Pharmaceuticals ₹42.86 42.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of skin itching.
Fact: This medicine is only effective against scabies and lice infestations, not other causes of itching. - Myth: You only need to apply this medicine once and the infestation is gone.
Fact: While one application may be sufficient, sometimes a second treatment after 7-14 days is needed to kill newly hatched mites. - Myth: This medicine is safe to use on the face without precautions.
Fact: It should not be applied to the face unless specifically directed by a doctor, as it can cause irritation.
🔄 Alternative Options
Generic Alternatives
- Permethrin 5% cream
Brand Alternatives
- Permite
- Scabper