Nuforce Plus 150 Mg/6 Mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Confusion, tremors, or seizures
If experiencing severe symptoms, call emergency services immediately.
What is nuforce plus 150 mg/6 mg tablet used for?
This medicine is a prescription combination of fluconazole (an antifungal) and ivermectin (an antiparasitic) used for specific mixed infections. It should only be taken under medical supervision.
- Generic Name: Fluconazole (150mg) + Ivermectin (6mg)
- Manufacturer: Mankind Pharma Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nuforce plus 150 mg/6 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फ्लुकोनाज़ोल और आइवरमेक्टिन का संयोजन है, जिसका उपयोग कुछ विशेष फंगल और परजीवी संक्रमणों के इलाज के लिए किया जाता है। यह डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, मतली, पेट दर्द, दस्त और दाने शामिल हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें एलर्जी, लीवर की समस्या, त्वचा की गंभीर प्रतिक्रियाएं और तंत्रिका संबंधी लक्षण शामिल हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब का सेवन न करें। गर्भावस्था और स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को रूम टेम्परेचर पर सूखी जगह पर रखें। बच्चों की पहुंच से दूर रखें।
💊 nuforce plus 150 mg/6 mg tablet Uses & Benefits
[{"condition":"Mixed fungal and parasitic infections","description":"Used in specific cases where both fungal and parasitic infections are present, such as in immunocompromised patients.","evidence":"Limited"},{"condition":"Fungal infections (fluconazole component)","description":"Fluconazole is used to treat candidiasis, cryptococcosis, and other fungal infections.","evidence":"Well-established for fluconazole alone"},{"condition":"Parasitic infections (ivermectin component)","description":"Ivermectin is used to treat strongyloidiasis, onchocerciasis, scabies, and other parasitic infestations.","evidence":"Well-established for ivermectin alone"}]
Off-label uses: [{"condition":"COVID-19","description":"Ivermectin has been investigated for COVID-19 but is not approved for this use.","evidence":"Insufficient"},{"condition":"Rosacea","description":"Ivermectin topical is used for rosacea, but oral use is not standard.","evidence":"Limited"}]
Primary treatment for: Mixed fungal and parasitic infections
Also treats: Candidiasis, Strongyloidiasis, Onchocerciasis, Scabies
📋 Drug Information
| Generic Name(s) | Fluconazole (150mg) + Ivermectin (6mg) |
| Brand Name | nuforce plus 150 mg/6 mg tablet |
| Manufacturer | Mankind Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information for the combination product. Fluconazole and ivermectin are individually recommended by WHO for specific infections. |
| ICMR Guideline | Not established from the available information for the combination product. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Fluconazole selectively inhibits fungal cytochrome P450 enzymes, particularly lanosterol 14-alpha-demethylase, which converts lanosterol to ergosterol. This leads to a defective fungal cell membrane and accumulation of toxic sterols. Ivermectin binds to glutamate-gated chloride channels and GABA receptors in parasites, causing hyperpolarization of nerve and muscle cells, leading to paralysis and death of the parasite. In humans, ivermectin does not readily cross the blood-brain barrier at therapeutic doses, but can cause central nervous system effects if the barrier is compromised.
Mechanism Steps
💡 How to Take nuforce plus 150 mg/6 mg tablet
Strength: Tablet containing fluconazole 150 mg and ivermectin 6 mg.
Dosage Information
| Adult Dosage | The dosage of this medicine is individualized by a qualified clinician based on the specific infection, its severity, patient's age, weight, renal and hepatic function, and other medications. It is typically taken as a single dose or as a short course. Do not self-medicate. Follow your doctor's prescription exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal and hepatic function. Use with caution and monitor closely. |
| Renal Impairment | Fluconazole dose should be reduced in patients with renal impairment. Ivermectin does not require renal dose adjustment, but use with caution. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Monitor liver function. |
| Maximum Daily Dose | Not established from the available information. Follow your doctor's prescription. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nuforce plus 150 mg/6 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| CYP3A4 inhibitors | Major | |
| CYP3A4 inducers | Major | |
| Statins | Moderate | |
| Sulfonylureas | Moderate | |
| Phenytoin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
⚡ Moderate Interactions
- Statins (e.g., atorvastatin, simvastatin)
- Sulfonylureas (e.g., glipizide, glyburide)
- Phenytoin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol may increase the risk of liver toxicity, especially with fluconazole, and may worsen side effects such as dizziness and nausea.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to fluconazole, ivermectin, or any component of the formulation","Concurrent use with certain drugs that prolong QT interval","Severe liver disease","Pregnancy (unless clearly needed)","Breastfeeding (unless clearly needed)"]
⚠️ Warnings & Precautions
["Use with caution in patients with liver or kidney disease.","Avoid alcohol during treatment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Use effective contraception during treatment and for at least one week after.","Do not use in patients with a history of severe allergic reactions to azoles or avermectins.","Monitor for signs of liver toxicity.","Use with caution in patients with neurological disorders."]
🤱 Lactation Safety
Fluconazole and ivermectin are excreted in breast milk. Consult your doctor before breastfeeding. Breastfeeding is not recommended while taking this medicine.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and neurological symptoms. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Hemodialysis may be considered for fluconazole overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not self-medicate or share this medicine with others. Inform your doctor about all your medical conditions, especially liver or kidney problems, and any allergies. Avoid alcohol while taking this medicine as it may increase the risk of liver damage. Use effective contraception during treatment and for at least one week after the last dose if you are of childbearing age. Do not breastfeed while taking this medicine without consulting your doctor. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Do not double the dose. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects, especially liver and kidney toxicity. Dose adjustment may be needed based on renal and hepatic function. Monitor closely.
🤰 Pregnancy Planning (TTC)
This medicine should be avoided during pregnancy unless clearly needed. Use effective contraception during treatment and for at least one week after. Consult your doctor if you are planning pregnancy.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with other medications used during surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue, avoid strenuous exercise until you know how the medicine affects you. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Take rest if needed.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Complete the full course as prescribed, even if you feel better. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of liver toxicity, especially with fluconazole. Regular monitoring of liver function is recommended. Ivermectin long-term use may lead to neurological side effects. Use only as prescribed and for the recommended duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For localized fungal infections, topical treatments may be sufficient.
Evidence: Well-establishedFor scabies, topical permethrin is an alternative.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about dose timing. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The onset of action depends on the type of infection. Improvement may be seen within a few days, but complete treatment may take longer. Follow your doctor's instructions.
A: Inform your doctor about all medications you are taking, as this medicine can interact with several drugs. Do not start any new medication without consulting your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for nuforce plus 150 mg/6 mg tablet
View AllAlternative brands with exact same active ingredient:
-
flumet plus 150mg/6mg tabletLeeford Healthcare Ltd ₹17.72 22.9% CHEAPER
-
Fanna I 150mg/6mg TabletGenesis Biotech Inc ₹19.00 17.4% CHEAPER
-
fluchy plus 150mg/6mg tabletHelplab Healthcare Pvt Ltd ₹26.50 15.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of infections.
Fact: It is only effective against susceptible fungal and parasitic infections, not bacterial or viral infections. - Myth: It is safe to take without a prescription.
Fact: It is a prescription medicine and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Fluconazole 150 mg + Ivermectin 6 mg tablet (generic)
Brand Alternatives
- Nuforce Plus 150 mg/6 mg tablet