Zocon 50 Dt Tablet (fluconazole 50mg): Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of skin or eyes (jaundice)
- Severe abdominal pain or vomiting blood
- Bloody diarrhea
- Difficulty breathing or swelling of face, lips, or throat
- Palpitations or fainting
- Seizures
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is nuforce 50mg tablet used for?
This medicine is an antifungal used to treat various fungal infections. It works by disrupting the fungal cell membrane. The typical adult dose for vaginal thrush is a single 150 mg dose, but dosing varies by infection. Always follow your doctor's prescription.
- Generic Name: Fluconazole (50mg)
- Manufacturer: Mankind Pharma Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nuforce 50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फंगल संक्रमण के इलाज के लिए उपयोग की जाती है, जैसे योनि में खमीर संक्रमण, मुंह में छाले, गले में फंगल संक्रमण, और गंभीर फंगल संक्रमण। यह फंगस को मारती है और संक्रमण को फैलने से रोकती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, जी मिचलाना, पेट दर्द, दस्त, और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें लिवर की समस्या, एलर्जी, और दिल की धड़कन में गड़बड़ी शामिल हो सकती है।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। लिवर या किडनी की बीमारी हो तो सावधानी बरतें। दवा को ठंडी और सूखी जगह पर रखें।
💊 nuforce 50mg tablet Uses & Benefits
[{"condition":"Vaginal candidiasis (thrush)","description":"This medicine is used as a single oral dose to treat vaginal yeast infections caused by Candida species.","evidence":"Well-established"},{"condition":"Oropharyngeal candidiasis (oral thrush)","description":"This medicine is used to treat fungal infections of the mouth and throat, often in immunocompromised patients.","evidence":"Well-established"},{"condition":"Esophageal candidiasis","description":"This medicine is used to treat fungal infections of the esophagus, particularly in patients with HIV/AIDS or other immunocompromising conditions.","evidence":"Well-established"},{"condition":"Cryptococcal meningitis","description":"This medicine is used in the treatment of cryptococcal meningitis, a serious fungal infection of the brain and spinal cord.","evidence":"Well-established"},{"condition":"Systemic candidiasis","description":"This medicine is used to treat disseminated fungal infections in the bloodstream and internal organs.","evidence":"Well-established"},{"condition":"Prevention of fungal infections in immunocompromised patients","description":"This medicine is used prophylactically in patients undergoing bone marrow transplantation or those with advanced HIV.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Tinea versicolor","description":"Sometimes prescribed off-label for skin fungal infections, though topical agents are preferred.","evidence":"Limited"},{"condition":"Onychomycosis","description":"Occasionally used off-label for nail fungal infections, but requires prolonged therapy and is not first-line.","evidence":"Limited"}]
Primary treatment for: Fungal infections
Also treats: Vaginal candidiasis, Oropharyngeal candidiasis, Esophageal candidiasis, Cryptococcal meningitis, Systemic candidiasis
📋 Drug Information
| Generic Name(s) | Fluconazole (50mg) |
| Brand Name | nuforce 50mg tablet |
| Manufacturer | Mankind Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the fungal cytochrome P450 enzyme 14-alpha-demethylase, which is responsible for converting lanosterol to ergosterol. Ergosterol is a critical component of the fungal cell membrane. By blocking this step, the medicine disrupts membrane integrity, leading to leakage of cellular contents and fungal cell death. It is selective for fungal enzymes over human enzymes, which reduces toxicity to human cells.
Mechanism Steps
💡 How to Take nuforce 50mg tablet
Strength: Dispersible tablet, 50 mg
Dosage Information
| Adult Dosage | The dose of this medicine varies depending on the type and severity of the fungal infection. For vaginal candidiasis, a single 150 mg dose is typical. For oral thrush, 50-100 mg once daily for 7-14 days may be used. For systemic infections, doses may range from 200-400 mg daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function and may require dose adjustment. Use with caution and monitor renal function. |
| Renal Impairment | In patients with renal impairment, dose reduction is necessary. For creatinine clearance less than 50 mL/min, the dose should be reduced by 50%. Consult a healthcare professional for specific dosing. |
| Hepatic Impairment | In patients with hepatic impairment, no specific dose adjustment is provided, but caution is advised. Monitor liver function closely. |
| Maximum Daily Dose | The maximum daily dose is not established from available information. Doses up to 400 mg daily have been used in clinical practice for serious infections, but must be determined by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nuforce 50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Simvastatin | Major | |
| Amiodarone | Major | |
| Phenytoin | Major | |
| Rifampicin | Major | |
| Glipizide | Moderate | |
| Cyclosporine | Moderate | |
| Midazolam | Moderate | |
| Antacids | Minor | |
| Cimetidine | Minor |
🚨 Major Interactions
- Warfarin
- Statins (e.g., simvastatin, atorvastatin)
- QT-prolonging drugs (e.g., amiodarone, sotalol)
- Phenytoin
- Rifampicin
⚡ Moderate Interactions
- Sulfonylureas (e.g., glipizide, glyburide)
- Cyclosporine
- Tacrolimus
- Benzodiazepines (e.g., midazolam, triazolam)
🍷 Alcohol Interaction
Alcohol may increase the risk of liver toxicity and should be avoided while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to fluconazole or other azole antifungals.","Concurrent use with cisapride, terfenadine, or astemizole due to risk of serious cardiac arrhythmias.","Concurrent use with erythromycin in patients with QT prolongation.","Breastfeeding."]
⚠️ Warnings & Precautions
["Use with caution in patients with liver disease; dose adjustment may be needed.","Use with caution in patients with kidney disease; dose adjustment may be needed.","May cause dizziness or seizures; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol during treatment.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not use for fungal infections that are not confirmed by a healthcare professional.","Complete the full course as prescribed to prevent recurrence."]
🤱 Lactation Safety
This medicine is excreted in breast milk at concentrations similar to plasma. Breastfeeding is not recommended while taking this medicine.
💊 Overdose Management
Overdose may cause hallucinations, paranoid behavior, and vomiting. Treatment is supportive and symptomatic. In case of overdose, seek immediate medical attention. Hemodialysis may reduce blood levels.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not share it with others. Inform your doctor if you have liver or kidney problems, heart conditions, or are taking other medications. Avoid alcohol while taking this medicine. Use effective contraception during treatment and for one week after the last dose if you are of childbearing potential. Do not breastfeed while taking this medicine. Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and may require dose adjustment. Monitor for side effects and drug interactions.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Use effective contraception during treatment and for one week after the last dose.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine, as it may interact with other medications used during surgery. It does not typically affect surgical outcomes.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with medications used in dental procedures. No specific precautions are usually needed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness. Avoid strenuous exercise or operating machinery until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue normal activities if you feel well.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early may lead to recurrence of infection. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of liver toxicity and fungal resistance. Periodic monitoring of liver function is recommended. It may also interact with other medications, so regular review by a healthcare professional is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For localized fungal infections, topical creams may be used instead of oral medicine.
Evidence: Well-establishedMay help prevent recurrent yeast infections by restoring natural flora.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, live vaccines should be avoided in immunocompromised patients. Consult your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: For vaginal yeast infections, relief may begin within 24 hours, but full effect may take a few days. For other infections, it may take longer.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.
A: It should only be used during pregnancy if clearly needed and under medical supervision. Consult your doctor.
A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for nuforce 50mg tablet
View AllAlternative brands with exact same active ingredient:
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Fuxo 50mg TabletTested & Trusted Pharma Pvt Ltd ₹5.53 73.2% CHEAPER
-
Flucade 50 DT TabletCascade India Pharmaceuticals ₹7.50 63.7% CHEAPER
-
canex 50mg tablet dtVance Health Pharmaceuticals Ltd ₹8.00 61.2% CHEAPER
-
zomav 50mg tabletMaxamus Pharma Pvt Ltd ₹8.20 60.3% CHEAPER
-
megmazole 50mg tabletRidhima Biocare ₹8.44 59.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of infections.
Fact: This medicine is only effective against fungal infections, not bacterial or viral infections. - Myth: You can stop taking it once symptoms improve.
Fact: You must complete the full course as prescribed to prevent recurrence and resistance. - Myth: It is safe to take during pregnancy without consulting a doctor.
Fact: It should only be used during pregnancy if clearly needed and under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Fluconazole 50 mg dispersible tablet
Brand Alternatives
- Zocon 50 DT Tablet