GTN Sorbitrate CR 6.4 Tablet: Complete Guide to Uses, Dosage, and Safety
When to Call Your Doctor IMMEDIATELY
- Severe chest pain that does not go away with rest or fast-acting nitrates
- Fainting or severe dizziness
- Bluish discoloration of lips, skin, or nails
- Shortness of breath or difficulty breathing
- Severe headache that does not improve
- Rapid or irregular heartbeat
- Swelling of face, lips, or throat
- Sudden weakness or numbness on one side of the body
If experiencing severe symptoms, call emergency services immediately.
What is nitrolong 6.4 tablet cr used for?
This medicine is a controlled-release oral tablet containing nitroglycerin 6.4 mg. It is used to prevent angina (chest pain) in people with coronary artery disease. It works by relaxing blood vessels to improve blood flow to the heart. It is not for immediate relief of an acute angina attack.
- Generic Name: Nitroglycerin (6.4mg)
- Manufacturer: Mankind Pharma Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nitrolong 6.4 tablet cr के बारे में (Hindi Summary)
उपयोग: यह दवा नाइट्रोग्लिसरीन 6.4 मिलीग्राम का नियंत्रित-रिलीज़ टैबलेट है, जिसका उपयोग एनजाइना (सीने में दर्द) को रोकने के लिए किया जाता है। यह रक्त वाहिकाओं को फैलाकर हृदय तक रक्त के प्रवाह को बेहतर बनाती है और हृदय पर दबाव कम करती है। यह दवा तीव्र दौरे के तत्काल उपचार के लिए नहीं है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर गर्मी लगना, और धड़कन तेज होना शामिल हैं। सिरदर्द अक्सर शुरुआत में होता है और धीरे-धीरे कम हो जाता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अत्यधिक निम्न रक्तचाप, बेहोशी, या मेथेमोग्लोबिनेमिया हो सकते हैं। यदि कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। टैबलेट को चबाएं या तोड़ें नहीं, पूरा निगल लें। शराब का सेवन न करें क्योंकि इससे चक्कर और रक्तचाप कम हो सकता है। इरेक्टाइल डिसफंक्शन की दवाएं जैसे सिल्डेनाफिल, टैडालाफिल इस दवा के साथ बिल्कुल न लें। अचानक उठने से बचें, धीरे-धीरे उठें। किसी भी सर्जरी या दंत उपचार से पहले अपने डॉक्टर को इस दवा के बारे में बताएं।
💊 nitrolong 6.4 tablet cr Uses & Benefits
- [{"condition":"Chronic stable angina prophylaxis","description":"This medicine is used to reduce the frequency of angina attacks in patients with coronary artery disease.
- It provides long-acting nitrate effects to prevent chest pain episodes.","evidence":"Well-established"},{"condition":"Vasospastic angina (Prinzmetal's angina)","description":"It helps prevent coronary artery spasms that cause chest pain at rest.
- The controlled-release formulation offers sustained protection.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Heart failure with reduced ejection fraction","description":"Sometimes used in combination with hydralazine to improve symptoms and survival, particularly in patients who cannot tolerate standard therapies.","evidence":"Moderate"},{"condition":"Anal fissure","description":"Topical nitroglycerin is used off-label to relax the anal sphincter and promote healing, but this oral form is not typically used for this purpose.","evidence":"Limited"}]
Primary treatment for: Angina pectoris
Also treats: Coronary artery disease, Vasospastic angina
📋 Drug Information
| Generic Name(s) | Nitroglycerin (6.4mg) |
| Brand Name | nitrolong 6.4 tablet cr |
| Manufacturer | Mankind Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | NO Donors |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in the original container, tightly closed, away from moisture and heat. Do not refrigerate. |
| Shelf Life | Typically 24 months from the date of manufacture. Check the expiry date on the package. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Nitroglycerin is converted in the body to nitric oxide, which activates guanylate cyclase. This leads to increased cyclic guanosine monophosphate (cGMP), causing relaxation of vascular smooth muscle. The result is dilation of veins and arteries, which reduces preload and afterload on the heart, lowering myocardial oxygen demand. It also dilates coronary arteries, improving blood flow to ischemic areas of the heart.
Mechanism Steps
💡 How to Take nitrolong 6.4 tablet cr
Strength: Controlled-release tablet, 6.4 mg
Dosage Information
| Adult Dosage | The usual adult dose of this controlled-release tablet is 2.6 mg to 6.4 mg taken once or twice daily, depending on the severity of angina and patient response. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not crush, chew, or break the tablet; swallow it whole. A nitrate-free interval of 10 to 12 hours is often recommended to prevent tolerance. Follow your doctor's instructions exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is typically required for renal impairment, but caution is advised. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with severe hepatic impairment. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 6.4 mg twice daily, but this may vary based on clinical judgment. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nitrolong 6.4 tablet cr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Sildenafil | Major | |
| Tadalafil | Major | |
| Riociguat | Major | |
| Alcohol | Moderate | |
| Beta-blockers | Moderate | |
| Calcium channel blockers | Moderate | |
| Heparin | Moderate | |
| Aspirin | Minor | |
| Ergot alkaloids | Minor | |
| Diuretics | Moderate |
🚨 Major Interactions
- Phosphodiesterase-5 inhibitors (sildenafil, tadalafil, vardenafil)
- Riociguat
⚡ Moderate Interactions
- Alcohol
- Antihypertensives (beta-blockers, calcium channel blockers, ACE inhibitors)
- Heparin
🍷 Alcohol Interaction
Alcohol can intensify the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, and increased risk of falls. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to nitroglycerin or other nitrates","Concurrent use of phosphodiesterase-5 inhibitors (sildenafil, tadalafil, vardenafil)","Concurrent use of riociguat","Severe hypotension (systolic blood pressure
⚠️ Warnings & Precautions
["This medicine may cause severe hypotension, especially when standing up. Rise slowly.","Tolerance to nitrates can develop with continuous use. A nitrate-free interval of 10-12 hours is often recommended.","Avoid alcohol while taking this medicine.","Do not use erectile dysfunction medicines while on this therapy.","Use with caution in patients with glaucoma or increased intraocular pressure.","Inform your doctor if you have liver or kidney disease.","This medicine may affect your ability to drive or operate machinery. Avoid these activities if you feel dizzy."]
🤱 Lactation Safety
It is not known whether nitroglycerin is excreted in human breast milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a nursing woman. Consult your doctor.
💊 Overdose Management
Overdose can cause severe hypotension, throbbing headache, confusion, and methemoglobinemia. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and symptomatic. If methemoglobinemia is present, methylene blue may be used. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with water. Rise slowly from sitting or lying positions to avoid dizziness. Avoid alcohol while taking this medicine because it can increase the blood-lowering effect and worsen dizziness. Do not use medicines for erectile dysfunction such as sildenafil, tadalafil, or vardenafil while on this medicine, as this can cause a dangerous drop in blood pressure. Inform all your healthcare providers that you are taking this medicine, especially before any surgery or dental procedure. Store the tablets in their original container at room temperature, away from moisture and heat. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the blood pressure-lowering effects of this medicine. They may experience more dizziness and are at higher risk of falls. Start with a lower dose and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor. This medicine is Pregnancy Category C and should be used only if clearly needed. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and cause hypotension during surgery. Your doctor may advise temporary discontinuation.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dizziness or hypotension during dental procedures. Your dentist may take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid strenuous activities that trigger angina. Warm up and cool down gradually. If you experience chest pain during exercise, stop and rest. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, especially when standing up quickly. Avoid driving or operating heavy machinery if you feel dizzy. Most people can continue their normal activities with caution. Inform your employer if your job involves operating machinery.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or your condition changes, your doctor may adjust or discontinue the dose. Always seek medical advice before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance, reducing its effectiveness. To prevent this, a nitrate-free interval of 10-12 hours is often recommended. Regular monitoring of blood pressure and angina frequency is important. Long-term use does not typically cause organ damage, but regular follow-up with your doctor is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Heart-healthy diet, regular exercise, and stress management can complement medicine.
Evidence: Well-establishedBeta-blockers, calcium channel blockers, or other nitrates may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, inform your doctor about all medicines before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid extreme temperatures. Store at room temperature and protect from moisture. If crossing time zones, consult your doctor about adjusting the dosing schedule. Do not pack it in checked baggage in case of loss. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This controlled-release tablet starts working within 30 to 60 minutes, with peak effects in 1 to 2 hours. It provides prolonged protection for 8 to 12 hours.
A: No, this medicine is for prevention. For an acute attack, use a fast-acting nitrate as prescribed by your doctor.
A: Sit or lie down immediately and rise slowly. If dizziness persists or is severe, contact your doctor.
A: Do not stop without consulting your doctor. Abrupt withdrawal can worsen angina.
🤔 Common Patient Concerns
🔄 Substitutes for nitrolong 6.4 tablet cr
View AllAlternative brands with exact same active ingredient:
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leonite 6.4mg tabletSolitaire Pharmacia Pvt Ltd ₹22.45 91.7% CHEAPER
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nitrosol cr 6.4 tabletSaaol Pharma Pvt Ltd ₹30.00 88.9% CHEAPER
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Rawnitro 6.4mg TabletRawlley Healthcare Pvt Ltd ₹37.50 86.1% CHEAPER
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ngl 6.4mg tabletDR Best pharmaceuticals Pvt Ltd ₹59.50 77.9% CHEAPER
-
Nitrokind 6.4mg Tablet CRIkon Remedies Pvt Ltd ₹63.74 76.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used to treat an ongoing heart attack.
Fact: This medicine is for prevention of angina, not for immediate relief of an acute attack. A fast-acting nitrate is used for acute attacks. - Myth: You can stop taking this medicine whenever you feel better.
Fact: Do not stop this medicine abruptly without consulting your doctor, as it may worsen angina. - Myth: Taking this medicine with erectile dysfunction drugs is safe.
Fact: Combining this medicine with erectile dysfunction drugs can cause a dangerous drop in blood pressure and is contraindicated.
🔄 Alternative Options
Generic Alternatives
- Nitroglycerin controlled-release tablets
Brand Alternatives
- Nitrocontin CR
- Nitrocine
- Angised