Bactofuran 100mg Tablet (Nitrofurantoin): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing, chest pain, or persistent cough
- Yellowing of the eyes or skin, or dark urine
- Numbness, tingling, or weakness in the hands or feet
- Severe allergic reaction with swelling of the face, lips, or throat
- Unusual tiredness, pale skin, or signs of anemia
- Severe abdominal pain or blood in vomit or stool
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is nitfur 100mg tablet used for?
This medicine contains Nitrofurantoin 100mg and is an oral antibiotic used mainly to treat uncomplicated urinary tract infections such as cystitis. It works by killing susceptible bacteria in the urine. It is usually taken twice daily with food for five days. It should not be used for kidney infections, in people with significant kidney impairment, or at term in pregnancy.
- Generic Name: Nitrofurantoin (100mg)
- Manufacturer: Rhombus Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nitfur 100mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नाइट्रोफ्यूरेंटोइन 100mg युक्त एक एंटीबायोटिक है, जिसका उपयोग मुख्य रूप से मूत्र मार्ग के संक्रमण जैसे सिस्टाइटिस के इलाज के लिए किया जाता है। यह मूत्र में बैक्टीरिया को मारकर काम करती है। यह आमतौर पर खाने के साथ दिन में दो बार पांच दिन तक ली जाती है। यह गुर्दे के संक्रमण, गंभीर गुर्दा रोग, गर्भावस्था के अंतिम चरण और एक महीने से छोटे शिशुओं के लिए नहीं है। इसका उपयोग डॉक्टर की सलाह के बिना न करें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, उल्टी, भूख न लगना, दस्त, सिरदर्द और पेट में गैस शामिल हैं। ये आमतौर पर हल्के होते हैं और खाने के साथ दवा लेने पर कम हो जाते हैं। कुछ लोगों का पेशाब गहरा पीला या भूरा हो सकता है, जो हानिकारक नहीं है। दुर्लभ मामलों में सांस लेने में तकलीफ, खांसी, सीने में दर्द, पीलिया, हाथ-पैरों में झनझनाहट, या खून की कमी हो सकती है। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और अपनी मर्जी से डोज न बदलें। इसे एक गिलास पानी के साथ खाने के बाद लें, जिससे पेट की तकलीफ कम हो और दवा अच्छी तरह अवशोषित हो। पूरा कोर्स पूरा करें, भले ही कुछ दिनों में आराम महसूस होने लगे। दिन भर पर्याप्त पानी पिएं। मैग्नीशियम ट्राइसिलिकेट युक्त एंटासिड के साथ यह दवा न लें। अगर आपको गुर्दे, लिवर, खून की बीमारी, मधुमेह या जी6पीडी की कमी है तो डॉक्टर को बताएं। सांस लेने में तकलीफ, पीलिया, झनझनाहट या एलर्जी के लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
💊 nitfur 100mg tablet Uses & Benefits
[{"condition":"Uncomplicated acute cystitis","description":"This medicine is used as a first-line oral treatment for uncomplicated lower urinary tract infection in women, typically for five days.","evidence":"Well-established"},{"condition":"Urinary tract infection prophylaxis","description":"This medicine is used in low doses for prevention of recurrent urinary tract infections in selected patients, including some women with frequent recurrences.","evidence":"Well-established"},{"condition":"Catheter-associated bacteriuria","description":"This medicine may be used to treat symptomatic urinary tract infection in patients with short-term urinary catheters when the organism is susceptible.","evidence":"Moderate"},{"condition":"Cystitis in pregnancy","description":"This medicine can be used for lower urinary tract infection in pregnancy during the first and second trimesters, but it must be avoided at term because of the risk of neonatal hemolysis.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Prostate infection","description":"This medicine is not effective for bacterial prostatitis because it does not penetrate prostate tissue adequately, so it is not recommended for this purpose.","evidence":"Not recommended"},{"condition":"Systemic bacterial infections","description":"This medicine is not used for bloodstream infections, pneumonia, or other tissue infections because it does not achieve reliable blood and tissue concentrations.","evidence":"Not recommended"}]
Primary treatment for: Uncomplicated urinary tract infection
Also treats: Recurrent urinary tract infection, Catheter-associated urinary tract infection, Cystitis in pregnancy
📋 Drug Information
| Generic Name(s) | Nitrofurantoin (100mg) |
| Brand Name | nitfur 100mg tablet |
| Manufacturer | Rhombus Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | Urinary Antiseptic-Nitrofurantoin |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C in a dry place. Keep it in the original container with the lid tightly closed. Protect it from direct sunlight, moisture, and heat. Do not store it in the bathroom. Keep it out of reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture. Always check the expiry date printed on the pack before use. Do not use the medicine after the expiry date. |
| WHO Guideline | The World Health Organization includes nitrofurantoin in its essential medicines list for urinary tract infections. It is recognized as a first-line option for uncomplicated lower urinary tract infection in many international guidelines. Always follow your local guidelines and your doctor's advice. |
| ICMR Guideline | The Indian Council of Medical Research treatment guidelines for antimicrobial use list nitrofurantoin as a preferred oral option for uncomplicated cystitis in women, where local resistance patterns allow. It is not recommended for kidney or systemic infections. Always follow your doctor's advice and local resistance data. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by entering susceptible bacteria through active transport and then being reduced by bacterial enzymes into highly reactive intermediates. These reactive compounds damage bacterial DNA, RNA, proteins, and other cellular components, which stops the bacteria from growing and eventually kills them. Because this medicine concentrates in urine, its antibacterial effect is strongest in the urinary tract, which is why it is used mainly for bladder infections.
Mechanism Steps
💡 How to Take nitfur 100mg tablet
Strength: This medicine is available as an immediate-release tablet containing 100mg of Nitrofurantoin.
Dosage Information
| Adult Dosage | For uncomplicated lower urinary tract infection in adults, the usual dose of this medicine is 100mg taken by mouth twice daily for five days. For prevention of recurrent urinary tract infection, a lower dose such as 50mg to 100mg once daily at bedtime may be used, depending on the doctor's assessment. The exact dose and duration depend on the type and severity of the infection, kidney function, and other medical conditions. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is contraindicated in infants younger than one month of age because of the risk of hemolytic anemia. |
| Elderly Dosage | Older adults may need a lower dose or shorter duration of treatment because kidney function often declines with age. Kidney function should be checked before starting this medicine. Long-term use should be avoided in older adults whenever possible because the risk of lung, nerve, liver, and blood side effects is higher. Dose must be individualized by a qualified clinician based on kidney function and overall health. |
| Renal Impairment | This medicine should not be used in people with significantly reduced kidney function, especially when creatinine clearance is below 30 mL per minute, because it may not work and side effects may increase. In mild to moderate kidney impairment, the dose may need to be reduced or the medicine avoided, depending on the doctor's assessment. Kidney function should be checked before and during treatment. |
| Hepatic Impairment | No specific dose adjustment is established for people with liver disease. This medicine should be used with caution in people with liver problems because it can rarely cause liver injury. Liver function should be monitored during treatment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine for adults with normal kidney function is 400mg per day, but the usual prescribed dose is much lower. The exact maximum dose depends on the indication, kidney function, and the doctor's judgment. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nitfur 100mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Magnesium trisilicate antacids | Major | |
| Fluoroquinolone antibiotics | Major | |
| Live typhoid vaccine | Major | |
| Warfarin | Moderate | |
| Sulfinpyrazone | Moderate | |
| Probenecid | Moderate | |
| Atropine | Minor | |
| Metoclopramide | Minor |
🚨 Major Interactions
- Magnesium trisilicate antacids
- Fluoroquinolone antibiotics such as norfloxacin
- Live typhoid vaccine
⚡ Moderate Interactions
- Warfarin
- Sulfinpyrazone
- Probenecid
🍷 Alcohol Interaction
Alcohol may worsen nausea, dizziness, and stomach upset while taking this medicine. It is best to avoid alcohol during the course of treatment, especially if you have a urinary tract infection, because alcohol can also irritate the bladder and worsen symptoms.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to nitrofurantoin or any ingredient in this medicine","Significant kidney impairment with reduced urine output","Pregnancy at term, from about 38 weeks, and during labor","Infants younger than one month of age","Glucose-6-phosphate dehydrogenase deficiency","Use for infections outside the urinary tract, such as kidney or bloodstream infections"]
⚠️ Warnings & Precautions
["This medicine should not be used for kidney infections or bloodstream infections because it does not reach adequate levels in blood and tissues.","Long-term use can cause lung reactions, nerve damage, liver injury, and blood disorders. Regular monitoring is needed.","Stop the medicine and seek medical help immediately if you develop difficulty breathing, chest pain, or a persistent cough.","Tell your doctor if you have kidney disease, liver disease, anemia, diabetes, or glucose-6-phosphate dehydrogenase deficiency.","Avoid taking antacids that contain magnesium trisilicate with this medicine.","Complete the full course as prescribed, even if symptoms improve early.","Do not use this medicine to treat viral infections such as the common cold or flu.","Older adults are more likely to experience side effects, especially with long-term use."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally considered compatible with breastfeeding when used for short courses in mothers with normal kidney function and in infants who are not glucose-6-phosphate dehydrogenase deficient. Avoid using this medicine while breastfeeding an infant younger than one month or an infant with glucose-6-phosphate dehydrogenase deficiency. Consult your doctor before use during breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause nausea, vomiting, and diarrhea. In severe cases, it may lead to liver injury, nerve damage, or blood disorders. There is no specific antidote. Treatment is supportive and includes stopping the medicine, giving fluids, and managing symptoms. If you suspect an overdose, contact your doctor or a poison control center immediately and go to the nearest emergency department. Take the medicine strip or bottle with you so the medical team knows exactly what was taken.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided there is enough time before your next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you miss several doses, contact your doctor for advice.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor and do not change the dose on your own. Swallow the tablet whole with a full glass of water and take it with food to reduce stomach upset and improve absorption. Complete the full course even if you start feeling better after a few days, because stopping early can allow the infection to return. Drink plenty of water throughout the day to help flush the urinary tract. Avoid taking this medicine with antacids that contain magnesium trisilicate, as they can reduce its absorption. Tell your doctor if you have kidney problems, liver problems, anemia, diabetes, or a condition called glucose-6-phosphate dehydrogenase deficiency. Do not use this medicine for more than the recommended duration without medical review, because long-term use increases the risk of lung and nerve side effects. Contact your doctor right away if you notice shortness of breath, chest pain, yellowing of the skin or eyes, numbness or tingling in the hands or feet, or signs of an allergic reaction. Keep all follow-up appointments so your doctor can monitor your response and check for complications.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to have reduced kidney function, which can increase the risk of side effects from this medicine. Kidney function should be checked before starting treatment. Long-term use should be avoided whenever possible because the risk of lung, nerve, liver, and blood side effects is higher. The dose may need to be reduced or the medicine avoided in older adults with kidney impairment.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, inform your doctor before starting this medicine. It is generally considered acceptable in the first and second trimesters when clearly needed, but it should be avoided at term and during labor. If you become pregnant while taking this medicine, contact your doctor immediately for advice.
🏥 Post-Surgery Considerations
If you have recently had surgery, especially urinary tract surgery or catheter placement, inform your surgeon and doctor before taking this medicine. This medicine is not suitable for preventing or treating surgical site infections outside the urinary tract. Follow your surgeon's instructions regarding antibiotics and wound care.
🦷 Dental Procedures
This medicine is not used for dental infections. If you are scheduled for a dental procedure, inform your dentist about all medicines you are taking, including this one. Do not stop this medicine without consulting your doctor. Dental procedures do not usually require changes to your urinary tract infection treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or headache in some people. Avoid strenuous exercise if you feel unwell. Light activity such as walking is usually fine. If you experience numbness or tingling in the hands or feet, stop strenuous exercise and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, headache, or stomach upset in some people. Avoid driving or operating heavy machinery if you feel unwell. Most people can continue their normal daily activities while taking this medicine. If your work involves heavy machinery or driving, inform your doctor so they can advise you appropriately.
🛑 When to Stop This Medicine
Stop this medicine and seek immediate medical help if you develop difficulty breathing, chest pain, persistent cough, yellowing of the eyes or skin, numbness or tingling in the hands or feet, or signs of a severe allergic reaction. Do not stop the medicine on your own before completing the prescribed course unless your doctor advises you to do so. If you experience bothersome side effects, contact your doctor for guidance.
📅 Long-Term Use Effects
Long-term use of this medicine can rarely cause lung reactions such as acute pneumonitis and pulmonary fibrosis, nerve damage with numbness or tingling, liver injury, and blood disorders such as anemia. The risk increases with the duration of use and in older adults. Regular monitoring of kidney function, liver function, blood counts, and lung symptoms is recommended during long-term use. The need for continued treatment should be reviewed regularly by the doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Drinking plenty of water helps flush bacteria from the urinary tract and can complement antibiotic treatment.
Evidence: SupportiveSome studies suggest cranberry products may help prevent recurrent urinary tract infections, but evidence is mixed.
Evidence: LimitedProbiotics may help restore gut flora if you develop diarrhea during antibiotic treatment.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Do not take the live typhoid vaccine while on this medicine because it may reduce the vaccine's effectiveness. Wait until the course is finished before receiving live vaccines. Inactivated vaccines are generally safe to receive during treatment. Inform your doctor about all vaccines you have recently received or plan to receive.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container with the lid tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children and pets
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it at room temperature and protect it from heat and moisture during travel. If you are crossing time zones, continue taking the medicine at evenly spaced intervals as advised by your doctor. Declare it at customs if required. Do not pack it in checked luggage; keep it in your hand baggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few hours, but noticeable relief of urinary symptoms usually takes one to two days of regular dosing. Complete the full course as prescribed.
A: Yes, taking this medicine with food improves absorption and reduces stomach upset. Take it with a meal and a full glass of water.
A: If you remember within half the dosing interval, take the missed dose. If it is almost time for the next dose, skip it and continue your regular schedule. Do not double dose.
A: It may be used in the first and second trimesters if prescribed by a doctor, but it should be avoided at term and during labor. Always consult your doctor.
A: It is best to avoid alcohol during treatment because it can worsen nausea, dizziness, and bladder irritation.
A: Store it at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and out of reach of children.
🤔 Common Patient Concerns
🔄 Substitutes for nitfur 100mg tablet
View AllAlternative brands with exact same active ingredient:
-
furadantin 100mg tabletGlaxo SmithKline Pharmaceuticals Ltd ₹9.38 74.3% CHEAPER
-
davaindia nitrofurantoin 100mg tabletDavaindia Generic Pharmacy ₹25.00 31.5% CHEAPER
-
stayhappi nitrofurantoin 100mg tabletSarvagunaushdhi Pvt Ltd ₹30.94 15.2% CHEAPER
-
Tenofur 100mg Tablet SRTNT Lifesciences ₹35.00 4.1% CHEAPER
-
urinif 100mg tabletOverseas Healthcare Pvt Ltd ₹45.26 24% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of infection.
Fact: This medicine only works for susceptible urinary tract infections. It does not treat colds, flu, or infections outside the urinary tract. - Myth: You can stop this medicine as soon as you feel better.
Fact: You must complete the full course prescribed by your doctor to prevent the infection from returning and to reduce the risk of resistance. - Myth: This medicine is safe for everyone with a urine infection.
Fact: This medicine is not safe for people with significant kidney impairment, at term in pregnancy, or for infants under one month of age. - Myth: This medicine can be taken long-term without any risk.
Fact: Long-term use can cause lung, nerve, liver, and blood side effects. It should only be used long-term under close medical supervision.
🔄 Alternative Options
Generic Alternatives
- Nitrofurantoin 100mg tablet
Brand Alternatives
- Bactofuran 100mg tablet